Results 191 to 200 of about 55,541 (288)

tRNA tK UUU , tQ UUG , and tE UUC wobble position modifications fine-tune protein translation by promoting ribosome A-site binding

open access: green, 2013
Vanessa Anissa Nathalie Rezgui   +7 more
openalex   +2 more sources

Inhibition of PHF1 promotes ferroptosis via IRES‐dependent Snail translation regulation in pancreatic ductal adenocarcinoma

open access: yesVIEW, EarlyView.
PHF1 is a known epigenetic regulator involved in transcriptional silencing in cancer. In this study, we identified PHF1 as an oncogene that promotes PDAC progression and demonstrated that its inhibition induces ferroptosis. Mechanistically, PHF1 physically interacts with the FBL/NOP56/NOP58 snoRNP complex to enhance the IRES‐dependent translation of ...
Yujiao Xie   +9 more
wiley   +1 more source

Russian wheat aphid: a model for genomic plasticity and a challenge to breeders

open access: yesInsect Science, EarlyView.
Invasive foundress finds suitable habitat and reproduces through pathogenesis. Wingless females produce life offspring quickly, which leads to high population densities. High population densities result in competition, which may induce epigenetic changes and wing development for dispersal.
Astrid Jankielsohn   +8 more
wiley   +1 more source

METTL1/WDR4-mediated m7G tRNA modifications and m7G codon usage promote mRNA translation and lung cancer progression. [PDF]

open access: yesMol Ther, 2021
Ma J   +12 more
europepmc   +1 more source

Fragment-based discovery of a new class of inhibitors targeting mycobacterial tRNA modification [PDF]

open access: gold, 2019
S.E. Thomas   +14 more
openalex   +1 more source

Full‐length transcriptome profiling of true bug mitochondrial genomes reveals the unique transcriptional regulation during insect evolution

open access: yesInsect Science, EarlyView.
The mitogenome was transcribed into complete primary polycistrons on both strands. The heteropteran mitochondrial transcription termination factor (HmTTF) functions as a bidirectional attenuator rather than a terminator, and co‐evolution of HmTTF and the binding sites was observed.
Shiwen Xu   +6 more
wiley   +1 more source

Editorial: tRNA and protein synthesis in microorganisms

open access: yesFrontiers in Microbiology
Matthieu G. Gagnon   +4 more
doaj   +1 more source

Home - About - Disclaimer - Privacy