Results 81 to 90 of about 7,724 (232)

Functional CRISPR‐Cas9 knockout screening of the genetic determinants of human fibroblast migration propensity

open access: yesBiotechnology Progress, EarlyView.
Abstract Directional cell migration plays a central role in a wide range of physiological and pathological conditions, such as embryonic development or tumor metastasis. Steps involved in cell migration include cell polarization, formation of membrane protrusions at the cell front side and adhesion disassembly at the rear side, and a general ...
Antonio Mazzei   +5 more
wiley   +1 more source

Alveolarization genes modulated by fetal tracheal occlusion in the rabbit model for congenital diaphragmatic hernia: a randomized study. [PDF]

open access: yesPLoS ONE, 2013
BACKGROUND: The mechanisms by which tracheal occlusion (TO) improves alveolarization in congenital diaphragmatic hernia (CDH) are incompletely understood.
Aline Vuckovic   +4 more
doaj   +1 more source

Magnetically responsive tropoelastin hydrogel as a platform for soft tissue regeneration applications [PDF]

open access: yes, 2017
Publicado em "European Cells and Materials. ISSN 1473-2262. Vol. 33, Suppl. 2, 2017 (0006)"The natural polymer tropoelastin is a structural protein of ECM of tissues requiring elasticity as part of their function, including ligaments and tendons ...
Almeida, Raquel Costa   +5 more
core  

Slc2a10 knock-out mice deficient in ascorbic acid synthesis recapitulate aspects of arterial tortuosity syndrome and display mitochondrial respiration defects

open access: yes, 2020
Arterial tortuosity syndrome (ATS) is a recessively inherited connective tissue disorder, mainly characterized by tortuosity and aneurysm formation of the major arteries.
Barnhoorn, Sander   +14 more
core   +1 more source

Biomolecular Changes Upon Ablative Laser Therapy of the Skin: A Scoping Review

open access: yesInternational Journal of Dermatology, EarlyView.
(Fractional) ablative laser therapy results in a wound healing response characterized by an inflammatory phase, dermal matrix degradation, and remodeling, collagenesis and elastogenesis. This is characterized by an increase in metalloproteinases, collagen type I, III, VII, and tropoelastin.
Marie‐Eline Pauline Henriette Debeuf   +4 more
wiley   +1 more source

PKCε Increases Extracellular Elastin and Fibulin-5/DANCE in Dermal Fibroblasts

open access: yesCellular Physiology and Biochemistry, 2018
Background/Aims: In the earlier study, the selective PKCε activator DCP-LA increased elastic fibres in the dermis of HR-1 hairless mice. As a process of elastic fibre formation, tropoelastin, an elastin monomer, is secreted into the extracellular space ...
Tomoyuki Nishizaki
doaj   +1 more source

A comparative study of the elastic fibre system within the mouse and human cornea [PDF]

open access: yes, 2018
The cornea relies on its organised extracellular matrix for maintaining transparency and biomechanical strength. Studies have identified an elastic fibre system within the human posterior cornea, thought to allow for slight deformations in response to ...
Feneck, Eleanor M.   +3 more
core   +2 more sources

Bioinspired Design of a Wet‐Adhesive Cornea Glue Based on Recombinant Human Protein Networks

open access: yesAdvanced Functional Materials, Volume 36, Issue 4, 12 January 2026.
Natures protein‐based high performance materials e.g. elastin, silk and muscle proteins have been mimicked by a new protein‐hybrid material based on redesigned human partial sequences only, showing high wet‐adhesiveness and elasticity for biomedical applications.
Anna Resch   +17 more
wiley   +1 more source

Elastin in the Liver

open access: yesFrontiers in Physiology, 2016
A characteristic feature of liver cirrhosis is the accumulation of large amounts of connective tissue with the prevailing content of type I collagen. Elastin is a minor connective tissue component in normal liver but it is actively synthesized by hepatic
Jiri Kanta
doaj   +1 more source

Roles of fibronectin isoforms in neonatal vascular development and matrix integrity [PDF]

open access: yes, 2018
Fibronectin (FN) exists in two forms—plasma FN (pFN) and cellular FN (cFN). Although the role of FN in embryonic blood vessel development is well established, its function and the contribution of individual isoforms in early postnatal vascular ...
Brinckmann, Jurgen   +6 more
core   +2 more sources

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