Results 41 to 50 of about 9,068 (269)
International Journal of Molecular Medicine, 2019 The current study aimed to clarify the role of nucleolin in the phenotypic transformation of vascular smooth muscle cells (VSMCs) and to preliminarily explore its underlying mechanism.
Li Fang +5 more
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A coarse-grained mechanical model for folding and unfolding of tropoelastin with possible mutations
Acta Biomaterialia, 2021 Giuseppe Florio +3 more
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Circulation: Cardiovascular Imaging, 2018 Background: Elastolysis and ineffective elastogenesis favor the accumulation of tropoelastin, rather than cross-linked elastin, in atherosclerotic plaques. We developed gadolinium-labeled tropoelastin-specific magnetic resonance contrast agents for tropoelastin imaging in animal models. Methods
Phinikaridou, Alkystis +6 more
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Assessing the feasibility of CRISPRa approaches to enhance protein-based biomaterial expression in bacterial systems for more efficient production [PDF]
Materials Today BioRecombinant protein production is crucial for biomedical and industrial applications; however, achieving high yields for complex protein-like biomaterials such as elastin-like recombinamers (ELRs) remains challenging. ELRs, protein-based polymers derived
Pablo Rodríguez-Alonso +5 more
doaj +2 more sources
Biochemistry of tropoelastin [PDF]
European Journal of Biochemistry, 1998 Elastic fibres are an important component of the extracellular matrix and are made of two major components : the more abundant cross‐linked elastic protein elastin and the multi‐component microfibrils. The biosynthesis of elastic fibres is a complex process involving the interplay of many diverse proteins and genes with elastin as the major component ...
B, Vrhovski, A S, Weiss
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Fibrous Scaffolds From Elastin-Based Materials
Frontiers in Bioengineering and Biotechnology, 2021 Current cutting-edge strategies in biomaterials science are focused on mimicking the design of natural systems which, over millions of years, have evolved to exhibit extraordinary properties. Based on this premise, one of the most challenging tasks is to
Jose Carlos Rodriguez-Cabello +9 more
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Toll-like receptor 2 activation and serum amyloid A regulate smooth muscle cell extracellular matrix. [PDF]
PLoS ONE, 2017 Smooth muscle cells contribute to extracellular matrix remodeling during atherogenesis. De-differentiated, synthetic smooth muscle cells are involved in processes of migration, proliferation and changes in expression of extracellular matrix components ...
Stephanie E Seidl +6 more
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Frontiers in Materials, 2021 Porous biomaterials are of significant interest in a variety of biomedical applications as they enable the diffusion of nutrients and gases as well as the removal of metabolic waste from implants.
Lubinda Mbundi +5 more
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Radioimmunological identification of tropoelastin [PDF]
Biochemical Journal, 1976 Antiserum was prepared in sheep against insoluble elastin isolated from embryonic-chick aortae. In an indirect immunoprecipitation test, the antiserum reacted quantitatively with small amounts of radioactively labelled purified tropoelastin prepared from embryonic-chick aortae. The antiserum did not cross-react with chick procollagen, and the antiserum
P, Christner +3 more
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The FEBS Journal, 2021 Elastin is an extracellular matrix component with key structural and biological roles in elastic tissues. Interactions between resident cells and tropoelastin, the monomer of elastin, underpin elastin's regulation of cellular processes.
B. Bochicchio +8 more
semanticscholar +1 more source