Overview of tRNA Modifications in Chloroplasts [PDF]
Microorganisms, 2022 The chloroplast is a promising platform for biotechnological innovation due to its compact translation machinery. Nucleotide modifications within a minimal set of tRNAs modulate codon–anticodon interactions that are crucial for translation efficiency ...
Martin Hohmann-Marriott +1 more
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tRNA modifications: greasing the wheels of translation and beyond [PDF]
RNA BiologyTransfer RNA (tRNA) is one of the most abundant RNA types in cells, acting as an adaptor to bridge the genetic information in mRNAs with the amino acid sequence in proteins.
Zhipeng Lu, Minjie Zhang
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Phytophthora capsici infection causes dynamic alterations in tRNA modifications and their associated gene candidates in black pepper [PDF]
Computational and Structural Biotechnology Journal, 2022 The efforts to signify the relevance of tRNA modifications were always within the limits of prokaryotes, humans, and some fewer model plant systems. The story of tRNA modifications in higher plants is still overlooked, especially in non-model spice crops.
Aswathi Usha +4 more
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tRNA modifications in cancer: from molecular mechanisms to clinical translation [PDF]
Biomarker ResearchtRNA modifications, the most extensively and diversely modified class of RNA across all domains of life, have garnered significant and growing attention in research over the past decade.
Cillian H. Cheng, Chi Chun Wong
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Genome-wide profiling of tRNA modifications by Induro-tRNAseq reveals coordinated changes [PDF]
Nature CommunicationsWhile all native tRNAs undergo extensive post-transcriptional modifications as a mechanism to regulate gene expression, mapping these modifications remains challenging.
Yuko Nakano +14 more
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Decoding human tRNA modifications and crosstalk by enhanced single-read analysis [PDF]
Genome BiologyBackground Transfer RNA (tRNA) modifications play important roles in regulating gene expression and protein synthesis, yet their dynamic interplay remains elusive.
Mahdi Assari +8 more
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tRNA Modifications: Impact on Structure and Thermal Adaptation
Biomolecules, 2017 Transfer RNAs (tRNAs) are central players in translation, functioning as adapter molecules between the informational level of nucleic acids and the functional level of proteins.
Mario Mörl, Mörl Mario
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tRNA Modifications and Dysregulation: Implications for Brain Diseases [PDF]
Brain SciencesTransfer RNAs (tRNAs) are well-known for their essential function in protein synthesis. Recent research has revealed a diverse range of chemical modifications that tRNAs undergo, which are crucial for various cellular processes.
Xinxin Lv +3 more
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Dynamic changes in tRNA modifications and abundance during T cell activation [PDF]
Proceedings of the National Academy of Sciences of the United States of America, 2021 Inbal Eizenberg +2 more
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A tRNA modification in Mycobacterium tuberculosis facilitates optimal intracellular growth
eLife, 2023 Diverse chemical modifications fine-tune the function and metabolism of tRNA. Although tRNA modification is universal in all kingdoms of life, profiles of modifications, their functions, and physiological roles have not been elucidated in most organisms ...
Francesca G Tomasi +3 more
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