Results 121 to 130 of about 298,923 (289)
Angiogenin mRNA Expression Levels in Prostate Cancer Tissue [PDF]
, 2020 Introduction: Prostate cancer is the most commonly diagnosed cancer in men and second leading cause of cancer deaths. Studies have shown that tRNA fragments are upregulated in prostate cancers and play important roles in carcinogenesis.
Kirino, PhD, Yohei +4 more
core +1 more source
Activation of Caged Functional RNAs by An Oxidative Transformation
ChemBioChem, EarlyView.RNAs containing 2‐thiouridine (2sUrd) in place of uridine (Urd) can exhibit loss of function. Treatment with hydrogen peroxide can convert 2sUrd to Urd. We show that a 2sUrd‐containing aptamer and ribozyme can exhibit recovery of function upon treatment with hydrogen peroxide, allowing for redox‐switched functional behavior.
Joseph M. Heili +2 more
wiley +1 more source
Neuropsychiatric Disease and TreatmentPan Jing,1,2 Haihang Yu,1,2 Wenxi Sun,3,4 Ming Liang,5 Tingting Xia,5 Haidong Yang,6 Peng Chen,3,4 Jin Li,3,4 Xiaobin Zhang3,4 1Department of Psychiatry, Affiliated Kangning Hospital of Ningbo University, Ningbo, People’s Republic of China; 2Department ...
Jing P +8 more
doaj
Purification and some Properties of Leucyl‐tRNA Synthetase from Bacillus stearothermophilus [PDF]
, 1969 J Vanhumbeeck, Paul F. Lurquin
openalex +1 more source
Designing Enzymatic Reactivity with an Expanded Palette
ChemBioChem, EarlyView.Innovation in biocatalysis is rapidly increasingly the diversity of catalytic reactivity that can be mediated by enzymes, addressing a key bottleneck for their widespread adoption in industrial chemical synthesis. A key approach to this is building enzymes with unnatural catalytic components that provide an expanded palette with new possibilities for ...
Reuben B. Leveson‐Gower
wiley +1 more source
ChemBioChem, EarlyView.An affitin derived from the Sac7d scaffold enables the light‐controlled affinity purification of antibodies under physiological conditions, thus overcoming limitations of protein A chromatography. X‐ray crystallographic analysis and affinity measurements reveal complex formation with Fc at the CH2/CH3 junction, similar to protein A/G and FnRn. Combined
Felix Veitl +7 more
wiley +1 more source
The Binding of Peptidyl‐tRNA and Acylaminoacyl‐tRNA to E. coli Ribosomes [PDF]
, 1969 Natalia Sánchez de Groot +2 more
openalex +1 more source
ChemBioChem, EarlyView.FtsZ is the only target protein that has been biochemically confirmed to be hydrolyzed both in vitro and in bacterial cells. Coupled with activity‐based protein profiling of nonribosomal peptide synthetases, the ClpP‐ADEP1 proteolytic complex that degrades the surfactin synthetases SrfAA and SrfAB in cell lysates and bacterial cells is demonstrated ...
Fumihiro Ishikawa +4 more
wiley +1 more source
Precision Medical Sciences, Volume 11, Issue 4, Page 195-208, December 2022., 2022 Three m7G‐related lncRNAs (LINC00412, REPIN1‐AS1, and RPH3AL‐AS1) are associated with the prognosis of gastric cancer patients and may be novel biomarkers. These lncRNAs may also have an influence on the immune status of gastric cancer patients. Abstract Long noncoding RNA (lncRNA) may act as a biomarker to predict the overall survival (OS) of cancer ...
Peisen Guo +6 more
wiley +1 more source