Results 71 to 80 of about 3,985 (199)

Excessive hypercholesterolaemia during pregnancy as a risk factor for endothelial dysfunction in pre‐eclampsia

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Excessive hypercholesterolaemia during pregnancy impairs maternal endothelial function, which, in turn, drives the development of pre‐eclampsia and may also contribute to the increased risk of later‐life cardiovascular disease in women.
Amanda A. de Oliveira   +3 more
wiley   +1 more source

Germ cell and other tumors in individuals with differences in sex development

open access: yesCA: A Cancer Journal for Clinicians, EarlyView.
Abstract Approximately one in 3500 to one in 5100 live‐born infants have atypical external genital development, known as differences in sex development (DSD). In 2005, an expert consensus conference thoroughly reviewed aspects of health care for individuals with DSD.
Selma Feldman Witchel   +1 more
wiley   +1 more source

Identification of Tumor‐Specific Surface Proteins Enables Quantification of Extracellular Vesicle Subtypes for Early Detection of Pancreatic Ductal Adenocarcinoma

open access: yesAdvanced Science, Volume 12, Issue 21, June 5, 2025.
Pancreatic ductal adenocarcinoma (PDAC) extracellular vesicle (EV) surface protein assay operates via a two‐step workflow – Step 1: Click chemistry‐mediated enrichment of PDAC EVs by EV Click Beads, in the presence of one of the three trans‐cyclooctene‐grafted PDAC EV‐specific antibodies; Step 2: Quantification of the enriched PDAC EVs by reverse ...
Chen Zhao   +27 more
wiley   +1 more source

Circulating Tumor Cell Detection for Therapeutic and Prognostic Roles in Breast Cancer

open access: yesCancer Medicine, Volume 14, Issue 11, June 2025.
The figure outlines the process of tumor cell migration, the samples available for testing and the classification of enrichment assays, and the use of circulating cells. CSF: cerebrospinal fluid‐derived circulating tumor cell, CTC: circulating tumor cell, CTEC: circulating tumor endothelial cell, DTC: disseminated tumor cell, MRD: minimal residual ...
Saiying Ma   +3 more
wiley   +1 more source

Endometriosis‐derived exosomes encapsulated miR‐196a‐5p mediate macrophage polarization through regulation of the Hippo pathway

open access: yesJournal of Cell Communication and Signaling, Volume 19, Issue 2, June 2025.
Encapsulation of miR‐196a‐5p mimic in serum‐derived exosomes from patients with endometriosis by electrotransfection: exosomes encapsulated with miR‐196a‐5p are phagocytosed by macrophages and release miR‐196a‐5p; miR‐196a‐5p activates the Hippo pathway and promotes macrophage M1‐type polarization, thereby inhibiting 12Z cell metastasis.
Bin Lu, Qixiang Huang, Yanyu Zhong
wiley   +1 more source

MicroRNA‐371–373 cluster and methylome analysis suggests that a subset of ‘somatic‐type’ malignancies arising in germ cell tumors may originate in yolk sac tumor components

open access: yesThe Journal of Pathology, Volume 266, Issue 2, Page 160-176, June 2025.
Abstract Somatic‐type malignancies (SMs) arising in germ cell tumors (GCTs) are aggressive neoplasms resistant to systemic treatment. Most are diagnosed in metastatic sites after chemotherapy; however, they have also been well‐documented in primary testicular GCTs.
João Lobo   +17 more
wiley   +1 more source

Neuropsychological Performance and Its Predictors in the Early Treatment Phase of Non‐CNS Pediatric Cancer

open access: yesPediatric Blood &Cancer, Volume 72, Issue 6, June 2025.
ABSTRACT Background Pediatric cancer survivors can experience neuropsychological problems in the long term. Less is known about neuropsychological performance and its possible predictors in the early treatment phase of non‐central nervous system (CNS) cancers.
Marisa H. Huisman   +6 more
wiley   +1 more source

Artificial Intelligence for Organoids Multidimensional Assessment

open access: yesSmartMat, Volume 6, Issue 3, June 2025.
This review provides a comprehensive analysis and discussion of the current applications of artificial intelligence (AI) technologies in the evaluation of organoids. It summarizes and synthesizes the primary methods and standards for organoid assessment, offering new insights for researchers engaged in the interdisciplinary field of AI and organoid ...
Yulin Mo   +5 more
wiley   +1 more source

Gestational choriocarcinoma presenting with uterine rupture and shock: a case report [PDF]

open access: yes
The aim of the study was to report an extremely rare case of gestational choriocarcinoma with a ruptured uterus, its early manifestations and management.
Babu, Sandhya, Sharma, Vinutha M.
core   +2 more sources

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