Results 51 to 60 of about 107,195 (244)
Current Research in Physiology, 2021 Zinc finger protein 1 (ZPR1) is required for cellular replication and viability. Recently, ZPR1 variant rs964184 has been repeatedly linked to high plasma triglyceride levels, metabolic syndrome, type 2 diabetes mellitus (T2DM), and nonalcoholic fatty ...
Mythri Chittilla +2 more
doaj
Life, 2021 Ovarian cancer is the most lethal gynecological neoplasm, and epithelial ovarian cancer (EOC) accounts for 90% of ovarian malignancies. The 5-year survival is less than 45%, and, unlike other types of cancer, the proportion of women who die from this ...
Daniela B. Vera +3 more
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BAC-FISH assays delineate complex chromosomal rearrangements in a case of post-Chernobyl childhood thyroid cancer [PDF]
, 2009 Structural chromosome aberrations are known hallmarks of many solid tumors. In the papillary form of thyroid cancer (PTC), for example, activation of the receptor tyrosine kinase (RTK) genes, RET and neurotrophic tyrosine kinase receptor type I (NTRK1)
Baumgartner, Adolf +6 more
core +2 more sources
Annals of the Rheumatic Diseases, 2023 Osteoarthritis (OA) is a disease of the entire joint. OA causes significant pain that has been linked to increased neurotrophin concentrations, including mature nerve growth factor β-NGF[2].
A. Altaie +7 more
semanticscholar +1 more source
Genetically Encoded Biosensors Reveal PKA Hyperphosphorylation on the Myofilaments in Rabbit Heart Failure [PDF]
, 2016 RATIONALE: In heart failure, myofilament proteins display abnormal phosphorylation, which contributes to contractile dysfunction. The mechanisms underlying the dysregulation of protein phosphorylation on myofilaments is not clear.
Barbagallo, Federica +15 more
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Role of the nervous system in cancer metastasis [PDF]
, 2018 Cancer remains as one of the leading cause of death worldwide. The development of cancer involves an intricate process, wherein many identified and unidentified factors play a role.
Apostolopoulos, Vasso +3 more
core +3 more sources
TrkB-enhancer facilitates functional recovery after traumatic brain injury
Scientific Reports, 2017 Brain-derived neurotrophic factor (BDNF), a key player in regulating synaptic strength and learning, is dysregulated following traumatic brain injury (TBI), suggesting that stimulation of BDNF signaling pathways may facilitate functional recovery.
John Marshall +9 more
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BMC Genomics, 2011 Background Nerve growth factor (NGF) is a potent growth factor that plays a key role in neuronal cell differentiation and may also play a role in hematopoietic differentiation.
Dittrich-Breiholz Oliver +6 more
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Functional Classification of Skeletal Muscle Networks. I. Normal Physiology [PDF]
, 2012 Extensive measurements of the parts list of human skeletal muscle through transcriptomics and other phenotypic assays offer the opportunity to reconstruct detailed functional models.
Subramaniam, Shankar +2 more
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Precision medicine becomes reality—tumor type-agnostic therapy
Cancer Communications, 2018 Precision medicine just witnessed two breakthroughs in oncology in 2017. Pembrolizumab (Keytruda), Merck’s anti-programmed cell death-1 (PD-1) monoclonal antibody (mAb), received accelerated approval in May 2017 by the US Food and Drug Administration for
Li Yan, Wei Zhang
doaj +1 more source