Results 151 to 160 of about 55,541 (288)

Landscape of Post-Transcriptional tRNA Modifications in Streptomyces albidoflavus J1074 as Portrayed by Mass Spectrometry and Genomic Data Mining. [PDF]

J Bacteriol, 2023
Koshla O, Vogt LM, Rydkin O, Sehin Y, Ostash I, Helm M, Ostash B.   +6 more
europepmc   +1 more source

Rapid reconstruction of multidrug‐resistant bacterial genomes using CycloneSEQ nanopore sequencing

iMetaOmics, EarlyView.
Multidrug‐resistant (MDR) bacteria commonly harbor highly complex genomes enriched with mobile elements and resistance islands, which are challenging to resolve using short‐read sequencing. Here, we evaluated CycloneSEQ, a newly developed Chinese nanopore sequencing platform, for MDR genome reconstruction.
Kai Peng, Zeyu Tong, Changan Li, Zhichao Li, Xin Lu, Cemil Kurekci, Mashkoor Mohsin, Zhiqiang Wang, Yong‐Xin Liu, Ruichao Li   +9 more
wiley   +1 more source

Targeting metabolic rewiring might decrease spread of tumor cells: Mitochondrial tRNA modifications promote cancer metastasis. [PDF]

Signal Transduct Target Ther, 2022
Luu M, Visekruna A.
europepmc   +1 more source

Structure of tRNA Dimethylallyltransferase: RNA Modification through a Channel

, 2007
Wei Xie, Chun Zhou, Raven H. Huang
openalex   +2 more sources

Diversity, transfer potential, and transcriptional activity of virus‐carried antibiotic resistance genes in global estuaries

iMetaOmics, EarlyView.
Estuaries are vital hotspots for antibiotic resistance genes (ARGs) due to substantial antibiotic pollution. Although viruses have been proposed as key reservoirs and important disseminators of ARGs in environments, their contribution to the estuarine antibiotic resistome remains largely unknown.
Xiao‑Qing Luo, Xiyang Dong, Jia‑Ling Li, Ji‐Cheng Yao, Ziqi Peng, Qi Li, Zi‐Wen Yang, Yang Yuan, Wen‑Jun Li, Pandeng Wang   +9 more
wiley   +1 more source

Mutations in MTO2 Related to tRNA Modification Impair Mitochondrial Gene Expression and Protein Synthesis in the Presence of a Paromomycin Resistance Mutation in Mitochondrial 15 S rRNA

, 2005
Qingfeng Yan, Xiaoming Li, Gérard Faye, Min‐Xin Guan   +3 more
openalex   +1 more source

QutRNA2: Robust tRNA modification discovery from Nanopore direct tRNA sequencing

Abstract Transfer RNAs (tRNAs) are essential for protein synthesis and are extensively modified to ensure their structure and function. Direct RNA sequencing with Oxford Nanopore Technologies enables positional modification analysis but is challenged by tRNAs’ short length, redundancy, and dense modifications.
Michael Piechotta, Wei Guo, Isabel S. Naarmann-de Vries, Felix Kallenborn, Francesca Tuorto, Bertil Schmidt, Christoph Dieterich   +6 more
openaire   +1 more source

Probiotics‐derived postbiotics improve host metabolic syndrome by activating the adipocyte thermogenic signaling pathway in high‐fat diet‐fed mice

iMetaOmics, EarlyView.
This schematic illustrates how probiotics‐derived postbiotics (PLBK®1–5) combat high‐fat diet‐induced obesity. Postbiotics remodel gut microbiota, boosting beneficial metabolites. These metabolites activate adipocyte thermogenesis (Ucp1/AMPK pathway), resulting in reduced body weight, improved insulin sensitivity, and alleviated hepatic steatosis in ...
Ye Tian, Liujing Huang, Yifan Liu, Xudong Mai, Yanbo Cheng, Bingdong Liu, Yixin Chen, Liwei Xie   +7 more
wiley   +1 more source

Dynamic changes in tRNA modifications and abundance during T cell activation. [PDF]

Proc Natl Acad Sci U S A, 2021
Rak R, Polonsky M, Eizenberg-Magar I, Mo Y, Sakaguchi Y, Mizrahi O, Nachshon A, Reich-Zeliger S, Stern-Ginossar N, Dahan O, Suzuki T, Friedman N, Pilpel Y.   +12 more
europepmc   +1 more source

METTL1 promotes Neuroblastoma development through m 7 G tRNA modification and selective oncogenic gene translation [PDF]

, 2022
Ying Huang, Jieyi Ma, Cuiyun Yang, Paijia Wei, Minghui Yang, Hui Han, HuaDong Chen, Tianfang Yue, Shu Xiao, Xuanyu Chen, Zuoqing Li, Yan‐Lai Tang, Jie-Si Luo, Shuibin Lin, Libin Huang   +14 more
openalex   +1 more source