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Non-proteinogenic (np) amino acids in the food chain present challenges for the human translation machinery. Here the authors show that, while AlaRS and ProRS activate toxic np azetidine-2-carboxylic acid (Aze) present in sugar beets and lilies, only the
Youngzee Song+10 more
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Introduction: The complete mitochondrial (mt) genomes of nematodes sequenced thus far are circular and small in length, containing 37 genes, including 12–13 protein-coding genes: namely, cytochrome oxidase subunits 1–3 (cox1–3), nicotinamide adenine ...
S Wickramasinghe, L Yatawara, T Agatsuma
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Initiator tRNA genes template the 3\u27 CCA end at high frequencies in bacteria. [PDF]
BACKGROUND: While the CCA sequence at the mature 3\u27 end of tRNAs is conserved and critical for translational function, a genetic template for this sequence is not always contained in tRNA genes.
Ardell, David H., Hou, Ya-Ming
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In the original version of this Article, extraneous text not belonging to the article was accidentally appended to end of the first paragraph of the discussion. This error has now been corrected in both the PDF and HTML versions of the Article.
Youngzee Song+10 more
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Two recently published papers (Takano et al., 2005 and Shaheen and Hopper, 2005) demonstrate that in S. cerevisiae, cytoplasmic tRNAs can be transported into the nucleus. This retrograde movement may expose mature tRNAs to nuclear proofreading or it may regulate tRNA availability in response to amino acid availability.
Dahlberg, James, Lund, Elsebet
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Molecular Basis and Consequences of the Cytochrome c-tRNA Interaction. [PDF]
The intrinsic apoptosis pathway occurs through the release of mitochondrial cytochrome c to the cytosol, where it promotes activation of the caspase family of proteases.
Christian, Thomas+6 more
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Emerging Aspects of Jumbo Bacteriophages
Amina Nazir,1,2 Azam Ali,3 Hong Qing,1 Yigang Tong2 1Key Laboratory of Molecular Medicine and Biotherapy in the Ministry of Industry and Information Technology, Department of Biology, School of Life Sciences, Beijing Institute of Technology, Beijing ...
Nazir A, Ali A, Qing H, Tong Y
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The biogenesis pathway of tRNA-derived piRNAs in Bombyx germ cells. [PDF]
Transfer RNAs (tRNAs) function in translational machinery and further serves as a source of short non-coding RNAs (ncRNAs). tRNA-derived ncRNAs show differential expression profiles and play roles in many biological processes beyond translation ...
Honda, Shozo+5 more
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This essay deals with the stage play "Alices Reise in die Schweiz" (Alice's trip to Switzerland) by Lukas Bärfuss, specifically focusing on the main character Gustav.
Jan Trna
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Complete mitochondrial genome of Saiga tatarica (Ruminantia; Pecora; Bovidae) isolate Wuwei in China
This report described the complete mitochondrial genome of the Saiga antelope, Saiga tatarica, from the Gansu Endangered Animal Research Center (GEARC) in Gansu Province, China.
Xin Ding+7 more
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