Results 181 to 190 of about 404,299 (351)

Internal Ubiquitin Electrophiles for Covalent Trapping and Inhibition of Deubiquitinases

open access: yesChemBioChem, EarlyView.
GA: Genetically encoded internal electrophiles in ubiquitin (Ub) enable the profiling of multivalent interaction interfaces, addressing a key limitation of current Ub‐based activity‐based probes. In this study, these probes capture a Ub–deubiquitinase interaction with minimal structural perturbation and serve as selective diUb probes that covalently ...
Nipuni M. Pannala   +7 more
wiley   +1 more source

Das Regensburger Symposium : ein Bericht

open access: yesBrünner Beiträge zur Germanistik und Nordistik, 2017
Jan Trna
doaj   +1 more source

Rapid discovery and evolution of orthogonal aminoacyl-tRNA synthetase–tRNA pairs

open access: yesNature Biotechnology, 2020
Daniele Cervettini   +6 more
semanticscholar   +1 more source

ThiF‐Like Enzyme Chemistry in Primary and Secondary Metabolism

open access: yesChemBioChem, EarlyView.
ThiF‐like enzymes are a widespread protein family found in disparate biosynthetic pathways. They are unified by their use of an NTP to modify a carboxylate, generating an activated species prone to nucleophilic addition. This common intermediate is then targeted by diverse nucleophiles, including persulfide or amino acid side chains, to yield a variety
Keelie S. Butler   +2 more
wiley   +1 more source

In Sloterdijks Weltinnenraum : ein Konferenzbericht

open access: yesBrünner Beiträge zur Germanistik und Nordistik, 2017
Jan Trna
doaj   +1 more source

Koordinace vzdělávacích cílů v Občanské a Základní škole

open access: yesPedagogická Orientace, 2018
N ...
Josef Trna, Eva Trnová
doaj  

Enhancing Antigen Recognition of Living Cells by Site‐Specific VHH Antibody Conjugation

open access: yesChemBioChem, EarlyView.
Site‐specific incorporation of azido‐phenylalanine (AzF) into antibodies enables precise conjugation, allowing anti‐mCherry variable domains of heavy‐chain‐only antibodies (VHHs) to be aligned and immobilized on dibenzylcyclooctyne (DBCO)‐coated glass via click chemistry.
Chengyuan Zhu   +3 more
wiley   +1 more source

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