Results 51 to 60 of about 867 (172)
The Interaction of the 5-HT3 Receptor with Arylpiperazine, Tropane, and Quinuclidine Ligands [PDF]
, 2002 The serotonin 5-HT(3) receptor subtype is unique among the receptors for this neurotransmitter because it has been demonstrated to be a ligand-gated ion channel capable of mediating rapid intercellular communication.
Cappelli, Andrea +15 more
core +1 more source
Synthesis and Evaluation of Calystegine B2 Analogues as Glycosidase Inhibitors [PDF]
, 2016 A practical synthesis of polyhydroxylated 6-oxa-nor-tropanes incorporating the essential structural features of calystegine B2 from 5-deoxy-5-thioureido and 5-ureido-l-idofuranose precursors is presented.
Juan M. Benito (1958092) +3 more
core +1 more source
Analysis of Binding Relationships between Cys-loop Receptors and Acetylcholine Binding Protein Mutants using Selective Tropane Triazole Compounds [PDF]
, 2015 [alpha]7 nAChRs and 5-HT3A receptors are important targets for potential theraupeutic treatments in pharmacological drug design. [alpha]7 nAChRs are implicated in CNS disorders such as Alzheimer's disease and schizophrenia, while 5-HT3A receptors are ...
Chen, Bill T.
core
Synthesis of novel biologically active tropanes [PDF]
, 1999 Diels-Alder cycloaddition between 1,3-cycloheptadiene (or its derivatives) and benzyl nitrosoformate produced intermediates from which the N-methyl-8-aza-bicyclo-[3.2.1]octane (tropane) ring system, 8-aza-bicyclo-[3.2.1]octane (nortropane) ring system ...
Anna L. Wallis (7631822)
core
PHYTOCHEMICAL AND PHARMACOLOGICAL STUDY OF DHATURA: A REVIEW [PDF]
, 2018 Dhatura is a well known medicinal plants belonging to solanaceae family and also known as devil’s trumpet or thorn apple. According to ayurvedic text it’s all part is used as medicinal drug and as a preparation with other drugs in various diseases ...
Anita, Sharma +2 more
core +1 more source
Structural studies of cyclic β-amino ketons using computational and NMR methods [PDF]
, 2015 Przestrzenna konfiguracja na atomie azotu w cyklicznych β-aminoketonach powoduje, że związki te mogą występować w dwóch stereoizomerycznych formach, w których podstawniki na tym atomie mogą przyjmować orientację aksjalną lub ekwatorialną w stosunku do ...
Łaźny, R., Sidorowicz, K.
core
Pharmacological Evaluation of Tropane Analogues at the Serotonin Transporter. [PDF]
ACS Chem NeurosciAvanes AA +3 more
europepmc +1 more source