Engineering a surrogate human heteromeric α/β glycine receptor orthosteric site exploiting the structural homology and stability of acetylcholine-binding protein [PDF]
Protein-engineering methods have been exploited to produce a surrogate system for the extracellular neurotransmitter-binding site of a heteromeric human ligand-gated ion channel, the glycine receptor.
Dawson, Alice +6 more
core +2 more sources
Selection of high berberine yielding phellodendron insulare nak. lines and the antimicrobial activity of their extracts [PDF]
High berberine yielding Phellodendron insulare Nak. lines were selected by aggregate cloning method and the antimicrobial activity of their extracts was assessed. The berberine producing cork tree lines were selected by adopting a colorimetric method. In
Chandrakant Karigar, S. +7 more
core +1 more source
Redirecting tropane alkaloid metabolism reveals pyrrolidine alkaloid diversity in Atropa belladonna. [PDF]
Parks HM +7 more
europepmc +1 more source
Conserved changes in dynamics of metabolic processes during fruit development and ripening across species [PDF]
Computational analyses of molecular phenotypes traditionally aim at identifying biochemical components that exhibit differential expression under various scenarios (e.g. environmental and internal perturbations) in a single species.
Drincovich, Maria Fabiana +7 more
core +2 more sources
Hyoscyamus niger have the main pharmaceutical tropane alkaloids and glycosides in their tissues. The study aimed to enhance the biosynthesis of these compounds by tissue culture techniques.
M. A. Khalaf, A. J. Taha, A. S. Abed
doaj +1 more source
Elucidation of tropane alkaloid biosynthesis in Erythroxylum coca using a microbial pathway discovery platform. [PDF]
Chavez BG +10 more
europepmc +1 more source
Novel psychoactive substances of interest for psychiatry [PDF]
Novel psychoactive substances include synthetic cannabinoids, cathinone derivatives, psychedelic phenethylamines, novel stimulants, synthetic opioids, tryptamine derivatives, phencyclidine-like dissociatives, piperazines, GABA-A/B receptor agonists, a ...
Corkery, John +3 more
core +1 more source
Hyoscyamine and scopolamine production in transformed root cultures of Datura metel L [PDF]
The transformed root cultures of Datura metel L (kecubung) was successfully established via Agrobacterium rhizogenes-mediated, which contained the pBI 121 plasmid harbouring the GUS and kanamycin coding genes.
Ahmad, Aziz
core
Differential expression of genes is key to mediating developmental and stress‐related plant responses. Here, we addressed the regulation of plant metabolic responses to biotic stress and the developmental variation of defense‐related genes in four ...
Eunice Kariñho Betancourt +5 more
doaj +1 more source
Background & Aim:A new sustainable tissue-based system is presented by plant hairy roots, preserving all of the several specialized types of cell with critical roles in allowing bioactive secondary molecules to be synthesized more consistently as usual ...
Ofelia Banihashemi +3 more
doaj +1 more source

