Results 181 to 190 of about 110,116 (296)

Suboptimal codon pairs trigger ribosome collisions and cellular quality control responses in tRNA modification mutants. [PDF]

Nucleic Acids Res
Wu J, Eggers C, Sin O, Koziej Ł, Mancilla H, Mollet F, Schöler HR, Drexler HCA, Ranff T, Fufezan C, Kraft C, Glatt S, Bruder JM, Leidel SA.   +13 more
europepmc   +1 more source

Phytochemical content, antioxidant and antibacterial properties of Typhonium flagelliforme cultivated via soil and hydroponic methods

JSFA reports, EarlyView.
Abstract Background Typhonium flagelliforme is a medicinal herb in the Araceae family, widely distributed in Southeast Asia. This study aimed to evaluate the effects of hydroponic and soil‐based cultivation systems on the phytochemical content and bioactivity of T. flagelliforme. Results Using liquid chromatography‐mass spectrometry (LC‐MS) analysis, 9
Yen Ning Lee, Norsharina Md Saad, Siti Rokhiyah Ahmad Usuldin, Seetha Jaganathan King, Wee Sim Choo   +4 more
wiley   +1 more source

tRNA modification profiling reveals epitranscriptome regulatory networks in Pseudomonas aeruginosa. [PDF]

Nucleic Acids Res
Sun J, Wu J, Yuan Y, Fan L, Chua WLP, Ling YHS, Balamkundu S, Dwijapriya, Chay HSS, Begley TJ, de Crécy-Lagard V, Dziergowska A, Dedon PC.   +12 more
europepmc   +1 more source

The universal Sua5/TsaC family evolved different mechanisms for the synthesis of a key tRNA modification. [PDF]

Front Microbiol, 2023
Pichard-Kostuch A, Da Cunha V, Oberto J, Sauguet L, Basta T.   +4 more
europepmc   +1 more source

Oncogenic KRAS Rewires Stress Granule Dynamics: Mechanisms and Therapeutic Opportunities

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Stress granules (SGs) are dynamic, membrane‐less structures that form in response to various cellular stresses, including metabolic, oxidative, and therapeutic challenges. They function as adaptive hubs and reorganize protein synthesis and signaling networks to help cells survive under stress. In cancer, these condensates are often hijacked to
Msimisi Ndzinisa, Birhanetensay Masresha Altaye, Yuh‐Pyng Sher   +2 more
wiley   +1 more source

METTL1-Mediated M⁷G tRNA Modification Promotes Residual Liver Regeneration After Hepatectomy via Translational Control. [PDF]

Adv Sci (Weinh)
Huang M, Lin S, Zhao Y, Chen J, Huang L, Liu Y, Huang Z, An D, Zhang Y, Song Z, Yu X, Hua Y, Wang J, Wang W, Guo Y, Kuang M, Wang F, Lin S, Shen S.   +18 more
europepmc   +1 more source

Adaptation to Overflow Metabolism by Mutations That Impair tRNA Modification in Experimentally Evolved Bacteria. [PDF]

mBio, 2023
Muraski MJ, Nilsson EM, Fritz MJ, Richardson AR, Alexander RW, Cooper VS.   +5 more
europepmc   +1 more source

Non‐Histone Lactylation: A New Frontier in Cerebral Ischemia‐Reperfusion Injury

Med Research, EarlyView.
ABSTRACT Reperfusion therapy is the mainstay of treatment for ischemic stroke (IS) but frequently exacerbates secondary injury. Following cerebral ischemia and hypoxia, lactate accumulates markedly. Traditionally regarded as a metabolic byproduct, lactate has gained new significance with the discovery of protein lactylation. In addition to experimental
Minghui Tang, Yuying Mo, Zhishan Ling, Yuting Zeng, Qi Zhang, Shuqi Zheng, Shuyang Wen, Yupeng Xiao, Siying Long, Tingting Yang, Qianru Li, Wenjie Shi, Guozhi Huang, Qing Zeng   +13 more
wiley   +1 more source

Are Bacterial Processes Dependent on Global Ribosome Pausing Affected by tRNA Modification Defects? [PDF]

J Mol Biol
de Crécy-Lagard V, Baharoglu Z, Yuan Y, Boël G, Babor J, Bacusmo JM, Dedon PC, Ho P, Hummels KR, Kearns D.   +9 more
europepmc   +1 more source

Single-read tRNA-seq analysis reveals coordination of tRNA modification and aminoacylation and fragmentation. [PDF]

Nucleic Acids Res, 2023
Hernandez-Alias X, Katanski CD, Zhang W, Assari M, Watkins CP, Schaefer MH, Serrano L, Pan T.   +7 more
europepmc   +1 more source