Results 171 to 180 of about 234,592 (250)

Enterovirus infections in children

open access: yesPediatric Investigation, EarlyView.
Enteroviruses (EVs) are major pathogens causing a wide spectrum of diseases in children worldwide. This review summarizes the epidemiology, virology, viral replication, and virus‐host interactions of EVs. It also highlights current advances in clinical diagnosis, antiviral therapies, and vaccine development, providing insights into future strategies ...
Xiangpeng Chen   +11 more
wiley   +1 more source

Biosurfactant production by Pseudomonas aeruginosa isolated from mining waste: From genomic analysis to development of a polymeric composite for removal of hexavalent chromium

open access: yesPolymer International, EarlyView.
Biosurfactant was produced by Pseudomonas aeruginosa using andiroba waste from Amazonia. A biosurfactant–alginate composite (Alg/BioS) was successfully synthesized via ionotropic gelation, and achieved up to 70% Cr6+ removal from water. Abstract Environmental contamination by heavy metals represents a significant challenge due to their persistence in ...
Paulo Diniz Austriaco   +11 more
wiley   +1 more source

Aspartic Protease Inhibition Induces Proteomic Remodeling in Paracoccidioides brasiliensis

open access: yesPROTEOMICS, EarlyView.
ABSTRACT Paracoccidioidomycosis (PCM) is a major systemic mycosis in Latin America caused by Paracoccidioides brasiliensis, yet the contribution of aspartic proteases to fungal physiology and pathogenicity remains poorly understood. Here, we employed data‐independent acquisition (DIA)‐based quantitative proteomics to investigate the impact of pepstatin
Sarah Fernandes Lima   +6 more
wiley   +1 more source

An (αβ)2 Architecture of the Arabidopsis thaliana tRNA Splicing Endonuclease Complex: Structural Modeling and Evolutionary Analyses

open access: yesProteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT The tRNA splicing endonuclease (TSEN) removes introns from precursor tRNAs (pre‐tRNAs) in eukaryotes and archaea, but the architecture and subunit organization of plant TSEN remain poorly defined. Here, we integrated in planta bimolecular fluorescence complementation (BiFC) assays with AlphaFold3 (AF3)‐based structural modeling, molecular ...
Mohammad Moniruzzaman   +2 more
wiley   +1 more source

Ginsenoside Rh1 Attenuates Alzheimer's Disease‐Like Deficits by Modulating Oxidative Stress and Mitochondrial Dysfunction via SIRT1‐Related Signaling

open access: yesPhytotherapy Research, EarlyView.
Rh1 attenuates oxidative stress and mitochondrial dysfunction through SIRT1‐related signaling. ABSTRACT Alzheimer's disease (AD) remains a progressive neurodegenerative disorder with limited therapeutic options. Ginsenoside Rh1 has been reported to possess neuroprotective properties, yet its specific role and underlying mechanisms in AD are not fully ...
Shi‐Lu Li   +10 more
wiley   +1 more source

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