Results 21 to 30 of about 928 (164)

Synthesis of novel biologically active tropanes

open access: yes, 1999
Diels-Alder cycloaddition between 1,3-cycloheptadiene (or its derivatives) and benzyl nitrosoformate produced intermediates from which the N-methyl-8-aza-bicyclo-[3.2.1]octane (tropane) ring system, 8-aza-bicyclo-[3.2.1]octane (nortropane) ring system ...
Anna L. Wallis (7631822)
core   +6 more sources

Quantitative results of incorporation of radiolabel (14C) from U-[14C]-sucrose into tropanes (tropine and pseudotropine) by rootless shoots (twigs) of W. somnifera.

open access: yes, 2013
Quantitative results of incorporation of radiolabel (14C) from U-[14C]-sucrose into tropanes (tropine and pseudotropine) by rootless shoots (twigs) of W. somnifera.
Amit Kumar Kushwaha (463088)   +5 more
core   +1 more source

Exploring Cervical Cancer‐Associated Vaginal and Cervical Microbiota via 16S rRNA Sequencing

open access: yesMicrobiologyOpen, Volume 15, Issue 5, October 2026.
This 16S sequencing study identified a dysbiotic cervical microbiota (increased diversity, reduced Lactobacillus, enriched Prevotella) specifically linked to high‐risk HPV infection. These microbial alterations, shaped by the HPV‐driven microenvironment, offer novel targets for biomarkers and mechanistic research in cervical carcinogenesis.
Guojiao Wang   +5 more
wiley   +1 more source

T2T Genome Assembly and Multi‐Omics Data Reveal Terrestrial Adaptation and Mucus Biosynthesis in Tropical Leatherleaf Slug (Laevicaulis alte)

open access: yesAdvanced Science, Volume 13, Issue 51, 14 September 2026.
A gap‐free genome assembly and multi‐omics comparison of the terrestrial slug Laevichaulis alte with an aquatic relative reveal that expansion of the VEGF family orchestrates mucus production, lipid metabolism, and immune defense—highlighting key molecular innovations for conquering life on land.
Gang Wang   +19 more
wiley   +1 more source

Enantioselective Synthesis of Functionalized Tropanes by Rhodium(II) Carboxylate-Catalyzed Decomposition of Vinyldiazomethanes in the Presence of Pyrroles

open access: yes, 2016
A series of enantiomerically enriched tropanes was synthesized by the rhodium(II) octanoate-catalyzed reaction of various N-BOC-protected pyrroles with vinyldiazomethanes.
Nicholas J. S. Huby (3010071)   +6 more
core   +1 more source

Systematic prioritization of candidate genes in camptothecin biosynthesis using multi‐omics and deep learning

open access: yesThe Plant Genome, Volume 19, Issue 3, September 2026.
Abstract Camptothecin (CPT), a plant‐derived monoterpene indole alkaloid first identified in Camptotheca acuminata, is a drug precursor widely used for cancer chemotherapeutics. However, the full set of genes responsible for CPT biosynthesis remains unclear, hindering efforts to elucidate the complete pathway or establish biosynthetic production of CPT
Shenqi Wang   +6 more
wiley   +1 more source

Synthesis, Monoamine Transporter Binding Properties, and Behavioral Pharmacology of a Series of 3β-(Substituted phenyl)-2β-(3‘-substituted isoxazol-5-yl)tropanes

open access: yes, 2016
Several 3β-(substituted phenyl)-2β-(3-substituted isoxazol-5-yl)tropanes (3a−t) were evaluated for their ability to inhibit radioligand binding at the DAT, 5-HTT, and NET as well as in gross observation and locomotor activity in mice and in rats trained ...
Gerald T. Pollard (2283136)   +4 more
core   +1 more source

Multi‐omics insights into salinity tolerance in African bermudagrass

open access: yesThe Plant Genome, Volume 19, Issue 3, September 2026.
Abstract African bermudagrass (Cynodon transvaalensis Burtt‐Davy) is a key parent species used to produce interspecific hybrid bermudagrass (Cynodon dactylon × C. transvaalensis). Due to the increasing use of non‐potable water for landscape irrigation, salt stress has become a major concern in the turfgrass industry.
Prabha Adhikari   +7 more
wiley   +1 more source

Ipvelutine, 7β-acetoxy-2α-(tigloyloxy)tropane, an unusual tropane alkaloid from Ipomoea velutina R. BR. (Convolvulaceae) [PDF]

open access: yes, 2013
Convolvulaceae provide a rich source of tropane alkaloids, however, 2-substi-tuted tropanes have been described for only few species of this taxon.
Eich, Eckart   +5 more
core   +1 more source

Persistent Epigenetic Reprogramming Is Associated With Contrasting Drought‐Response Strategies in Citrus Scion–Rootstock Systems

open access: yesPhysiologia Plantarum, Volume 178, Issue 5, September/October 2026.
ABSTRACT Recurrent drought limits the productivity of perennial crops such as citrus, whose tolerance to water deficit largely depends on scion–rootstock interactions. Although physiological responses to recurrent drought are well documented, the epigenetic states associated with these responses remain poorly understood, limiting the use of epigenetic ...
Monique Ayala Araújo da Silva   +8 more
wiley   +1 more source

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