Results 81 to 90 of about 6,608 (237)

Elastin in the Liver

Frontiers in Physiology, 2016
A characteristic feature of liver cirrhosis is the accumulation of large amounts of connective tissue with the prevailing content of type I collagen. Elastin is a minor connective tissue component in normal liver but it is actively synthesized by hepatic
Jiri Kanta
doaj   +1 more source

Bio‐inspired functional coacervates

Aggregate, 2022
Many functional coacervates have been identified in biological systems, which have attracted widespread interest. Coacervation is a liquid–liquid phase separation (LLPS) process in which a macromolecule‐enriched liquid phase is formed together with a ...
Shujun Chen, Qi Guo, Jing Yu
doaj   +1 more source

Arterial stiffening in western diet-fed mice is associated with increased vascular elastin, transforming growth factor-ß, and plasma neuraminidase [PDF]

, 2016
Consumption of excess fat and carbohydrate (Western diet, WD) is associated with alterations in the structural characteristics of blood vessels. This vascular remodeling contributes to the development of cardiovascular disease, particularly as it affects
Alvira, Aneja, Arribas, Baydanoff, Bender, Billaud, Bizbiz, Blaise, Boak, Briones, Carlson, Castorena-Gonzalez, Clifford, Dantas, Davis, de Onis, DeMarco, Duprez, Emoto, George, Guilherme, Heinemann, Hinek, Hinek, Horiguchi, Huxley, Jia, Jung, Katz, Kielty, Kielty, Kuang, Kucich, Kucich, Kwon, Ledoux, Lesniewski, Majane, Martinez-Lemus, Matthews, McGill, McGowan, Mulvany, Nicoloff, Nistala, Parikh, Payne, Pennington, Roozbeh, Sandow, Sehgel, Shen, Souza-Smith, Sproul, Stehouwer, Stolarczyk, Straub, Sutton-Tyrrell, Talukdar, Toto-Moukouo, Tounian, Trask, van Popele, Wagenseil, Weisbrod, Wildman, Zhou   +66 more
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Tropoelastin: A versatile, bioactive assembly module [PDF]

Acta Biomaterialia, 2014
Elastin provides structural integrity, biological cues and persistent elasticity to a range of important tissues, including the vasculature and lungs. Its critical importance to normal physiology makes it a desirable component of biomaterials that seek to repair or replace these tissues.
Anthony S. Weiss, Steven G. Wise, David L. Kaplan, Jelena Rnjak-Kovacina, Martin K.C. Ng, Giselle C. Yeo, Matti A. Hiob   +6 more
openaire   +3 more sources

Functional Biomaterials Derived from Protein Liquid–Liquid Phase Separation and Liquid‐to‐Solid Transition

Advanced Materials, Volume 37, Issue 22, June 5, 2025.
Protein can undergo liquid–liquid phase separation and liquid‐to‐solid transition to form liquid condensates and solid aggregates. These phase transitions can be influenced by post‐translational modifications, mutations, and various environmental factors.
Tianchen Li, Dea Ilhamsyah, Benedict Tai, Yi Shen   +3 more
wiley   +1 more source

Allysine modifications perturb tropoelastin structure and mobility on a local and global scale

Matrix Biology Plus, 2019
Elastin provides elastic tissues with resilience through stretch and recoil cycles, and is primarily made of its extensively cross-linked monomer, tropoelastin.
Jazmin Ozsvar, Anna Tarakanova, Richard Wang, Markus J. Buehler, Anthony S. Weiss   +4 more
doaj  

Mechanistic Insight into the Elastin Degradation Process by the Metalloprotease Myroilysin from the Deep-Sea Bacterium Myroides profundi D25

Marine Drugs, 2015
Elastases have been widely studied because of their important uses as medicine and meat tenderizers. However, there are relatively few studies on marine elastases. Myroilysin, secreted by Myroides profundi D25 from deep-sea sediment, is a novel elastase.
Jie Yang, Hui-Lin Zhao, Bai-Lu Tang, Xiu-Lan Chen, Hai-Nan Su, Xi-Ying Zhang, Xiao-Yan Song, Bai-Cheng Zhou, Bin-Bin Xie, Anthony S. Weiss, Yu-Zhong Zhang   +10 more
doaj   +1 more source

Polymorphisms in the human tropoelastin gene modify in vitro self-assembly and mechanical properties of elastin-like polypeptides. [PDF]

PLoS ONE, 2012
Elastin is a major structural component of elastic fibres that provide properties of stretch and recoil to tissues such as arteries, lung and skin. Remarkably, after initial deposition of elastin there is normally no subsequent turnover of this protein ...
David He, Ming Miao, Eva E Sitarz, Lisa D Muiznieks, Sean Reichheld, Richard J Stahl, Fred W Keeley, John Parkinson   +7 more
doaj   +1 more source

Wound dressings for a proteolytic-rich environment [PDF]

, 2011
Wound dressings have experienced continuous and significant changes over the years based on the knowledge of the biochemical events associated with chronic wounds.
A Hinek, A Hinek, A Hinek, A Schneider, A Tachibana, A Vasconcelos, AF Falabella, AF Morey, AJ Kuijpers, AM Breen, Andreia Vasconcelos, AP Negri, AR Fitton, AR Halbert, Artur Cavaco-Paulo, AY Mensah, B Balakrishnan, B Balakrishnan, B Balakrishnan, B Cullen, B Hafemann, B Panilaitis, BAC Harley, BB Mandal, BB Mandal, BC Griffith, BM Kuehn, C Buchta, C Earland, C Martyn, C Wong Po Foo, C Yang, C Yang, C-M Deng, C-M Ding, C-Z Zhou, CH Lee, CH Yao, CJ Doillon, CJ Doillon, CM Bellingham, CZ Zhou, D Berry, D Gopinath, D Huemmerich, D Le Nihouannen, D Michel, D Queen, DAD Parry, DC Daltrey, DJ Smith, DJ Vachon, DL Kaplan, DL Kaplan, DR Eyre, DR Goddard, DW Urry, E Rossitch, E Wright, EA Yücel, EN Lamme, EN Lamme, F Auger, F Breinl, F Strodtbeck, F Vollrath, FJ O’Brien, G Chen, G Chen, G Faury, G Man, G Wechselberger, GH Altman, GS Lazarus, H Bannasch, H De Vries, H Schmoekel, H-J Jin, HJ Jin, HM Powell, HM Powell, I Grant, I Ono, I Ono, I Pasquali-Ronchetti, IC Um, III Bidwell, IJ O’Donnell, J Lee, J Lee, J Oju, J Reguera, J Rosenbloom, J-P Chen, J-T Schantz, JA Maclaren, JE Plowman, JH Buchanan, JL Long, JN Kearney, JP Nicholas, JS Boateng, K Hori, K Inngjerdingen, K Kawai, K Kawai, K Madsen, K Ulubayram, KF Cutting, KG Harding, KS Rho, L Duca, LF Drummy, LR Moy, M Ehrbar, M Feughelmann, M Yamamoto, MB Dainiak, MJ Humphries, MJ McClure, MP Curran, MP Jacob, MR Neidert, MS Kumar, MW Dunn, N Adhirajan, NT Dai, PG Bowler, PG Bowler, PG Bowler, PH Jørgensen, PPM van Zuijlen, Q Lu, R Herrero-Vanrell, R Okabayashi, R Ross, R Sanjay, RE Unger, RL Horan, RL Reis, RMZ Farahani, RP Mecham, S Ayad, S Hamasaki, S Hofmann, S Huang, S Inoue, S Thilagar, S Thomas, S Winkler, S-J Liu, S-Y Gu, SA Wood, SC Sehgal, SE Gardner, SK Purna, SM Baughman, SM Mithieux, SM Partridge, SM Willerth, SP Zhong, T Aper, T Hashimoto, T Hino, T Kitajima, T-W Wang, U Schönfelder, UR Shettigar, V Verma, W Haslik, W Haslik, W Jiang, W Thomas, W Wang, WF Daamen, WG Crewther, WS Douglas, WYJ Chen, X Wang, Y Garcia, Y Ikada, Y Wang, Y-Q Zhang, YH Chen, YH Chen, Z Ruszczak, Z Wu   +186 more
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Imaging of Dysfunctional Elastogenesis in Atherosclerosis Using an Improved Gadolinium-Based Tetrameric MRI Probe Targeted to Tropoelastin [PDF]

, 2021
Dysfunctional elastin turnover plays a major role in the progression of atherosclerotic plaques. Failure of tropoelastin cross-linking into mature elastin leads to the accumulation of tropoelastin within the growing plaque, increasing its instability ...
Aime S., Almouazen E., Botnar R. M., Capuana F., Chevalier Y., Digilio G., Heinrich-Balard L., Lacerda S., Lavin B., Padovan S., Phinikaridou A., Stefania R.   +11 more
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