Results 181 to 190 of about 172,067 (306)

Recent Advances in Top‐Down Proteomics for Single‐Cell Research

Mass Spectrometry Reviews, EarlyView.
ABSTRACT Individual cells have distinctive molecular characteristics, including biologically relevant proteoforms. Although single‐cell (SC) molecular omics offer unprecedented insights into cellular heterogeneity and function, the characterization of proteoforms in SCs remains an uncharted territory.
Jake A. Melby, Pei Su, Fabio P. Gomes
wiley   +1 more source

The HEART score has less utility with high sensitivity troponin. [PDF]

Front Cardiovasc Med
Harris A, Heier K, Spindel JF, McCowan W, Slade E, Parekh M, Samadi D, Gupta V.   +7 more
europepmc   +1 more source

Proteoforms in Disease: Biomedical Applications of Top‐Down Proteomics

Mass Spectrometry Reviews, EarlyView.
ABSTRACT The proteome is a dynamic landscape of proteoforms arising from genetic mutations, alternative splicing, and post‐translational modifications (PTMs), which collectively drive biological function and disease phenotypes. Mass spectrometry (MS)‐based proteomics has emerged as an essential technique for elucidating this molecular complexity ...
Holden T. Rogers, Zachery R. Gregorich, Megan S. Gant, Zhan Gao, Julia Chamot‐Rooke, Ying Ge   +5 more
wiley   +1 more source

High-sensitivity Cardiac Troponin I Changes Following Subcutaneous Needle Puncture, Restraint, and Venipuncture in Cynomolgus Monkeys. [PDF]

In Vivo
Taniguchi Y, Iwakiri T, Yoshikawa T, Yamada T, Kawaguchi H.   +4 more
europepmc   +1 more source

Harnessing Aggregation‐Induced Emission for Advanced Disease Diagnosis: Mechanisms, Strategies and Future Perspectives

Medicine Bulletin, EarlyView.
The figure was created in BioRender.com. ABSTRACT Accurate and early diagnosis remains a key challenge in modern disease management. Conventional diagnostic methods often suffer from limitations in sensitivity, spatial resolution, and practical usability.
Zizhuo Du, Li Song, Xingrui Chen, Jun Jing, Yingchen Wang, Yue Jiang, Jiahui Gao, Dan Li, Feiran Xie, Peihong Xiao, Ben Zhong Tang   +10 more
wiley   +1 more source

Serial Cardiac Troponin I Kinetics Do Not Improve Detection of Acute Cellular Rejection Beyond Concurrent Troponin Levels After Heart Transplantation. [PDF]

J Clin Med
Ochman M, Bilnik B, Cielecka M, Zakliczyński M.   +3 more
europepmc   +1 more source

A Multidomain Prediction Model Integrating Myocardial Injury, Ventricular Function, and Inflammation for Short-Term Risk Stratification in Patients with NSTEMI. [PDF]

Clin Pract
Bećirović E, Bećirović M, Bećirović A, Tursunović A, Bajrić A, Softić A, Mujkić A, Mujaković E, Abdić A, Ferhatbegović L.   +9 more
europepmc   +1 more source

Just be the parent

Journal of Hospital Medicine, EarlyView.
Andrew S. Kern‐Goldberger
wiley   +1 more source

Emergencies in Amyotrophic Lateral Sclerosis

Muscle &Nerve, EarlyView.
ABSTRACT Emergencies are frequent in people living with amyotrophic lateral sclerosis (pALS), especially as the disease progresses, and can necessitate urgent evaluation and intervention. Progressive weakness in ALS inevitably increases fall risk, making discussion of fall prevention strategies integral to caring for pALS.
S. Pinar Uysal, Katherine A. Dudley, Stacey Sullivan, Kate T. Brizzi, Katherine M. Burke, Sydney Hall, Kiersten Pease, Joshua N. Goldstein, James D. Berry, Doreen T. Ho   +9 more
wiley   +1 more source

Troponin T clearance via continuous renal replacement therapies in the ICU. [PDF]

J Intensive Care
Boyd S, Mason S, Griffin S, Pereppadan B, Moyles S, Reddy K, Keane C, Begley E, Deasy E, Donnelly M, Chevarria J, D'Arcy DM, Kelly YP.   +12 more
europepmc   +1 more source