Results 121 to 130 of about 109,495 (390)
A Critical Role of TET1/2 Proteins in Cell-Cycle Progression of Trophoblast Stem Cells
Stem Cell Reports, 2018 Summary: The ten-eleven translocation (TET) proteins are well known for their role in maintaining naive pluripotency of embryonic stem cells. Here, we demonstrate that, jointly, TET1 and TET2 also safeguard the self-renewal potential of trophoblast stem ...
Stephanie Chrysanthou +7 more
doaj
International Journal of Gynecology &Obstetrics, EarlyView.Abstract Objective To evaluate the ability of the fullPIERS model to predict adverse maternal outcomes in patients diagnosed as early‐onset pre‐eclampsia at Charlotte Maxeke Johannesburg Academic Hospital, South Africa. Methods Retrospective record review and analysis of 134 patients admitted with early‐onset pre‐eclampsia.
Thomas Matonhodze, Robert Nyakoe
wiley +1 more source
PLoS Biology, 2019 Multipotent trophoblasts undergo dynamic morphological movement and cellular differentiation after conceptus implantation to generate placenta. However, the mechanism controlling trophoblast development and differentiation during peri-implantation ...
Bo Lv +9 more
semanticscholar +1 more source
International Journal of Gynecology &Obstetrics, EarlyView.Abstract Background Gestational diabetes mellitus (GDM) can result in increased placental lesions related to high maternal blood glucose, but these relationships are not well understood. Objective To examine the relationship between GDM and placental vascular malperfusion lesions: accelerated villous maturation, increased syncytial knots, delayed ...
Amrita Arcot +4 more
wiley +1 more source
Scientific Reports, 2019 Trophoblast oxidative phosphorylation provides energy for active transport and protein synthesis, which are critical placental functions influencing fetal growth and long-term health.
Fredrick J Rosario +6 more
semanticscholar +1 more source
The Fetal Allograft Revisited: Does the Study of an Ancient Invertebrate Species Shed Light on the Role of Natural Killer Cells at the Maternal-Fetal Interface? [PDF]
, 2008 Human pregnancy poses a fundamental immunological problem because the placenta and fetus are genetically different from the host mother. Classical transplantation theory has not provided a plausible solution to this problem.
Barrier, Breton F. +3 more
core +6 more sources
A Gelatin Hydrogel to Study Endometrial Angiogenesis and Trophoblast Invasion
bioRxiv, 2019 As the lining of the uterus and site of blastocyst implantation, the endometrium is a dynamic tissue that undergoes rapid cycles of growth, breakdown, and remodeling each menstrual cycle.
Samantha G. Zambuto +2 more
semanticscholar +1 more source
Unique trophoblast chromatin environment mediated by the PcG protein SFMBT2
Biology Open, 2019 Stem/progenitor cells are maintained by a chromatin environment, mediated in part by Polycomb group (PcG) proteins, which depress differentiation.
Priscilla Tang +2 more
doaj +1 more source
The impact and management of hyperemesis gravidarum: Current and future perspectives
International Journal of Gynecology &Obstetrics, EarlyView.Abstract Hyperemesis gravidarum (HG) is a severe form of nausea and vomiting in pregnancy affecting around 1%–3% of pregnancies worldwide and is the most common reason for hospital admission in early pregnancy. HG can have lasting consequences for both pregnant individuals and their offspring.
L. M. van der Minnen +4 more
wiley +1 more source
Molecular human reproduction, 2019 Human umbilical cord mesenchymal stem cells (MSCs) have been reported to improve the migration and invasion of trophoblast cells; however, little is known about whether MSC-derived exosomes and exosomal miRNAs can regulate trophoblast cell properties. In
Changwon Yang +5 more
semanticscholar +1 more source