Results 111 to 120 of about 230,788 (365)

Troponins in Renal Dysfunction [PDF]

The International Journal of Artificial Organs, 2000
“I have yet to see any problem, however complicated, which, when you looked at it in the right way, did not become still more complicated.” Poul (William) Anderson
openaire   +3 more sources

Generation of Nonintegrative‐Induced Pluripotent Stem Cells in Hutchinson‐Gilford Progeria Syndrome: Enhancing Aging Research

AGING MEDICINE, EarlyView.
We generated genetically stable iPSCs from HGPS patients using a nonintegrative Sendai virus method. This approach preserves cellular integrity, enhances disease modeling, and enables accurate study of Progerin‐induced cardiovascular dysfunction. Overall, it provides a reliable platform for understanding HGPS and aging‐related disease pathology and ...
Juned Kadiwala, Rameen Shakur
wiley   +1 more source

Evaluation of the Use of Different Sensitive Cardiac Biomarkers in Determining Myocardial Damage in Cows With Subclinical and Clinical Ketoses

Veterinary Medicine and Science
Background It is unclear whether the increase in BHBA concentration damages the myocardium in ketotic cows. Measurement of troponin is the gold standard in myocardial injury.
Murat Uztimür, Cennet Nur Ünal, Meltem Sağiroğlu   +2 more
doaj   +1 more source

Determining predictors of underlying etiology and clinical deterioration in patients with physiologic instability in the emergency department [PDF]

, 2013
Thesis (M.A.)--Boston UniversityShock is a critical state defined by inadequate oxygen delivery to tissues. It is well known in the critical care community that early diagnosis and treatment of shock are crucial to improving patient outcomes. However, in
Day, Danielle E.
core   +1 more source

Confinement‐Enhanced Ultrabright AIE Nanoparticles With Broad Emission for Ultrasensitive Lateral Flow Immunoassay

Aggregate, EarlyView.
Molecular confinement via polymer network allows for significant emission enhancement (80‐fold) of AIEgen with the exceptional quantum yield of 91%, and ultra‐stable photobleaching after continuous irradiation. Subsequently, by adjusting the filter bandwidth, remarkable signal amplification (2–10 folds) is achieved, and the sensitive detection was ...
Yaxin Hu, Li Xie, Lidan Chen, Zhaohui Sun, Rong Hu, Zhiming Wang, Ben Zhong Tang   +6 more
wiley   +1 more source

Metformin for non-diabetic patients with coronary heart disease (the CAMERA study): a randomised controlled trial [PDF]

, 2009
<br>Background: Metformin reduces cardiovascular risk in patients with type 2 diabetes seemingly independent of lowering blood glucose concentration. We assessed the cardiovascular effects of metformin in individuals without type 2 diabetes.</br&
Eddy, Despres, Grundy, Bird, Seifarth, Nathan, Fontbonne, Charles, Holman, Kooy, Knowler, Alberti, Vergeer, Touboul, Liang, Spence, Levey, Meaney, Taylor, Selvin, Boussageon, Sjöström, Shyangdan, de Jager, Bots, Taylor, Boden, Huang, Baigent, Lorenz, Mazzone, Taylor, Lonn, Lexis   +33 more
core   +5 more sources

The HRAS Variant c.175G>A (p.Ala59Thr) Causes a Predominantly Ectodermal Phenotype Lacking Classic Costello Syndrome Features

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Costello syndrome (CS) is a rare dominant HRAS RASopathy characterized by curly hair, cardiac abnormalities, craniofacial anomalies, and developmental delay. HRAS codon 58, 59, and 60 variants are associated with milder phenotypes. We describe a three‐generation family with a previously unreported heterozygous HRAS variant c.175G>A (p.Ala59Thr)
Nikole Rautiainen, Eveliina Brandt, Kaisa Kettunen, Outi Elomaa, Sirpa Kivirikko, Leila Jeskanen, Katriina Lappalainen, Nelli Sjöblom, Juha Kere, Katariina Hannula‐Jouppi, Liisa Harjama   +10 more
wiley   +1 more source

Providing Rapid Out of Hospital Acute Cardiovascular Treatment 4 (PROACT‐4)

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2015
Background Whether prehospital point‐of‐care (POC) troponin further accelerates the time to diagnosis in patients with chest pain (CP) is unknown. We conducted a randomized trial of POC‐Troponin testing in the ambulance. Methods and Results Patients with
Justin A. Ezekowitz, Robert C. Welsh, Dale Weiss, Michael Chan, William Keeble, Fadi Khadour, Sanjay Sharma, Wayne Tymchak, Sunil Sookram, Neil Brass, Darren Knapp, Thomas L. Koshy, Yinggan Zheng, Paul W. Armstrong   +13 more
doaj   +1 more source

High‐Sensitivity Troponin I Levels and Coronary Artery Disease Severity, Progression, and Long‐Term Outcomes

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2018
BackgroundThe associations between high‐sensitivity troponin I (hsTnI) levels and coronary artery disease (CAD) severity and progression remain unclear.
Ayman Samman Tahhan, Pratik Sandesara, Salim S. Hayek, Muhammad Hammadah, Ayman Alkhoder, Heval M. Kelli, Matthew Topel, Wesley T. O'Neal, Nima Ghasemzadeh, Yi‐An Ko, Mohamad Mazen Gafeer, Naser Abdelhadi, Fahad Choudhary, Keyur Patel, Agim Beshiri, Gillian Murtagh, Jonathan Kim, Peter Wilson, Leslee Shaw, Viola Vaccarino, Stephen E. Epstein, Laurence Sperling, Arshed A. Quyyumi   +22 more
doaj   +1 more source

Treatment of dogs with compensated myxomatous mitral valve disease with spironolactone-a pilot study [PDF]

, 2017
Spironolactone improves outcome in dogs with advanced myxomatous mitral valve disease (MMVD). Its efficacy in preclinical MMVD is unknown. The hypothesis was the administration of spironolactone to dogs with compensated MMVD demonstrating risk factors ...
Boswood, A, Elliott, J, Hezzell, M J, Lopez-Alvarez, J, Lotter, N S   +4 more
core   +3 more sources