Cellular mechanisms in sympatho‐modulation of the heart [PDF]
Cardiovascular function relies on complex servo-controlled regulation mechanisms that involve both fast-acting feedback responses and long-lasting adaptations affecting the gene expression.
Schaub, M. C., Zaugg, M.
core
Global proteomics analysis of the response to starvation in C. elegans [PDF]
Periodic starvation of animals induces large shifts in metabolism but may also influence many other cellular systems and can lead to adaption to prolonged starvation conditions.
Alejandro Brenes Murillo+52 more
core +2 more sources
Brain-derived neurotrophic factor (BDNF) is a neurotrophin that has pleiotropic effects on neuronal morphology and synaptic plasticity that underlie hippocampal circuit development and cognition.
Ana Paula De Vincenti+5 more
doaj +1 more source
The interplay between microRNAs and the neurotrophin receptor tropomyosin-related kinase C controls proliferation of human neuroblastoma cells [PDF]
Pietro Laneve+7 more
openalex +1 more source
[18F]TRACK, a PET tracer for imaging of tropomyosin receptor kinases (Trk): Efficient radiosynthesis and preliminary evaluation in the TgF344‐AD rat model of Alzheimer’s disease [PDF]
Min Su Kang+11 more
openalex +1 more source
Role of Glutamate Excitotoxicity in Glioblastoma Growth and Its Implications in Treatment
ABSTRACT Glioblastoma is a highly malignant and invasive type of primary brain tumor that originates from astrocytes. Glutamate, a neurotransmitter in the brain plays a crucial role in excitotoxic cell death. Excessive glutamate triggers a pathological process known as glutamate excitotoxicity, leading to neuronal damage.
Colin Moriarty+2 more
wiley +1 more source
Diet transition to a high-fat diet for 3 weeks reduces brain omega-3-fatty acid levels, alters BDNF signaling and induces anxiety & depression-like behavior in adult rats [PDF]
Background: The consumption of diets high in calories and low in nutrient value is becoming increasingly common in modern society, which can lead to metabolic disorders like diabetes and obesity, and potentially to psychiatric disorders.
Fernando Gomez-Pinilla+2 more
core +1 more source
Yizhi Qingxin Formula Extract Ameliorates Cognitive Decline in Aged Rats via the Brain-Derived Neurotrophic Factor/Tropomyosin Receptor Kinase B Pathway [PDF]
Lina Ma+7 more
openalex +1 more source
Lattice ultrasensitivity amplifies signals in E. coli without fine-tuning [PDF]
The E. coli chemosensory lattice, consisting of receptors, kinases, and adaptor proteins, is an important test case for biochemical signal processing. Kinase output is characterized by precise adaptation to a wide range of background ligand levels and large gain in response to small relative changes in concentration.
arxiv
ABSTRACT Background Infantile fibrosarcoma (IFS) is a rare pediatric tumor of intermediate malignancy with high local aggressiveness that typically presents in young infants. Its occurrence in the head and neck region is rare. Complete non‐mutilating surgical resection is often not possible, requiring multimodal treatment.
Teresa M. Cardesa‐Salzmann+14 more
wiley +1 more source