Results 101 to 110 of about 107,195 (244)

Early Origins of Asthma and Allergies: Clues From Studies in China

Clinical &Experimental Allergy, EarlyView.
The environment we live in harbours both risk and protective factors for asthma and allergies. This is particularly relevant in China, where unique environmental and cultural factors shape disease development. The interplay between these environmental factors, airway immunity, and gut microbiome shapes the susceptibility to asthma and allergies ...
Yike Wang, Jing Yang, Xueling Lai, Agnes Sze‐Yin Leung, Yuhan Xing, Gary Wing‐Kin Wong   +5 more
wiley   +1 more source

Global proteomics analysis of the response to starvation in C. elegans [PDF]

, 2015
Periodic starvation of animals induces large shifts in metabolism but may also influence many other cellular systems and can lead to adaption to prolonged starvation conditions.
Alejandro Brenes Murillo, Angelo, Angus I. Lamond, Anton Gartner, Baugh, Bin Wang, Chang, Cox, Cui, Dong, Ehsan Pourkarimi, Felix, Fredens, Grun, Handke, Henderson, Hsin, Huang, Kaeberlein, Kenyon, Larance, Larance, Larance, Liang, Long, Ly, Mark Larance, McBryant, Murphy, Narbonne, Ong, Ooi, Pourkarimi, Raharjo, Rechavi, Ritorto, Robert Kent, Sabidó, Seidel, Sheaffer, Shen, Supek, Uno, Updike, Van Gilst, Van Gilst, Vellai, Wessel, Whittle, Yankovskaya, You, Yuan, Zhao   +52 more
core   +2 more sources

Membrane Receptor-Induced Changes of the Protein Kinases A and C Activity May Play a Leading Role in Promoting Developmental Synapse Elimination at the Neuromuscular Junction

Frontiers in Molecular Neuroscience, 2017
Synapses that are overproduced during histogenesis in the nervous system are eventually lost and connectivity is refined. Membrane receptor signaling leads to activity-dependent mutual influence and competition between axons directly or with the ...
Josep M. Tomàs, Neus Garcia, Maria A. Lanuza, Laura Nadal, Marta Tomàs, Erica Hurtado, Anna Simó, Víctor Cilleros   +7 more
doaj   +1 more source

Membrane trafficking of synaptic adhesion molecules

The Journal of Physiology, EarlyView.
Abstract figure legend Synaptic cellular adhesion molecules are surface transmembrane receptors that have been shown to internalize via endocytosis, and possibly also recycle, in a process that has been linked to the function and the turnover of the synaptic contact site.
Cristian A. Bogaciu, Silvio O. Rizzoli
wiley   +1 more source

Blocking the tropomyosin receptor kinase A (TrkA) receptor inhibits pain behaviour in two rat models of osteoarthritis [PDF]

, 2015
Objectives: Tropomyosin receptor kinase A (TrkA) mediates nociceptor sensitisation by nerve growth factor (NGF), but it is unknown whether selective TrkA inhibition will be an effective strategy for treating osteoarthritis (OA) pain.
Apfel, Ashraf, Ayral, Barouch, Barthel, Bove, Bullock, Burston, Christiansen, David A Walsh, Felson, Fischer, Gerwin, Ghilardi, Ghilardi, Guingamp, Hill, Hochberg, Ivanavicius, Iwakura, Kidd, Lane, Laslett, Lilian N Nwosu, Linker, Lu, Ma, Manni, Mapp, Mapp, Mapp, McMahon, McNamee, Nicol, Nilsson, Opar, Orita, Paul I Mapp, Sagar, Sagar, Sagar, Sanga, Schaible, Schnitzer, Suokas, Szebenyi, Tiseo, Torres, Unger, Victoria Chapman, Walsh, Watson, Štempelj   +52 more
core   +1 more source

Brain-derived neurotrophic factor/tropomyosin-related kinase B pathway in gastric cancer

British Journal of Cancer, 2012
Background:Brain-derived neutrophic factor (BDNF) is a member of the neutrophin family that is known to activate the high-affinity tropomyosin-related receptor kinase B (TrkB).
Y. Okugawa, Koji Tanaka, Y. Inoue, M. Kawamura, A. Kawamoto, Jyunichiro Hiro, S. Saigusa, Y. Toiyama, M. Ohi, K. Uchida, Y. Mohri, M. Kusunoki   +11 more
semanticscholar   +1 more source

The central benefit of physiologically induced ketogenic states

The Journal of Physiology, EarlyView.
Abstract figure legend This review describes the association between ketogenic states induced by physiological interventions such as fasting or aerobic exercise, exogenous ketone supply and ketogenic diets, as well as increased cognition through increased activity of brain‐derived neurotrophic factor (BDNF).
Antonia Giacco, Giuseppe Petito, Rosalba Senese, Maria Moreno, Assunta Lombardi, Antonia Lanni, Pieter de Lange   +6 more
wiley   +1 more source

Cellular mechanisms in sympatho‐modulation of the heart [PDF]

, 2017
Cardiovascular function relies on complex servo-controlled regulation mechanisms that involve both fast-acting feedback responses and long-lasting adaptations affecting the gene expression.
Schaub, M. C., Zaugg, M.
core  

Neurotrophins are expressed in giant cell arteritis lesions and may contribute to vascular remodeling [PDF]

, 2014
International audienceIntroduction: Giant cell arteritis (GCA) is characterized by intimal hyperplasia leading to ischaemic manifestations that involve large vessels.
Alexis Régent, Anne-Laure Fauchais, Antoine Brézin, Claire Le-Jeunne, Elisabeth Vidal, Elsa Molina, François Labrousse, Jean-Louis Bourges, Kim Heang Ly, Luc Mouthon, Marie-Odile Jauberteau, Philippe Bertin, Philippe Sindou, Pierre-Yves Robert, Sofiane Saada, Véronique Witko-Sarsat   +15 more
core   +2 more sources

Pro-nerve Growth Factor Induces Autocrine Stimulation of Breast Cancer Cell Invasion through Tropomyosin-related Kinase A (TrkA) and Sortilin Protein*

Journal of Biological Chemistry, 2011
The precursor of nerve growth factor (proNGF) has been described as a biologically active polypeptide able to induce apoptosis in neuronal cells, via the neurotrophin receptor p75NTR and the sortilin receptor.
Y. Demont, C. Corbet, Adeline Page, Y. Ataman-Önal, G. Choquet-Kastylevsky, Ingrid Fliniaux, X. Le Bourhis, R. Toillon, R. Bradshaw, H. Hondermarck   +9 more
semanticscholar   +1 more source