Results 91 to 100 of about 4,931 (220)

Engineering a surrogate human heteromeric α/β glycine receptor orthosteric site exploiting the structural homology and stability of acetylcholine-binding protein [PDF]

open access: yes, 2019
Protein-engineering methods have been exploited to produce a surrogate system for the extracellular neurotransmitter-binding site of a heteromeric human ligand-gated ion channel, the glycine receptor.
Dawson, Alice   +6 more
core   +2 more sources

Selection of high berberine yielding phellodendron insulare nak. lines and the antimicrobial activity of their extracts [PDF]

open access: yes, 2010
High berberine yielding Phellodendron insulare Nak. lines were selected by aggregate cloning method and the antimicrobial activity of their extracts was assessed. The berberine producing cork tree lines were selected by adopting a colorimetric method. In
Chandrakant Karigar, S.   +7 more
core   +1 more source

Redirecting tropane alkaloid metabolism reveals pyrrolidine alkaloid diversity in Atropa belladonna. [PDF]

open access: yesNew Phytol, 2023
Parks HM   +7 more
europepmc   +1 more source

Conserved changes in dynamics of metabolic processes during fruit development and ripening across species [PDF]

open access: yes, 2013
Computational analyses of molecular phenotypes traditionally aim at identifying biochemical components that exhibit differential expression under various scenarios (e.g. environmental and internal perturbations) in a single species.
Drincovich, Maria Fabiana   +7 more
core   +2 more sources

POTENTIAL OF CHEMICAL ELICITORS TO ENHANCE PRODUCTION SECONDARY METABOLITES IN INDUCED CALLUS FROM HYOSCYAMUS NIGER LEAVES

open access: yesThe Iraqi Journal of Agricultural science
Hyoscyamus niger have the main pharmaceutical tropane alkaloids and glycosides in their tissues. The study aimed to enhance the biosynthesis of these compounds by tissue culture techniques.
M. A. Khalaf, A. J. Taha, A. S. Abed
doaj   +1 more source

Elucidation of tropane alkaloid biosynthesis in Erythroxylum coca using a microbial pathway discovery platform. [PDF]

open access: yesProc Natl Acad Sci U S A, 2022
Chavez BG   +10 more
europepmc   +1 more source

Novel psychoactive substances of interest for psychiatry [PDF]

open access: yes, 2015
Novel psychoactive substances include synthetic cannabinoids, cathinone derivatives, psychedelic phenethylamines, novel stimulants, synthetic opioids, tryptamine derivatives, phencyclidine-like dissociatives, piperazines, GABA-A/B receptor agonists, a ...
Corkery, John   +3 more
core   +1 more source

Hyoscyamine and scopolamine production in transformed root cultures of Datura metel L [PDF]

open access: yes, 2000
The transformed root cultures of Datura metel L (kecubung) was successfully established via Agrobacterium rhizogenes-mediated, which contained the pBI 121 plasmid harbouring the GUS and kanamycin coding genes.
Ahmad, Aziz
core  

Comparative transcriptome profiling reveals distinct regulatory responses of secondary defensive metabolism in Datura species (Solanaceae) under plant development and herbivory‐mediated stress

open access: yesEcology and Evolution
Differential expression of genes is key to mediating developmental and stress‐related plant responses. Here, we addressed the regulation of plant metabolic responses to biotic stress and the developmental variation of defense‐related genes in four ...
Eunice Kariñho Betancourt   +5 more
doaj   +1 more source

In vitro production of secondary metabolite using Atropa komarovii Bline&Shal (Solanaceae) hairy root culture via Agrobacterium rhizogenes ATCC15834

open access: yesJournal of Herbal Drugs, 2017
Background & Aim:A new sustainable tissue-based system is presented by plant hairy roots, preserving all of the several specialized types of cell with critical roles in allowing bioactive secondary molecules to be synthesized more consistently as usual ...
Ofelia Banihashemi   +3 more
doaj   +1 more source

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