Results 111 to 120 of about 238,995 (362)

Impact of Rapid Exome Sequencing on Pediatric Patients With Cardiomyopathy and Acute Heart Failure

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Few studies describe the impact of rapid exome sequencing (ES) on pediatric cardiomyopathy in urgent clinical settings. Here, we retrospectively report the impact of rapid singleton ES in pediatric patients presented with acute heart failure and isolated cardiomyopathy or myocarditis, between 2021 and 2023 at a single tertiary care center.
Tameemi Abdalla Moady, Tova Hershkovitz, Clair Habib, Ori Attias, Amir Hadash, Galit Tal, Asaad Khoury, Josef Ben‐Ari, Danny Eytan, Tamar Paperna, Karin Weiss   +10 more
wiley   +1 more source

Dynamics of semiflexible polymer solutions in the tightly entangled concentration regime [PDF]

, 2017
I corroborate an important experimental evidence reported by Schuldt et al. [ Phys. Rev. Lett. 2016, 117, 197801] revealing the incapability of the current theoretical framework to fully describe the dynamics of semiflexible polymer solutions in the ...
Tassieri, Manlio
core   +1 more source

Generating golden Syrian hamsters with conditional alleles via zygote microinjection of CRISPR/Cas9

Animal Models and Experimental Medicine, EarlyView.
We established the first conditional knockout (cKO) model in the golden Syrian hamster by CRISPR/Cas9‐mediated genome editing. Cas9 protein, two sgRNAs, and a donor plasmid carrying loxP‐flanked exon 2 of the ApoF gene were microinjected into one‐cell embryos. The floxed allele was efficiently generated (up to 27%) and transmitted through the germline.
Wei Chen, Xu Zhang, Rui Fan, Xia Li, Feifei Guan, Gefan Wan, Weining Kong, Xiaolong Qi, Shuo Pan, Sijing Shi, Yuanlong Su, Shan Gao, Wei Huang, Xunde Xian, Jiangning Liu, Yuhui Wang, Yuanwu Ma   +16 more
wiley   +1 more source

Providing Rapid Out of Hospital Acute Cardiovascular Treatment 4 (PROACT‐4)

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2015
Background Whether prehospital point‐of‐care (POC) troponin further accelerates the time to diagnosis in patients with chest pain (CP) is unknown. We conducted a randomized trial of POC‐Troponin testing in the ambulance. Methods and Results Patients with
Justin A. Ezekowitz, Robert C. Welsh, Dale Weiss, Michael Chan, William Keeble, Fadi Khadour, Sanjay Sharma, Wayne Tymchak, Sunil Sookram, Neil Brass, Darren Knapp, Thomas L. Koshy, Yinggan Zheng, Paul W. Armstrong   +13 more
doaj   +1 more source

High‐Sensitivity Troponin I Levels and Coronary Artery Disease Severity, Progression, and Long‐Term Outcomes

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2018
BackgroundThe associations between high‐sensitivity troponin I (hsTnI) levels and coronary artery disease (CAD) severity and progression remain unclear.
Ayman Samman Tahhan, Pratik Sandesara, Salim S. Hayek, Muhammad Hammadah, Ayman Alkhoder, Heval M. Kelli, Matthew Topel, Wesley T. O'Neal, Nima Ghasemzadeh, Yi‐An Ko, Mohamad Mazen Gafeer, Naser Abdelhadi, Fahad Choudhary, Keyur Patel, Agim Beshiri, Gillian Murtagh, Jonathan Kim, Peter Wilson, Leslee Shaw, Viola Vaccarino, Stephen E. Epstein, Laurence Sperling, Arshed A. Quyyumi   +22 more
doaj   +1 more source

INITIAL TROPONIN LEVEL AND ECHOCARDIOGRAPHIC FINDINGS IN SEVERE COVID-19

, 2021
Sant Kumar, Nayrana Griffith, Kathleen Abalos, Virginia Malatack, Monvadi Srichai-Parsia, Alex Montero   +5 more
openalex   +2 more sources

The implementation of persuasive technology principles in mobile application development: a qualitative study [PDF]

, 2017
Preceding studies of persuasive technology have mentioned several benefits on the implementation of persuasive design features of the Persuasive System Design (PSD) model such as creating users' engagement and acceptance and continuous usage.
Shafin, Noor Afifah
core  

Skeletal Muscle Biomarkers of Amyotrophic Lateral Sclerosis: A Large‐Scale, Multi‐Cohort Proteomic Study

Annals of Neurology, EarlyView.
Objective Biomarkers with clear contexts of use are important tools for amyotrophic lateral sclerosis (ALS) therapy development. Understanding their longitudinal trajectory in the untreated state is key to their use as potential markers of pharmacodynamic response.
Oleksandr Dergai, Joanne Wuu, Magdalena Koziczak‐Holbro, Andrea Malaspina, Volkan Granit, Jessica P. Hernandez, Anne Cooley, Ruchika Sachdev, Lili Yu, Michael Bidinosti, Ludivine Flotte, Mark Nash, Lori L. Jennings, James D. Berry, Lucie I. Bruijn, Sophie Brachat, Michael Benatar   +16 more
wiley   +1 more source

HEAR SCORE: A Proposal to Use Only Anamnestic and EKG Data to Evaluate Patients with Very Low Risk Chest Pain

Open Access Emergency Medicine, 2023
Maria Lucia Mosso,1 Sara Montemerani2 1S.C. Medicina e Chirurgia d’Accettazione ed Urgenza (MeCAU) – Pronto Soccorso, Dipartimento Emergenza Urgenza. Ospedale S.
Mosso ML, Montemerani S
doaj  

Randomized Trial of the Effects of Insulin and Metformin on Myocardial Injury and Stress in Diabetes Mellitus: A Post Hoc Exploratory Analysis

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2017
BackgroundSubclinical myocardial injury, as measured by high‐sensitivity cardiac troponin T (hsTnT), and myocardial stress, as measured by N‐terminal pro‐B‐type natriuretic peptide (NT‐proBNP), are related to glycemic control in patients with type 2 ...
Pratyaksh K. Srivastava, Aruna D. Pradhan, Nancy R. Cook, Paul M Ridker, Brendan M. Everett   +4 more
doaj   +1 more source