Results 161 to 170 of about 76,365 (337)

Highly Homologous Filamin Polypeptides Have Different Distributions in Avian Slow and Fast Muscle Fibers [PDF]

, 1983
The high molecular weight actin-binding protein filamin is located at the periphery of the Z disk in the fast adult chicken pectoral muscle (Gomer, R. H., and E. Lazarides, 1981, Cell, 23: 524-532).
Gomer, Richard H., Lazarides, Elias
core   +1 more source

ProteinDJ: A high‐performance and modular protein design pipeline

Protein Science, Volume 35, Issue 2, February 2026.
Abstract Leveraging artificial intelligence and deep learning to generate proteins de novo (a.k.a. ‘synthetic proteins’) has unlocked new frontiers of protein design. Deep learning models trained on protein structures can generate novel protein designs that explore structural landscapes unseen by evolution.
Dylan Silke, Julie Iskander, Junqi Pan, Andrew P. Thompson, Anthony T. Papenfuss, Isabelle S. Lucet, Joshua M. Hardy   +6 more
wiley   +1 more source

Role of Tpm Isoforms Produced by the TPM4 Gene in the Regulation of Actin Filament Dynamics by Cofilin

Biomolecules
The actin cytoskeleton determines a huge number of intracellular processes, as well as maintaining the cell shape, transport, formation of intercellular contacts, etc.
Svetlana G. Roman, Victoria V. Nefedova, Alexander M. Matyushenko   +2 more
doaj   +1 more source

Integrated Multi‐Omic Analysis Identifies Altered Colonic Brush Border Profile as a Key Feature of Microscopic Colitis

United European Gastroenterology Journal, Volume 14, Issue 1, February 2026.
ABSTRACT Background Microscopic colitis (MC), comprising lymphocytic colitis (LC) and collagenous colitis (CC), is an inflammatory bowel disease with increasing incidence. MC etiopathogenesis remains unknown; however, altered colonic epithelial integrity may underlie uncontrolled luminal antigen passage, triggering immuno‐inflammatory responses ...
Danila Guagnozzi, Ana Maria Gonzalez‐Castro, Yamile Zabana, Fernando Fernández‐Bañares, Andreas Münch, Eva Tristan, Juan‐José Lozano, Julia Sidorova, Beatriz Lobo, Carmen Alonso‐Cotoner, Elba Exposito, Alfredo J. Lucendo, Stefania Landolfi, Ana Benages, Ronald Llerena‐Castro, Maria Dolores Castillo Cejas, Joan Dot, Javier Santos, Maria Vicario   +18 more
wiley   +1 more source

The 68,000-Dalton Neurofilament-Associated Polypeptide is a Component of Nonneuronal Cells and of Skeletal Myofibrils [PDF]

, 1980
Purified preparations of 10-nm neurofilaments from rat spinal cord and bovine or porcine brain contain a predominant 68,000-dalton polypeptide. This polypeptide is also a major component of the neurofilaments that copurify with brain tubulin isolated by ...
Asai, David J., Lazarides, Elias, Wang, Chung   +2 more
core  

Shellfish allergens: tropomyosin and beyond

Allergy. European Journal of Allergy and Clinical Immunology, 2017
M. Faber, Mariona Pascal, O. E. Kharbouchi, V. Sabato, M. Hagendorens, I. Decuyper, C. Bridts, D. G. Ebo   +7 more
semanticscholar   +1 more source

A Novel Brain Penetrable Nanocarrier Delivers Brain‐Derived Neurotrophic Factor to Treat Alzheimer's Disease

Advanced Healthcare Materials, Volume 15, Issue 1, 9 January 2026.
A novel blood‐brain barrier‐penetrating terpolymer nanoparticle to deliver brain‐derived neurotrophic factor (BDNF) for the treatment of Alzheimer's disease (AD) is designed. The BDNF‐TPN significantly enhances BDNF accumulation in the brain following intravenous injection, reduces apoptosis and neuroinflammation, thus promoting neuronal survival and ...
Lily Yi Li, Elliya Park, Chunsheng He, Azhar Z. Abbasi, Pei Zhi, Paul E. Fraser, Andrew M. Rauth, Jeffery T. Henderson, Xiao Yu Wu   +8 more
wiley   +1 more source

Splicing of two alternative exon pairs in beta-tropomyosin pre-mRNA is independently controlled during myogenesis.

, 1992
Yuanchao Wang, Peter A. Rubenstein
openalex   +1 more source

Steap4 Promotes Senile Osteoporosis via Fe2+‐ROS/C/EBPβ Feedback‐Driven Ferroptosis and Adipogenesis in Senescent BMSCs

Advanced Science, Volume 13, Issue 5, 27 January 2026.
Senescent bone marrow mesenchymal stem cells (BMSCs) exhibit increased sensitivity to ferroptosis, a phenomenon associated with Steap4, a nicotinamide adenine dinucleotide phosphate hydrogen (NADPH)‐dependent metalloreductase that reduces Fe3+ to Fe2+.
Liangliang Wang, Guangrong Yin, Wenming Li, Maoyuan Li, Feng Lu, Chao Xu, Gongyin Zhao, Dechun Geng, Jiaxiang Bai, Yuji Wang   +9 more
wiley   +1 more source

Temperature-Dependence of Isometric Tension and Cross-Bridge Kinetics of Cardiac Muscle Fibers Reconstituted with a Tropomyosin Internal Deletion Mutant [PDF]

, 2006
Xiaoying Lü, Larry S. Tobacman, Masataka Kawai   +2 more
openalex   +1 more source