Results 21 to 30 of about 241,053 (344)
On the mechanism of tRNA methylase-tRNA recognition [PDF]
Nucleic Acids Research, 1976 In order to further elucidate the mechanism of tRNA methylase-tRNA intreaction the methylation of some individual tRNAs separately and by pairs was performed. In conditions of tRNA excess the methylation rates of positionally analogous nucleotides in tRNA molecules are not summed up when two substrates are simultaneously present in the reaction mixture.
A S, Gambaryan +2 more
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Direct Nanopore Sequencing of Individual Full Length tRNA Strands
bioRxiv, 2021 We describe a method for direct tRNA sequencing using the Oxford Nanopore MinION. The principal technical advance is custom adapters that facilitate end-to-end sequencing of individual tRNA molecules.
Niki Thomas +5 more
semanticscholar +1 more source
tRNA Recognition by Glutamyl-tRNA Reductase [PDF]
Journal of Biological Chemistry, 2004 During the first step of porphyrin biosynthesis in Archaea, most bacteria, and in chloroplasts glutamyl-tRNA reductase (GluTR) catalyzes the NADPH-dependent reduction of glutamyl-tRNA to glutamate-1-semialdehyde. Elements in tRNA(Glu) important for utilization by Escherichia coli GluTR were determined by kinetic analysis of 51 variant transcripts of E.
Lennart, Randau +8 more
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RNA: A publication of the RNA Society, 2020 The aminoacyl-tRNA synthetases are an essential and universally distributed family of enzymes that plays a critical role in protein synthesis, pairing tRNAs with their cognate amino acids for decoding mRNAs according to the genetic code. Synthetases help
Miguel Angel Rubio Gomez, M. Ibba
semanticscholar +1 more source
Molecular Cell, 2005 Two recently published papers (Takano et al., 2005 and Shaheen and Hopper, 2005) demonstrate that in S. cerevisiae, cytoplasmic tRNAs can be transported into the nucleus. This retrograde movement may expose mature tRNAs to nuclear proofreading or it may regulate tRNA availability in response to amino acid availability.
Dahlberg, James, Lund, Elsebet
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Quantitative tRNA-sequencing uncovers metazoan tissue-specific tRNA regulation
Nature Communications, 2020 Transfer RNAs (tRNA) are quintessential in deciphering the genetic code; disseminating nucleic acid triplets into correct amino acid identity. While this decoding function is clear, an emerging theme is that tRNA abundance and functionality can ...
Otis Pinkard +3 more
semanticscholar +1 more source
Molecular Basis and Consequences of the Cytochrome c-tRNA Interaction. [PDF]
, 2016 The intrinsic apoptosis pathway occurs through the release of mitochondrial cytochrome c to the cytosol, where it promotes activation of the caspase family of proteases.
Christian, Thomas +6 more
core +2 more sources
Emerging Aspects of Jumbo Bacteriophages
Infection and Drug Resistance, 2021 Amina Nazir,1,2 Azam Ali,3 Hong Qing,1 Yigang Tong2 1Key Laboratory of Molecular Medicine and Biotherapy in the Ministry of Industry and Information Technology, Department of Biology, School of Life Sciences, Beijing Institute of Technology, Beijing ...
Nazir A, Ali A, Qing H, Tong Y
doaj
Phenylalanyl‐tRNA, Lysyl‐tRNA, Isoleucyl‐tRNA and Arginyl‐tRNA Synthetases [PDF]
European Journal of Biochemistry, 1980 Ten analogs of ATP have been tested in the ATP/PPi exchange reaction of Phenylalanyl‐tRNA, lysyl‐tRNA, isoleucyl‐tRNA and arginyl‐tRNA synthetases from baker's yeast. Three compounds are substrates for Phenylalanyl‐tRNA, seven for lysyl‐tRNA, two for isoleucyl‐tRNA and five for arginyl‐tRNA synthetase. Their Km and V values have been determined.
W, Freist, F, Cramer
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DEREGULATED EXPRESSIONS OF MYC ALTER THE EXPRESSIONS OF tRNAS IN BREAST CANCER CELLS
Sabiad, 2023 Objective: The protein synthesis process is started with DNA being transcribed into mRNA in the nucleus, then mRNA is transported to the cytoplasm and attaches to a ribosome in order to be translated into a protein.
Pervin Elvan Tokgün, Onur Tokgün
doaj +1 more source