Results 41 to 50 of about 7,724 (232)

Heparan sulphate interacts with tropoelastin, with some tropoelastin peptides and is present in human dermis elastic fibers

Matrix Biology, 2005
A number of reports point to the presence of proteoglycans and/or glycosaminoglycans within elastic fibers in normal and in pathological conditions. We present data that heparan sulphate (HS)-containing proteoglycans are associated with normal elastic fibers in human dermis and that isolated HS chains interact in vitro with recombinant tropoelastin and
Dealba Gheduzzi, Deanna Guerra, Brigida Bochicchio, Antonietta Pepe, Antonio Mario Tamburro, Daniela Quaglino, Suzanne M. Mithieux, Anthony S. Weiss, Ivonne Pasquali Ronchetti   +8 more
openalex   +5 more sources

Silk–tropoelastin protein films for nerve guidance [PDF]

Acta Biomaterialia, 2014
Peripheral nerve regeneration may be enhanced through the use of biodegradable thin film biomaterials as highly tuned inner nerve conduit liners. Dorsal root ganglion neuron and Schwann cell responses were studied on protein films comprising silk fibroin blended with recombinant human tropoelastin protein.
James D. White, Siran Wang, Anthony S. Weiss, David L. Kaplan   +3 more
openalex   +3 more sources

Elastin is Localised to the Interfascicular Matrix of Energy Storing Tendons and Becomes Increasingly Disorganised With Ageing [PDF]

, 2017
Tendon is composed of fascicles bound together by the interfascicular matrix (IFM). Energy storing tendons are more elastic and extensible than positional tendons; behaviour provided by specialisation of the IFM to enable repeated interfascicular sliding
A Heinz, AJ Viera, B Vrhovski, C Thorpe, C Thorpe, CT Thorpe, CT Thorpe, CT Thorpe, CT Thorpe, CT Thorpe, CT Thorpe, D Bedell-Hogan, EL Batson, F Ramirez, H Birch, H Oxlund, H Tempfer, HL Birch, IM Braverman, J Fallon, JA Foster, JA Foster, JA Pierce, JE Wagenseil, JF Innes, K Kubo, KD Smith, L Nimeskern, L Robert, L Robert, M Akagawa, M Benjamin, M Luisetti, MJ Sherratt, P Berens, P Kannus, PPY Lui, R Alexander, R Ker, SA Fenwick, SE Greenwald, SG Dakin, T Watanabe, TB Csóka, TC Lee, TM Grant, TM Grant, Z Gunja-Smith, Z Liu   +48 more
core   +4 more sources

Elastogenic protein expression of a highly elastic murine spinal ligament: the ligamentum flavum. [PDF]

PLoS ONE, 2012
Spinal ligaments, such as the ligamentum flavum (LF), are prone to degeneration and iatrogenic injury that can lead to back pain and nerve dysfunction. Repair and regeneration strategies for these tissues are lacking, perhaps due to limited understanding
Jeffrey P Brown, Rachel M Lind, Anthony F Burzesi, Catherine K Kuo   +3 more
doaj   +1 more source

The changes in chemical composition during development of the bovine nuchal ligament [PDF]

, 1967
Whole bovine nuchal ligaments, or portions thereof (in the case of commercially valuable animals), were obtained from 45 animals (28 fetal and 17 postnatal) ranging in age from 110 days of gestation to 10 yr. Insoluble elastin was quantitatively prepared
Cleary, E. G., Jackson, D. S., Sandberg, L. B.   +2 more
core   +3 more sources

Multiple chick tropoelastin mRNAs

Biochemical and Biophysical Research Communications, 1988
Several overlapping chick tropoelastin cDNAs were isolated from a lambda gt11 cDNA library constructed from whole 10 day chick embryo total RNA. Comparison of the nucleotide sequence of the 2.3 kb tropoelastin cDNA to the sequences published by Bressan et al. (1) and Tokimitsu et al.
V J, Baule, J A, Foster
openaire   +2 more sources

Coacervation Characteristics of Recombinant Human Tropoelastin [PDF]

European Journal of Biochemistry, 1997
Coacervation of soluble tropoelastin molecules is characterized by thermodynamically reversible association as temperature is increased under appropriately juxtaposed ionic conditions, protein concentration and pH. Coacervation plays a critical role in the assembly of these elastin precursors in elastic fiber formation.
B, Vrhovski, S, Jensen, A S, Weiss
openaire   +2 more sources

Electrospun ECM macromolecules as biomimetic scaffold for regenerative medicine: challenges for preserving conformation and bioactivity [PDF]

, 2017
The extracellular matrix (ECM), the physiological scaffold for cells in vivo, provides structural support to cells and guaranties tissue integrity. At the same time, however, it represents an extremely complex and finely tuned signaling environment that ...
CAMPIGLIO, CHIARA EMMA, DRAGHI, LORENZA, MARCOLIN, CHIARA   +2 more
core   +2 more sources

Perinatal expression of genes that may participate in lipid metabolism by lipid-laden lung fibroblasts

Journal of Lipid Research, 1998
Although a morphologically distinct population of lipid-laden interstitial cells (lipofibroblasts, LF), has been identified, the origins and functions of this population during lung development and disease remain undefined.
Heshun Chen, Sheila Jackson, Melissa Doro, Stephen McGowan   +3 more
doaj   +1 more source

Arterial stiffening in western diet-fed mice is associated with increased vascular elastin, transforming growth factor-ß, and plasma neuraminidase [PDF]

, 2016
Consumption of excess fat and carbohydrate (Western diet, WD) is associated with alterations in the structural characteristics of blood vessels. This vascular remodeling contributes to the development of cardiovascular disease, particularly as it affects
Alvira, Aneja, Arribas, Baydanoff, Bender, Billaud, Bizbiz, Blaise, Boak, Briones, Carlson, Castorena-Gonzalez, Clifford, Dantas, Davis, de Onis, DeMarco, Duprez, Emoto, George, Guilherme, Heinemann, Hinek, Hinek, Horiguchi, Huxley, Jia, Jung, Katz, Kielty, Kielty, Kuang, Kucich, Kucich, Kwon, Ledoux, Lesniewski, Majane, Martinez-Lemus, Matthews, McGill, McGowan, Mulvany, Nicoloff, Nistala, Parikh, Payne, Pennington, Roozbeh, Sandow, Sehgel, Shen, Souza-Smith, Sproul, Stehouwer, Stolarczyk, Straub, Sutton-Tyrrell, Talukdar, Toto-Moukouo, Tounian, Trask, van Popele, Wagenseil, Weisbrod, Wildman, Zhou   +66 more
core   +1 more source