Results 41 to 50 of about 928 (164)

Deciphering Cold Stress Resilience: Multiomics Insights in Contrasting Wheat Genotypes From the Western Himalayas

Plant Biotechnology Journal, Volume 24, Issue 7, Page 4577-4598, July 2026.
ABSTRACT Cold stress threatens wheat productivity, particularly in regions with extreme climatic conditions. To elucidate the molecular mechanisms underlying wheat's response to cold stress, we performed a multiomics analysis integrating lipidomics, transcriptomics, proteomics and metabolomics.
Sofora Jan, Farkhandah Jan, Mukesh Rathore, Yogita Singh, Prexha Kapoor, Palak Chaturvedi, Arindam Ghatak, Palakurthi Ramesh, Upendra Kumar, Manoj Prasad, Sundeep Kumar, Sachin Rustgi, Wolfram Weckwerth, Sanjay Kalia, Rajeev Kumar Varshney, Reyazul Rouf Mir   +15 more
wiley   +1 more source

The Early Response to Urea, Nitrate, or Ammonium and Iron Resupply in Tomato Roots Highlights the Induction of FER, bHLHs, UMAMITs, and MATEs

Physiologia Plantarum, Volume 178, Issue 4, July/August 2026.
ABSTRACT Depending on the nitrogen (N) form available to roots, plants activate different transcriptional and metabolic pathways; this can consequently translate into differences in the composition and release of root exudates. To address the existing knowledge gap regarding the relationship between the availability of Iron (Fe) and different N forms ...
Arianna Lodovici, Leilei Zhang, Nicola Tomasi, Gabriella Vinci, Fabio Marroni, Barbara Piani, Fatemeh Hassanvand, Mustapha Arkoun, Luigi Lucini, Laura Zanin   +9 more
wiley   +1 more source

Synthesis and Biological Evaluation of Tropane-like 1-{2-[Bis(4-fluorophenyl)methoxy]ethyl}-4-(3-phenylpropyl)piperazine (GBR 12909) Analogues

, 2016
We have prepared azabicyclo[3.2.1] derivatives (C-3-substituted tropanes) that bind with high affinity to the dopamine transporter and inhibit dopamine reuptake. Within the series, 3-{2-[bis-(4-fluorophenyl)methoxy]ethylidene}-8-methyl-8-azabicyclo[3.2.1]
Richard B. Rothman (354207), David B. Joseph (3012669), Wayne D. Bowen (2024014), Judith L. Flippen-Anderson (5752), Kenner C. Rice (1321671), Arthur E. Jacobson (1321668), Ying Zhang (1235337), Christina M. Dersch (354210)   +7 more
core   +1 more source

The Chemical Synthesis and Applications of Tropane Alkaloids

, 2019
Tropanes are an important class of alkaloid natural products that are found in plants all over the world. These compounds can exhibit significant biological activity and are among the oldest known medicines.
Wei-Wei Liao, Afewerki, Samson,, Armando Córdova, Samson Afewerki, Jia-Xin Wang, Cordova, Armando,, Liao, W. -W,, Wang, J. -X,   +7 more
core   +1 more source

Synthesis of N-(Hetero)arylconvolvine Derivatives through a Palladium-Catalyzed Buchwald–Hartwig Cross-Coupling

, 2019
International audienceThe present study describes the isolation of convolvine from the roots of the Tunisian plant Convolvulus dorycnium L. and it's synthesis through a four-steps sequence starting from tropine.
Ghermani, Noureddine, Hassine, Manel, Alami, Mouad, Jannet, Hichem Ben, Messaoudi, Samir   +4 more
core   +1 more source

New Regio- and Stereo­selective Cascades via Unstabilized Azomethine Ylide Cycloadditions for the Synthesis of Highly Substituted Tropane and Indolizidine Frameworks [PDF]

, 2016
Multisubstituted tropanes and indolizidines have been prepared with high regio- and stereo­selectivity by the [3+2] cycloaddition of unstabilized azo­methine ylides generated from readily prepared trimethylsilyl-substituted 1,2-dihydro­pyridines via ...
Robert G. Bergman (1323120), Jonathan A. Ellman, Mercado, Brandon Q, Tobias Knecht (3124821), Jonathan A. Ellman (610362), Ellman, Jonathan A, Shuming Chen (1590061), Brandon Q. Mercado, Vlad Bacauanu, Bacauanu, Vlad, Robert G. Bergman, Knecht, Tobias, Bergman, Robert G, Vlad Bacauanu (1819399), Chen, Shuming, Brandon Q. Mercado (1668904), Shuming Chen, Tobias Knecht   +17 more
core   +1 more source

Asymmetric Induction in C-Alkylation of Tropane-Derived Enamines: Congruence Between Computation and Experiment [PDF]

, 2017
Quantum chemical studies of C-ethylation of 1-methyl- and 1,4,4-trimethyl-tropane-derived enamines predict good (89:11 er, B3LYP) and high (98:2 er, B3LYP) levels, respectively, of asymmetric induction in the resulting α-alkylated aldehydes.
Heinrich-K. A. Rudy, Hodgson, David, Yifei Li, Paton, R, Kelvin E. Jackson, Rudy, H-KA, Ben Le Neve-Foster, Amber L. Thompson, Hodgson, DM, Asma Khurshid, Robert S. Paton, Charlton, A, Li, Y, Thompson, AL, Le Neve-Foster, B, David. M. Hodgson, Jackson, KE, Andrew Charlton, Khurshid, A   +18 more
core   +1 more source

Étude chimique et spectroscopique de la stéréochimie des quaternisations sur l'azote des tropanes

, 2019
Nous avons détermine le cours stérique préférentiel de la quaternisation des tropanes, dans le but de faciliter l'étude des effets physiologiques des sels quaternaires , étant donné la relation stéréochimie-activité pharmacologique.
Frehel, Daniel
core  

Discovery of new muscarinic acetylcholine receptor antagonists from Scopolia tangutica

, 2017
Scopolia tangutica (S. tangutica) is a traditional Chinese medicinal plant used for antispasmodics, anesthesia, analgesia and sedation. Its pharmacological activities are mostly associated with the antagonistic activity at muscarinic acetylcholine ...
Zhao, Jianqiang, Zhou, Han, Mei, Lijuan, Wang, Jixia, Liang, Xinmiao, He, Jian, Zhang, Xiuli, Liu, Yanfang, Du, Nana   +8 more
core   +2 more sources

APPLICATIONS OF ENANTIOPURE SULFINIMINE DERIVED CHIRAL AMINE BUILDING BLOCKS FOR THE ASYMMETRIC SYNTHESIS OF TROPANE ALKALOIDS AND CYCLIC CIS BETA-AMINO ACID DERIVATIVES

, 2011
Chiral amines are ubiquitous in natural products and are found in many drugs and drug candidates. Enantiopure sulfinimines [RS(O)N=CHR1] are useful chiral building blocks for the stereoselective synthesis of amines and amine derivatives.
Theddu, Naresh
core   +1 more source