Ultrasonic Extraction of Tropane Alkaloids from Radix physochlainae Using as Extractant an Ionic Liquid with Similar Structure [PDF]
Molecules, 2019 In this research, tropane alkaloids in Radix physochlainae were extracted by tropine-type ionic liquid (IL) aqueous solutions under ultrasound assistance, and N-propyltropine hexafluorophosphate ([C3Tr][PF6]) was found to be the most ideal IL in this ...
Alula Yohannes +3 more
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A three-sided story: a biosystematic revision of genus Datura reveals novel tropane alkaloids for the first-time in certain species [PDF]
Frontiers in Plant ScienceIntroductionDatura, long considered an medicinal plant, represents a prospective source for discovering novel drugs for modern medicine. The Egyptian flora encompasses six Datura genotypes, including D. innoxia, D. ferox, D.
Abeer Al-Andal +8 more
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Engineering a microbial biosynthesis platform for de novo production of tropane alkaloids [PDF]
Nature Communications, 2019 Tropane alkaloids (TAs) are a group of phytochemicals that are used to treat neurological disorders. Here, the authors engineer baker’s yeast to produce tropine, a key intermediate in the biosynthetic pathway of TAs, and cinnamoyltropine, a non-canonical
Prashanth Srinivasan +1 more
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Tropane alkaloids biosynthesis involves an unusual type III polyketide synthase and non-enzymatic condensation [PDF]
Nature Communications, 2019 Tropane alkaloids are medicinally significant plant metabolites generated by an unusual condensation of ornithine-derived and malonyl-CoA precursors. Here, Huang et al. show that pyrrolidine ketide synthase catalyzes a single round of condensation, which
Jian-Ping Huang +8 more
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Bioorganic Chemistry, Toxinology, and Pharmaceutical Uses of Datura Metabolites and Derivatives [PDF]
ToxinsDatura species have been recognized for their potent pharmacological properties, producing a diverse array of tropane and non-tropane alkaloids with significant clinical and toxicological relevance.
Amin Mahmood Thawabteh +6 more
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Enhancing the accumulation of scopolamine and atropine in Hyoscyamus niger L. callus by LED light and glycine-a cheap method [PDF]
BMC Plant BiologyBackground The production of tropane alkaloids such as atropine and scopolamine by chemical methods is costly. This study aimed to find a more efficient method for producing tropane alkaloids by investigating different LED light qualities and glycine ...
Rasoul Heydarnajad Giglou +3 more
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Biosynthesis of medicinal tropane alkaloids in yeast [PDF]
Nature, 2020 Prashanth Srinivasan, Christina D Smolke
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Tropane alkaloids in mint teas at the Serbian market [PDF]
Agroznanje, 2021 The interest in tropane alkaloids as food contaminants has been increasing. The tropane alkaloids are plant toxins that mainly occur in Atropa, Datura and Hyoscyamus sp belonging to the Solanaceae family.
Vuković Gorica +7 more
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Global Biosecurity, 2023 In December 2022 a large outbreak of anti-cholinergic toxidrome was reported in Australia associated with contamination of baby spinach leaves with Datura stramonium. Over 100 individuals around Australia experienced symptoms consistent with intoxication
David Heslop
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The effect of methyljasmonate elicitor on tropan alkaloid production in hairy roots of Atropa belladonna [PDF]
مجله بیوتکنولوژی کشاورزی, 2017 The parasympatholytic tropane alkaloids, Atropine and Scopolamine, accumulated in Atropa belladonna, are of great interest for the pharmaceutical industry.In this research, Atropa belladonna transformed hairy roots were produced by Agrobacterium ...
M kHERADMAND +2 more
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