Noncanonical Nucleotides in the Genome Around the Maternal‐Zygotic Transition
In this paper, Kazzazi et al. provide a comprehensive review of the dynamics of nonconventional nucleotides in the genome during early developmental stages, hypothesizing a potential role for these nucleotides in the activation of the zygotic genome. ABSTRACT From the very moment of fertilization and throughout development, the cells of animal embryos ...
Latifa Kazzazy +7 more
wiley +1 more source
Transfer RNA Modifications in the Immune System Participate in Disease Pathogenesis. [PDF]
Ma X +8 more
europepmc +1 more source
Mechanistic insights into tRNA translocation on the ribosome
The ribosome is a highly conserved cellular complex and constitutes the center of protein biosynthesis. As the ribosome consists to about 2/3 of ribosomal RNA (rRNA), the rRNA is involved in most steps of translation.
Koch, Miriam
core
Abstract We report a case of a premature, growth‐restricted female infant with feeding intolerance and coagulopathy, treated initially for sepsis, who progressed to neonatal acute liver failure and end‐stage hepatic encephalopathy after a prolonged hospitalization with extensive diagnostic evaluation, and was found by autopsy to have histopathologic ...
Adrienne Bruder +3 more
wiley +1 more source
Insights Into the Structural Features, Codon Usage Patterns, and Phylogenetic Analysis in <i>Neoniphon argenteus</i> (Teleostei: Holocentriformes) Based on Complete Mitochondrial Genome. [PDF]
Xie L +7 more
europepmc +1 more source
The Regulatory Role and Mechanism of Myoferlin in Mitophagy During Papillary Thyroid Carcinogenesis
ABSTRACT Papillary thyroid carcinoma (PTC) is the most prevalent subtype of thyroid cancer; however, the regulatory mechanisms by which mitophagy influences its progression remain inadequately elucidated. This study sought to examine the role of myoferlin (MYOF) in mitophagy and its molecular basis during PTC development. Utilizing three paired PTC and
Wen‐Chao Lyu +6 more
wiley +1 more source
Ovarian hormone loss modifies the nucleic acid cargo of circulating extracellular vesicles and skeletal muscle metabolism after acute exercise in rats. [PDF]
Puumalainen V +7 more
europepmc +1 more source
ABSTRACT Aspartyl‐tRNA synthetase 2 (DARS2), the mitochondrial enzyme responsible for aminoacylation of aspartyl‐tRNA, is traditionally known for its effect on protein synthesis. Recently, DARS2 is reported to be implicated in tumorigenesis. However, its specific effect on breast cancer (BC) is poorly understood.
Na Wang, Ming Huang
wiley +1 more source
The complete mitochondrial genome of <i>Acanthaspis geniculata</i> (Hsiao, 1976) (Hemiptera: Reduviidae) and its phylogenetic analyses. [PDF]
Liu W, Chen J, Lin J, Wang P, Cheng X.
europepmc +1 more source

