Results 71 to 80 of about 27,067 (198)

Sarcomeric Gene Variants and Their Role with Left Ventricular Dysfunction in Background of Coronary Artery Disease

open access: yesBiomolecules, 2020
Cardiovascular diseases are one of the leading causes of death in developing countries, generally originating as coronary artery disease (CAD) or hypertension. In later stages, many CAD patients develop left ventricle dysfunction (LVD).
Surendra Kumar   +2 more
doaj   +1 more source

Identification of human metabolites of fast skeletal troponin activators Tirasemtiv and Reldesemtiv for doping control purposes

open access: yesDrug Testing and Analysis, EarlyView.
The metabolism and urinary elimination of two substances recently classified as prohibited substances in sport was conducted, yielding suitable target analytes for efficient doping controls employing routinely applied chromatographic‐mass spectrometric test methods.
Luisa Euler   +4 more
wiley   +1 more source

Dilated cardiomyopathy evaluation with Imagenomics: combining multimodal cardiovascular imaging and genetics

open access: yesESC Heart Failure, EarlyView.
Systematic approach to dilated cardiomyopathy diagnosis. Dilated cardiomyopathy is a clinical diagnosis characterized by the presence of left ventricular dilatation and systolic disfunction unexplained by abnormal loading conditions or coronary artery disease.
Kristian Galanti   +14 more
wiley   +1 more source

Single-molecule study on the orientation of coiled-coil proteins attached to gold nanostructures [PDF]

open access: yesarXiv, 2015
Methods for patterning biomolecules on a substrate at the single molecule level have been studied as a route to sensors with single-molecular sensitivity or as a way to probe biological phenomena at the single-molecule level. However, the arrangement and orientation of single biomolecules on substrates has been less investigated.
arxiv  

Interaction of plasma gelsolin with tropomyosin [PDF]

open access: yesFEBS Letters, 1992
Horse plasma gelsolin labelled with benzophenone‐4‐isothiocyanate can be photochemically cross‐linked to rabbit cardiac tropomyosin. The cross‐linking proceeds with greater efficiency in calcium‐containing buffers. Further evidence for interaction between these proteins is provided by retention of fluorescently labelled gelsolin on tropomyosin‐agarose ...
Leslie D. Burtnick, Edward K. Koepf
openaire   +3 more sources

Butyrate alleviates food allergy by improving intestinal barrier integrity through suppressing oxidative stress‐mediated Notch signaling

open access: yesiMeta, EarlyView.
Compared to healthy controls, children with food‐sensitized tolerance and food allergy showed reduced fecal short‐chain fatty acids (SCFAs), particularly butyrate. In an ovalbumin‐sensitized mouse model, butyrate outperformed other SCFAs in alleviating allergic responses.
Jialu Shi   +11 more
wiley   +1 more source

Transglutaminase-catalysed cross-linking eliminates Penaeus chinensis tropomyosin allergenicity by altering protein structure

open access: yesFood and Agricultural Immunology, 2019
Transglutaminase (TG) is a major food processing enzyme that induces protein cross-linking. Tropomyosin (TM) is a major shellfish allergen that is responsible for at least 80% of the shrimp allergic incidents.
Linglin Fu   +3 more
doaj   +1 more source

The native subunit pattern of tropomyosin [PDF]

open access: yesFEBS Letters, 1976
Tropomyosin is a rod-shaped protein with a molecular weight of 66 000-68 000 and is composed of two parallel, a-helical polypeptide chains [l-3]. It aggregates in vivo in head-to-tail fashion and lies in the grooves of the double-stranded F-actin filaments [4].
Gale M. Strasburg, Marion L. Greaser
openaire   +3 more sources

Harnessing the therapeutic potential of bacterial extracellular vesicles via functional peptides

open access: yesInterdisciplinary Medicine, EarlyView.
Bacterial extracellular vesicles (BEVs) are increasingly exploited as therapeutic agents or delivery vehicles for disease treatment due to their intrinsic structure, delivery capacity, immunogenic property, facile production, and versatile modification.
Yejiao Shi   +3 more
wiley   +1 more source

Changing of expression actinbinding proteins in the kidney under dehydration

open access: yesВавиловский журнал генетики и селекции, 2018
Actin is related to main structural proteins in eukaryotes. In opposite to muscle alpha-actin, beta-actin is expressing in all types of cells. The constant reorganization of actin cytoskeleton takes place in non-muscle cells.
I. I. Khegay
doaj   +1 more source

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