Results 31 to 40 of about 71,995 (193)

Synthesis and Pharmacological Evaluation of Psychoplastogenic Tropane Alkaloids and Analogs [PDF]

open access: yes, 2023
From the first reports of chewing coca leaves in 3000 B.C to the first isolation of atropine in 1832, tropane alkaloids are an integral class of natural products studied in chemistry, biology, and medicine.
Chow, Winston L
core   +1 more source

-demethylation of tropane alkaloids [PDF]

open access: yes, 2020
A practical, efficient, and selective electrochemicalN-demethylation method of tropane alkaloids to their nortropane derivatives is described. Nortropanes, such as noratropine and norscopolamine, are important intermediates for the semi-synthesis of the ...
Bischoff, Rainer   +13 more
core   +2 more sources

Tropane and Granatane Alkaloid Biosynthesis: A Systematic Analysis

open access: yesMolecules, 2016
The tropane and granatane alkaloids belong to the larger pyrroline and piperidine classes of plant alkaloids, respectively. Their core structures share common moieties and their scattered distribution among angiosperms suggest that their biosynthesis may
Neill Kim   +4 more
doaj   +1 more source

Advances in chemistry and bioactivity of the genus Erythroxylum

open access: yesNatural Products and Bioprospecting, 2022
Erythroxylum P. Browne is the largest and most representative genus of Erythroxylaceae family. It contains approximately 230 species that are mainly distributed in tropical and subtropical regions. Some species in this genus, such as E.
Yulian Lv   +4 more
doaj   +1 more source

Alkaloids Induce Programmed Cell Death in Bloodstream Forms of Trypanosomes (Trypanosoma b. brucei)

open access: yesMolecules, 2008
The potential induction of a programmed cell death (PCD) in Trypanosoma b. brucei by 55 alkaloids of the quinoline, quinolizidine, isoquinoline, indole, terpene, tropane, steroid, and piperidine type was studied by measuring DNA fragmentation and changes
Michael Wink, Vera Rosenkranz
doaj   +1 more source

Enhancing Tropane Alkaloid Production Based on the Functional Identification of Tropine-Forming Reductase in Scopolia lurida, a Tibetan Medicinal Plant

open access: yesFrontiers in Plant Science, 2017
Scopolia lurida, a native herbal plant species in Tibet, is one of the most effective producers of tropane alkaloids. However, the tropane alkaloid biosynthesis in this plant species of interest has yet to be studied at the molecular, biochemical, and ...
Kaihui Zhao   +13 more
doaj   +1 more source

Tropane alkaloids from Schizanthus porrigens [PDF]

open access: yes, 1998
Two new tropane alkaloids schizanthine Y and schizanthine Z have been isolated from the methanol extract of the leaves of Schizantus porrigens, in addition to the known compounds (-)-6β-angeloy-loxytropan-3α-ol and (-)-3α-senecioyloxytropan-6β-ol ...
Muñoz, O., Cortés, S.
core   +1 more source

Methylpyrrole Tropane Alkaloids from the Bark of Erythroxylum vacciniifolium [PDF]

open access: yes, 2005
Nine new tropane alkaloids substituted by a methylpyrrole moiety were isolated from the bark of Erythroxylum vacciniifolium, a Brazilian endemic plant used in traditional medicine and locally known as catuaba. All compounds were elucidated as tropanediol
Zanolari, Boris   +11 more
core   +1 more source

Quantitative analysis of total alkaloids by titration and Hyoscyamine by HPLC in indigenous Datur species inNorth of Iran [PDF]

open access: yesJournal of Mazandaran University of Medical Sciences, 2005
Background and purpose :.There are ten identified species of Datura in the world. Datura stramonium L. (Torn apple or Jimsonweed) and D.innoxia Mill. (Hindudatura) are endemic species of Datura in Iran, especially in the North (Caspian Sea region).
M. Azadbakht, S.M. Hoseinzadeh
doaj  

Application of Metabolic Engineering to the Production of Scopolamine

open access: yesMolecules, 2008
Scopolamine is an alkaloid widely used in medicine for its anticholinergic activity. The aim of this review is to show that metabolic engineering techniques constitute a suitable tool to improve the production of tropane alkaloids, focusing in particular
Mohammad Hossein Mirjalili   +3 more
doaj   +1 more source

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