Adaptative Steered Molecular Dynamics Study of Mutagenesis Effects on Calcium Affinity in the Regulatory Domain of Cardiac Troponin C. [PDF]
Hantz ER, Lindert S.
europepmc +1 more source
A comprehensive guide to genetic variants and post-translational modifications of cardiac troponin C. [PDF]
Reinoso TR+8 more
europepmc +1 more source
A Better Upper Bound of Hausdorff Measure of the Cartesian Product of the Middle Third Cantor Set with Itself Compare to Others' [PDF]
After the correction of an inaccurate result in the reference, the author uses five different methods, and gets five different inequalities on the Hausdorff measure of the Cartesian product of the middle third Cantor set with itself: $$H^s (C\times C)\leq 1.548563$$ $$H^s (C\times C)\leq 1.504975$$ $$H^s (C\times C)\leq 1.502878$$ $$H^s (C\times C)\leq
arxiv
Anomalous structural dynamics of minimally frustrated residues in cardiac troponin C triggers hypertrophic cardiomyopathy. [PDF]
Marques MA+14 more
europepmc +1 more source
A note on duality theorems in mass transportation [PDF]
The duality theory of the Monge-Kantorovich transport problem is investigated in an abstract measure theoretic framework. Let $(\mathcal{X},\mathcal{F},\mu)$ and $(\mathcal{Y},\mathcal{G},\nu)$ be any probability spaces and $c:\mathcal{X}\times\mathcal{Y}\rightarrow\mathbb{R}$ a measurable cost function such that $f_1+g_1\le c\le f_2+g_2$ for some $f_1,
arxiv
Molecular mechanisms of the regulation of ATPase cycle in striated muscle [PDF]
New data on the molecular mechanism of the regulation of ATPase cycle by troponin-tropomyosin system have been obtained in reconstructed muscle fibers by using the polarized fluorescence technique, which allowed us following the azimuthal movements of ...
Charles S. Redwood+2 more
core +1 more source
ECG-FM: An Open Electrocardiogram Foundation Model [PDF]
The electrocardiogram (ECG) is a ubiquitous diagnostic test. Conventional task-specific ECG analysis models require large numbers of expensive ECG annotations or associated labels to train. Transfer learning techniques have been shown to improve generalization and reduce reliance on labeled data.
arxiv
A One Health Approach to Hypertrophic Cardiomyopathy. [PDF]
Hypertrophic cardiomyopathy (HCM) is the most common inherited cardiac disease in humans and results in significant morbidity and mortality. Research over the past 25 years has contributed enormous insight into this inherited disease particularly in the ...
Stern, Joshua A, Ueda, Yu
core +1 more source
Impact on clinical guideline adherence of Orient-COVID, a CDSS based on dynamic medical decision trees for COVID19 management: a randomized simulation trial [PDF]
Background: The adherence of clinicians to clinical practice guidelines is known to be low, including for the management of COVID-19, due to their difficult use at the point of care and their complexity. Clinical decision support systems have been proposed to implement guidelines and improve adherence.
arxiv
Contemporary NSTEMI management: the role of the hospitalist. [PDF]
Non-ST-segment elevation myocardial infarction (NSTEMI) is defined as elevated cardiac biomarkers of necrosis in the absence of persistent ST-segment elevation in the setting of anginal symptoms or other acute event.
Amin, Alpesh+9 more
core +1 more source