Results 121 to 130 of about 87,349 (342)

Gestational Trophoblastic Neoplasia

CA: A Cancer Journal for Clinicians, 1981
As a result of modern diagnostic and therapeutic techniques, nearly 100 percent of patients with GTN can be cured of a disease thay only a few years ago had a high death rate. To achieve this, skillful mixing of chemotherapy, surgery, and irradiation, as well as supportive therapy, are necessary.
C B, Hammond, J C, Weed, D E, Barnard, L, Tyrey   +3 more
openaire   +2 more sources

Human trophoblast invasion: new and unexpected routes and functions

Histochemistry and Cell Biology, 2018
Until recently, trophoblast invasion during human placentation was characterized by and restricted to invasion into uterine connective tissues and the uterine spiral arteries.
G. Moser, Karin Windsperger, J. Pollheimer, S. D. S. de Sousa Lopes, B. Huppertz   +4 more
semanticscholar   +1 more source

Optimizing the integration of modern systemic therapies and advanced radiotherapy techniques in breast cancer management: An expert opinion from the Institut Curie Breast Radiotherapy Group

International Journal of Cancer, EarlyView.
Abstract The integration of modern systemic therapies with radiotherapy (RT) represents a promising strategy in breast cancer management, enhancing both locoregional control and systemic disease outcomes. This expert consensus from the Institut Curie Breast Radiotherapy Group focuses exclusively on modern systemic agents, synthesizing current evidence ...
Cezara Cheptea, Pierre Loap, Sofiane Allali, Alain Fourquet, Kim Cao, Youlia Kirova   +5 more
wiley   +1 more source

Anti-inflammatory effects of mesenchymal stem cell-derived exosomal microRNA-146a-5p and microRNA-548e-5p on human trophoblast cells.

Molecular human reproduction, 2019
Human umbilical cord mesenchymal stem cells (MSCs) have been reported to improve the migration and invasion of trophoblast cells; however, little is known about whether MSC-derived exosomes and exosomal miRNAs can regulate trophoblast cell properties. In
Changwon Yang, W. Lim, Junghyung Park, Sunwoo Park, Seungkwon You, G. Song   +5 more
semanticscholar   +1 more source

Vascular dysfunction in women with recurrent pregnancy loss: Possible association with antiphospholipid antibodies

International Journal of Gynecology &Obstetrics, Volume 169, Issue 1, Page 206-214, April 2025.
Abstract Objective Antiphospholipid antibodies (aPL) are recognized to have a pivotal role in recurrent pregnancy loss (RPL) and cardiovascular disease. Therefore, we assessed the vascular function of women with RPL and examined the association with each type of aPL.
Titi Yang, Emi Okada, Maho Todoroki, Siyu Liu, Rukmali Athurupana, Kumie Kataoka, Chiaki Kashino, Takashi Mitsui, Toru Hasegawa, Yasuhiko Kamada, Hisashi Masuyama, Mikiya Nakatsuka   +11 more
wiley   +1 more source

Uncovering the role of genetic polymorphisms in cervical insufficiency

International Journal of Gynecology &Obstetrics, EarlyView.
Pathways and genes implicated in CI pathogenesis. Abstract Cervical insufficiency (CI) is characterized by spontaneous dilation of the cervix in the absence of painful uterine contractions in the mid‐trimester, leading to premature delivery. It is responsible for up to 20% of second trimester pregnancy losses, mostly <24 weeks.
Kallirhoe Kalinderi, Michail Kalinderis, Maria Chatzidimitriou, Liana Fidani   +3 more
wiley   +1 more source

Factors affecting the umbilical artery Doppler reference values in the second and third trimesters

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective To explore the contribution of selected methodological factors to the heterogeneity in published umbilical artery pulsatility index (UA‐PI) reference charts. Methods Cross‐sectional study of uncomplicated singleton pregnancies that underwent assessment of UA Doppler at a single center.
Sophia Rahimi, John C. Kingdom, Arietta Vayenas, Vasilica Stratulat, Nir Melamed   +4 more
wiley   +1 more source

Immunohistochemical Examination of Trophoblast Syncytialization during Early Placentation in Sheep

International Journal of Molecular Sciences, 2019
During the peri-implantation period, multinucleated syncytia are formed in the sheep placenta. For over 20 years the scientific consensus has been that during trophoblast syncytialization in sheep, binucleate trophoblast giant cells (BNCs) differentiate ...
H. Seo, F. Bazer, R. Burghardt, G. Johnson   +3 more
semanticscholar   +1 more source

Gestational trophoblastic disease [PDF]

BMJ, 1997
The term gestational trophoblastic disease includes hydatidiform moles, invasive hydatidiform moles, and choriocarcinoma. However, many gynaecologists and oncologists seem to consider that these conditions represent a neoplastic spectrum, with moles at the benign end, choriocarcinoma at the malignant extreme, and invasive hydatidiform moles being ...
openaire   +2 more sources

Human placental trophoblast cells contribute to maternal–fetal tolerance through expressing IL-35 and mediating iTR35 conversion

Nature Communications, 2019
During pregnancy, trophoblast cells sustain the maternal–fetal tolerance via expressing and secreting various chemokines and cytokines. Our previous study revealed the expression of interleukin-35 (IL-35) in human first-trimester trophoblasts.
Jia Liu, Shengnan Hao, Xi Chen, Hui Zhao, Lutao Du, Hanxiao Ren, Chuanxin Wang, H. Mao   +7 more
semanticscholar   +1 more source