Results 201 to 210 of about 109,495 (390)

Mesenchymal Stem Cell‐Derived Exosomes: A Promising Therapeutic Strategy for Age‐Related Diseases

open access: yesCell Proliferation, EarlyView.
Mechanisms of MSC‐Exos in the treatment of age‐related diseases. A Immunomodulatory and anti‐inflammatory, MSC‐Exos mediate immunomodulatory and anti‐inflammatory effects by regulating the polarisation of T cells and macrophages, promoting an anti‐inflammatory state while inhibiting pro‐inflammatory responses; B Suppression of oxidative stress, MSC ...
Bohua Wei   +5 more
wiley   +1 more source

Mitonuclear Communication in Stem Cell Function

open access: yesCell Proliferation, EarlyView.
In this review, we highlight the critical functions of mitonuclear communication and its impact on mitochondrial proteostasis. Additionally, we examine how mitonuclear signalling influences stem cell function, offering new insights into cellular homeostasis, stem cell therapies, and the potential for lifespan extension.
Baozhou Peng, Yaning Wang, Hongbo Zhang
wiley   +1 more source

Genetically Engineered Hypoimmune Human Muscle Progenitor Cells Can Reduce Immune Rejection

open access: yesCell Proliferation, Volume 58, Issue 4, April 2025.
Cells face two challenges after transplantation: recognition and killing by lymphocytes, and cell apoptosis induced by the transplantation environment. Our hypoimmune cells aim to address these two challenges through editing of immunomodulatory proteins and overexpression of anti‐apoptotic proteins.
Yu Chen   +8 more
wiley   +1 more source

The transcriptional regulatory network modulating human trophoblast stem cells to extravillous trophoblast differentiation

open access: yesNature Communications
During human pregnancy, extravillous trophoblasts play crucial roles in placental invasion into the maternal decidua and spiral artery remodeling.
Mijeong Kim   +8 more
doaj   +1 more source

66 PURINE NUCLEOTIDE SUPPLY OF THE HUMAN TROPHOBLAST [PDF]

open access: bronze, 1988
Kim Vettenranta, Kari O. Raivio
openalex   +1 more source

Organoids in Haematologic Research: Advances and Future Directions

open access: yesCell Proliferation, EarlyView.
This review focuses on the advancements in organoid technology and its transformative role in haematological research, particularly in the modelling of haematopoietic tissues, blood diseases and drug development. It also offers an outlook on the future prospects of organoids in personalised medicine and the study of disease mechanisms.
Liangzheng Chang   +4 more
wiley   +1 more source

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