Results 91 to 100 of about 95,222 (302)

Phenotypic and Genotypic Features of Macrophage Tropism in HIV-1 [PDF]

, 2016
HIV-1 preferentially attaches and enters specific cell types by recognizing cell-specific receptors. HIV-1 typically targets memory CD4+ T cells by restricting attachment to cells expressing high CD4 densities and by using the CCR5 coreceptor.
Arrildt, Kathryn
core   +1 more source

Engineering a 660 nm‐Responsive Optogenetic Inducer of Pyroptosis for Precision Cancer Therapy

Advanced Science, EarlyView.
This study reports a bioorthogonal pyroptosis inducer, PyroRACS. By using a red‐light‐responsive Cre‐On genetic switch to control the expression of highly cytotoxic GSDMDNT, PyroRACS enables the artificial induction of pyroptosis with precise spatiotemporal control.
Mengkai Zhang, Zhichao Li, Yonghao Ma, Yangyang Sun, Wei Chen, Weiren Huang   +5 more
wiley   +1 more source

WU Polyomavirus in Respiratory Epithelial Cells from Lung Transplant Patient with Job Syndrome

Emerging Infectious Diseases, 2015
We detected WU polyomavirus (WUPyV) in a bronchoalveolar lavage sample from lungs transplanted into a recipient with Job syndrome by using immunoassays specific for the WUPyV viral protein 1.
Erica A. Siebrasse, Diana V. Pastrana, Nang L. Nguyen, Annie Wang, Mark J. Roth, Steven M. Holland, Alexandra F. Freeman, John McDyer, Christopher B. Buck, David Wang   +9 more
doaj   +1 more source

Pitfalls of HIV genotypic tropism testing after treatment interruption

, 2013
Item does not contain fulltextOBJECTIVES: The genotypic method is reliable enough for the determination of tropism and largely preferred in Europe. However, careful interpretation is essential when assessing HIV genotypic resistance during treatment ...
Calvez, V., Marcelin, A.G., Fourati, S., Soulie, C., Simon, A., Schneider, L., Wirden, M., Tubiana, R., Bonmarchand, M., Valantin, M.A., Katlama, C., Ktorza, N.   +11 more
core   +1 more source

Decreased HIV diversity after allogeneic stem cell transplantation of an HIV-1 infected patient : a case report [PDF]

, 2010
The human immunodeficiency virus type 1 (HIV-1) coreceptor use and viral evolution were analyzed in blood samples from an HIV-1 infected patient undergoing allogeneic stem cell transplantation (SCT).
Bravo Ignacio G, Wolf, Timo, Schnierle Barbara S, Schnierle, Barbara S, Thielen, A., Krause, B., Werner, A., Schnierle, Barbara, Christel Kamp, Bravo, I., Winskowsky, Gudrun, Albrecht Werner, Neumann, B., Thielen, Alexander, Werner Albrecht, Krause Birgit, Kamp Christel, Timo Wolf, Wolf, T., Thielen Alexander, Winskowsky, G., Kraus, Benjamin, Wolf Timo, Werner, Albrecht, Gudrun Winskowsky, Alexander Thielen, Neumann, Britta, Birgit Krause, Bravo, Ignacio G., Neumann Britta, Kraus, B., Kamp, Christel, Kamp, C., Ignacio G Bravo, Barbara S Schnierle, Krause, Birgit, Bravo, Ignacio G, Winskowsky Gudrun, Kraus Benjamin, Britta Neumann, Schnierle, B., Benjamin Kraus   +41 more
core   +1 more source

Sulfated Glycosaminoglycans as Viral Decoy Receptors for Human Adenovirus Type 37

Viruses, 2019
Glycans on plasma membranes and in secretions play important roles in infection by many viruses. Species D human adenovirus type 37 (HAdV-D37) is a major cause of epidemic keratoconjunctivitis (EKC) and infects target cells by interacting with sialic ...
Naresh Chandra, Yan Liu, Jing-Xia Liu, Lars Frängsmyr, Nian Wu, Lisete M Silva, Mona Lindström, Wengang Chai, Fatima Pedrosa Domellöf, Ten Feizi, Niklas Arnberg   +10 more
doaj   +1 more source

Block of death-receptor apoptosis protects mouse cytomegalovirus from macrophages and is a determinant of virulence in immunodeficient hosts. [PDF]

, 2012
The inhibition of death-receptor apoptosis is a conserved viral function. The murine cytomegalovirus (MCMV) gene M36 is a sequence and functional homologue of the human cytomegalovirus gene UL36, and it encodes an inhibitor of apoptosis that binds to ...
Ebermann, L., Čičin-Šain, Luka, Luka Čičin-Šain, Rosaely Casalegno-Garduño (111456), Carlos A Guzmán, Ruzsics, Zsolt, van Rooijen, Nico, Koszinowski, U., van Rooijen, N., Ulrich Koszinowski, Linda Ebermann (111451), Zsolt Ruzsics (75383), Ruzsics, Z., Nico van Rooijen, Guzman, C.A., Casalegno-Garduno, R., Ulrich Koszinowski (111457), Ruzsics Zsolt, Casalegno-Garduño, Rosaely, Nico van Rooijen (4110211), Koszinowski, Ulrich H., Zsolt Ruzsics, Carlos A. Guzmán (111454), Luka Čičin-Šain (111459), Guzmán, Carlos A., Rooijen, N. van, Guzmán Carlos A., Ebermann Linda, Linda Ebermann, Cicin-Sain, L., Čičin-Šain Luka, Guzmán, Carlos A, Casalegno-Garduño Rosaely, Koszinowski, Ulrich, Rosaely Casalegno-Garduño, Ebermann, Linda, van Rooijen Nico, Koszinowski Ulrich   +37 more
core   +2 more sources

Engineering Morphological Anisotropy to Control the In Vivo Transport Dynamics, Clearance, and Biodistribution of Silica Nanocarriers

Advanced Science, EarlyView.
Morphological anisotropy directs the in vivo transport under physiological flow and clearance of silica nanocarriers. Increasing anisotropy reduces cellular uptake, suppresses hepatic and splenic sequestration, and prolongs systemic circulation by steering particles toward the central flow core.
Xiaofei Li, Yingjie Yu, Tianchang He, Xiaoyan Fang, Wenhua Yang, Luying Zhou, Hao Fan, Guimei Lin, Daniel Crespy, Katharina Landfester, Junfeng Zhang, Shuai Jiang   +11 more
wiley   +1 more source

Viral Tropism [PDF]

Frontiers in Microbiology, 2012
Nomaguchi, Masako, Fujita, Mikako, Miyazaki, Yasuyuki, Adachi, Akio   +3 more
openaire   +3 more sources

The Dual Tropism of Noroviruses [PDF]

Journal of Virology, 2018
Noroviruses are highly prevalent enteric RNA viruses. Human noroviruses (HuNoVs) cause significant morbidity, mortality, and economic losses worldwide.
openaire   +2 more sources