Results 41 to 50 of about 404,299 (351)

Complete mitochondrial genome of Saiga tatarica (Ruminantia; Pecora; Bovidae) isolate Wuwei in China

open access: yesMitochondrial DNA. Part B. Resources, 2017
This report described the complete mitochondrial genome of the Saiga antelope, Saiga tatarica, from the Gansu Endangered Animal Research Center (GEARC) in Gansu Province, China.
Xin Ding   +7 more
doaj   +1 more source

Biallelic mutations in valyl-tRNA synthetase gene VARS are associated with a progressive neurodevelopmental epileptic encephalopathy. [PDF]

open access: yes, 2019
Aminoacyl-tRNA synthetases (ARSs) function to transfer amino acids to cognate tRNA molecules, which are required for protein translation. To date, biallelic mutations in 31 ARS genes are known to cause recessive, early-onset severe multi-organ diseases ...
Accogli, Andrea   +28 more
core   +2 more sources

Exosomal tRNA-derived small RNA as a promising biomarker for cancer diagnosis

open access: yesMolecular Cancer, 2019
tRNA-derived small RNA (tsRNA) is a novel regulatory small non-coding RNA and participates in diverse physiological and pathological processes. However, the presence of tsRNAs in exosome and their diagnostic potential remain unclear.
Lei Zhu   +11 more
semanticscholar   +1 more source

Complete mitochondrial genome sequence of Catla catla (Hamilton, 1822) from the Halda river of Bangladesh

open access: yesMitochondrial DNA. Part B. Resources, 2020
Catla (Catla catla) is one of the fastest-growing major carp found in South Asia as well as Bangladesh. Catla catla is the second most popular indigenous carp species in the freshwater aquaculture industry of Bangladesh due to its relatively good taste ...
M. M. Kibria   +5 more
doaj   +1 more source

Principles of Palliative and Supportive Care in Pancreatic Cancer: A Review

open access: yesBiomedicines, 2023
Pancreatic adenocarcinoma (PDAC) is well known for its poor survival time. Clinical symptoms are painless jaundice or abdominal or back pain. Less specific symptoms often appear that make diagnosis difficult, e.g., weight loss, loss of appetite, nausea ...
Robert Mazur, Jan Trna
doaj   +1 more source

The structure of Rph, an exoribonuclease from Bacillus anthracis, at 1.7 angstrom resolution [PDF]

open access: yes, 2008
Maturation of tRNA precursors into functional tRNA molecules requires trimming of the primary transcript at both the 5' and 3' ends. Cleavage of nucleotides from the 3' stem of tRNA precursors, releasing nucleotide diphosphates, is accomplished in ...
Blagova, Elena V.   +5 more
core   +2 more sources

tRNA splicing [PDF]

open access: yes, 1998
Introns interrupt the continuity of many eukaryal genes, and therefore their removal by splicing is a crucial step in gene expression. Interestingly, even within Eukarya there are at least four splicing mechanisms.
Abelson, John   +2 more
core   +1 more source

tRNA fragments (tRFs) guide Ago to regulate gene expression post-transcriptionally in a Dicer-independent manner

open access: yesRNA: A publication of the RNA Society, 2018
tRNA related RNA fragments (tRFs), also known as tRNA-derived RNAs (tdRNAs), are abundant small RNAs reported to be associated with Argonaute proteins, yet their function is unclear.
Canan Kuscu   +5 more
semanticscholar   +1 more source

The stress specific impact of ALKBH1 on tRNA cleavage and tiRNA generation

open access: yesbioRxiv, 2020
tiRNAs are small non-coding RNAs produced when tRNA is cleaved under stress. tRNA methylation modifications has emerged in recent years as important regulators for tRNA structural stability and sensitivity to cleavage and tiRNA generation during stress ...
Sherif Rashad   +6 more
semanticscholar   +1 more source

tRNA-Derived Small RNA: A Novel Regulatory Small Non-Coding RNA

open access: yesGenes, 2018
Deep analysis of next-generation sequencing data unveils numerous small non-coding RNAs with distinct functions. Recently, fragments derived from tRNA, named as tRNA-derived small RNA (tsRNA), have attracted broad attention. There are mainly two types of
Siqi Li, Zhengping Xu, J. Sheng
semanticscholar   +1 more source

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