Results 21 to 30 of about 55,926 (239)
tRNA modifications in viral replication. [PDF]
J Biol ChemPathirage C +2 more
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The host tRNA epitranscriptome: A new player in RNA virus infections
Frontiers in Virology, 2022 Viruses completely depend on the host translation machineries to express the viral proteins. Recent data reveal an unprecedented interaction of positive strand RNA ((+)RNA) viruses with the host tRNA epitranscriptome to favor viral protein expression via
Marc Talló-Parra +2 more
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A quantitative systems approach reveals dynamic control of tRNA modifications during cellular stress. [PDF]
PLoS Genetics, 2010 Decades of study have revealed more than 100 ribonucleoside structures incorporated as post-transcriptional modifications mainly in tRNA and rRNA, yet the larger functional dynamics of this conserved system are unclear. To this end, we developed a highly
Clement T Y Chan +5 more
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Neural Regeneration Research, 2020 Over the past decades, tRNA was found to be a rich hub of RNA modifications such as 1-methyladenosine and 5-methycytosine modifications and others, holding more than half of all modifications occurring in RNA molecules.
Sherif Rashad +2 more
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Modification of tRNA as a regulatory device [PDF]
Molecular Microbiology, 1993 SummaryOur knowledge of the different biological roles of tRNA modification has increased considerably in recent years. Not only have we learned about how modified nucleosides affect the performance of tRNA in translation, but also how they influence regulation of intermediary metabolism, antibiotics production, gene expression in eukaryotic viruses ...
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Prediction of uridine modifications in tRNA sequences [PDF]
BMC Bioinformatics, 2014 In past number of methods have been developed for predicting post-translational modifications in proteins. In contrast, limited attempt has been made to understand post-transcriptional modifications. Recently it has been shown that tRNA modifications play direct role in the genome structure and codon usage.
Bharat Panwar, Gajendra P. S. Raghava
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Translational regulation by oxidative desulfuration of tRNA modifications. [PDF]
Nat CommunModifications in the anticodon region of transfer RNA (tRNA) are essential for accurate and efficient protein synthesis. 5-Methyl-2-thiouridine derivatives (xm5s2U) are major modifications at the wobble position of tRNA anticodons decoding purine-ending two-codon sets.
Mo Y +12 more
europepmc +4 more sources
Life, 2022 The genetic code evolved around the reading of the tRNA anticodon on the primitive ribosome, and tRNA-34 wobble and tRNA-37 modifications coevolved with the code.
Lei Lei, Zachary Frome Burton
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Biosynthesis and Degradation of Sulfur Modifications in tRNAs [PDF]
International Journal of Molecular Sciences, 2021 Various sulfur-containing biomolecules include iron–sulfur clusters that act as cofactors for enzymes, sulfur-containing vitamins such as thiamin, and sulfur-modified nucleosides in RNA, in addition to methionine and cysteine in proteins. Sulfur-containing nucleosides are post-transcriptionally introduced into tRNA molecules, where they ensure precise ...
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Preparation of Yeast tRNA Sample for NMR Spectroscopy
Bio-Protocol, 2020 Transfer RNAs (tRNAs) are heavily decorated with post-transcriptional modifications during their biosynthesis. To fulfil their functions within cells, tRNAs undergo a tightly controlled biogenesis process leading to the formation of mature tRNAs.
Marjorie Catala +3 more
doaj +1 more source