Results 21 to 30 of about 298,923 (289)
Principles of Palliative and Supportive Care in Pancreatic Cancer: A Review
Biomedicines, 2023 Pancreatic adenocarcinoma (PDAC) is well known for its poor survival time. Clinical symptoms are painless jaundice or abdominal or back pain. Less specific symptoms often appear that make diagnosis difficult, e.g., weight loss, loss of appetite, nausea ...
Robert Mazur, Jan Trna
doaj +1 more source
The biogenesis pathway of tRNA-derived piRNAs in Bombyx germ cells. [PDF]
, 2017 Transfer RNAs (tRNAs) function in translational machinery and further serves as a source of short non-coding RNAs (ncRNAs). tRNA-derived ncRNAs show differential expression profiles and play roles in many biological processes beyond translation ...
Honda, Shozo +5 more
core +2 more sources
ChemBioChem, Volume 23, Issue 23, December 5, 2022., 2022 Housing sulfur: Certain fungi produce diketopiperazine compounds with a transannular sulfur bridge. These so‐called epipolythiodioxopiperzines are toxic by non‐specifically interacting with intracellular proteins and contribute to fungal pathogenicity. Producer strains serve as bio‐pesticides but also question safety of food fermentation.
Eva M. Huber
wiley +1 more source
Chemical Proteomics Reveals Protein Tyrosination Extends Beyond the Alpha‐Tubulins in Human Cells**
ChemBioChem, Volume 23, Issue 23, December 5, 2022., 2022 Protein post‐translational modifications allow cells to swiftly adjust activity and localization of proteins. Here, we developed a chemical proteomic approach to determine a protein tyrosination status using an O‐propargyl tyrosine probe. We show that tyrosination modifies previously described alpha‐tubulins with ‐EEY C‐terminal sequence together with ...
Dmytro Makarov, Pavel Kielkowski
wiley +1 more source
Sri Lankan Journal of Infectious Diseases, 2014 Introduction: The complete mitochondrial (mt) genomes of nematodes sequenced thus far are circular and small in length, containing 37 genes, including 12–13 protein-coding genes: namely, cytochrome oxidase subunits 1–3 (cox1–3), nicotinamide adenine ...
S Wickramasinghe, L Yatawara, T Agatsuma
doaj +1 more source
Analysis of the complete mitochondrial genome sequence of Palinura homarus
Mitochondrial DNA. Part B. Resources, 2017 The complete mitochondrial genome sequence of Palinura homarus was obtained using PCR amplification and walking sequencing (GenBank accession no. JN_542716). The complete mitochondrial genome of P.
Bao-hua Xiao +4 more
doaj +1 more source
Biallelic mutations in valyl-tRNA synthetase gene VARS are associated with a progressive neurodevelopmental epileptic encephalopathy. [PDF]
, 2019 Aminoacyl-tRNA synthetases (ARSs) function to transfer amino acids to cognate tRNA molecules, which are required for protein translation. To date, biallelic mutations in 31 ARS genes are known to cause recessive, early-onset severe multi-organ diseases ...
Accogli, Andrea +28 more
core +2 more sources
Einige Bemerkungen zu Übersetzungen ausgewählter Romane von Thomas Bernhard aus den 80er Jahren
Brünner Beiträge zur Germanistik und Nordistik, 2018 The aim of this paper is to analyze Bernhard's specific features which distinguish his literary language and which also represent problematic translation issues.
Jan Trna
doaj +1 more source
YAMAT-seq: an efficient method for high-throughput sequencing of mature transfer RNAs. [PDF]
, 2017 Besides translation, transfer RNAs (tRNAs) play many non-canonical roles in various biological pathways and exhibit highly variable expression profiles.
Honda, Shozo +5 more
core +2 more sources
Allosteric collaboration between elongation factor G and the ribosomal L1 stalk directs tRNA movements during translation [PDF]
, 2009 Determining the mechanism by which transfer RNAs (tRNAs) rapidly and precisely transit through the ribosomal A, P and E sites during translation remains a major goal in the study of protein synthesis.
Chris H. Wiggins +6 more
core +4 more sources