Results 101 to 110 of about 18,693,880 (254)

Bovine cardiac troponin subunits: binary complexes and reconstitution of whole troponin [PDF]

, 1982
The reconstitution of bovine cardiac troponin from its subunits has been investigated using hydrodynamic techniques. Gel filtration (Sephacryl S-300) and sedimentation velocity experiments indicate that troponin-C and troponin-I from a stable binary ...
Kay, Cyril M., Cyril M. Kay, David M. Byers, Byers, David M.   +3 more
core   +1 more source

Use of Intracoronary Pressure Wire Assessment and Association With Outcomes: Insights From the British Cardiovascular Intervention Society National Database

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Despite recommendations in international guidelines, Intracoronary pressure wire assessment (PWA) utilization remains limited in clinical practice. This study aims to describe (i) trends of PWA during Percutaneous coronary interventional (PCI), (ii) factors that predict its application, and (iii) association with in‐hospital ...
Hussein Bashar, Muhammad Rashid, Mamas A. Mamas, Nick Curzen   +3 more
wiley   +1 more source

Thermodynamic studies of Ca²? binding to human cardiac troponin C

, 2023
Human Cardiac Troponin C (HcTnC) is an EF hand protein responsible for initiating contraction of the myocardium (heart muscle). The helix-loop-helix motif, characteristic of members of the EF-hand family, allows HcTnC to act as a Ca²?
Skowronsky, Rachel Ann, NC DOCKS at East Carolina University   +1 more
core  

Novel Use of Intravascular Lithotripsy for the Mobilization of an Entrapped Coronary Guidewire in a Heavily Calcified LAD/DB Bifurcation Lesion—A Case Report

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT A 64‑year‑old man with a Non–ST‑elevation myocardial infarction (NSTEMI) underwent coronary angiography, which revealed single‑vessel disease with a high‑grade proximal and a severely calcified mid‑LAD lesion just proximal to a diagonal branch (DB). Both the LAD and the DB were wired.
Hansmartin Jetter, Jochen Genzel, Wolfram Voelker   +2 more
wiley   +1 more source

Structure and proteolytic susceptibility of the inhibitory C-terminal tail of cardiac troponin I

, 2019
Background Cardiac troponin I (cTnI) has two flexible tails that control the cardiac cycle. The C-terminal tail, cTnI135-209, binds actin to shut off cardiac muscle contraction, whereas the competing calcium-dependent binding of the switch region ...
Reiz, Bela, Zahran, Somaya, McCartney, Christian-Scott E., Li, Liang, Hwang, Peter M., Liu, Philip B., Roczkowsky, Andrej, Davies, Peter L., Chan, Brandon Y.H., Mahmud, Zabed, Schulz, Richard   +10 more
core   +1 more source

Incidence of Periprocedural Myocardial Injury and Infarction After Intravascular Lithotripsy for Calcified Coronary Artery Stenosis

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Intravascular lithotripsy (IVL) has emerged as an effective technique for modifying heavily calcified coronary plaques, facilitating optimal stent expansion while minimizing procedural complications. However, data on periprocedural myocardial injury (PMI) and infarction (PPMI) following IVL remain scarce.
Gwaenaelle Aellen, Dorian Garin, Yannick Faucherre, Serban Puricel, Mario Togni, Stéphane Cook   +5 more
wiley   +1 more source

Cardiac Manifestations and Emerging Biomarkers in Multisystem Inflammatory Syndrome in Children (MIS-C): A Systematic Review and Meta-Analysis

Life
Background: Cardiac involvement is a key prognostic factor in multisystem inflammatory syndrome in children (MIS-C), a rare but serious inflammatory condition that typically occurs 2–6 weeks after SARS-CoV-2 infection and is characterized by fever ...
Diana-Andreea Ciortea, Mădălina Nicoleta Matei, Mihaela Debita, Ancuța Lupu, Mirela Mătăsaru, Gabriela Isabela Verga (Răuță), Silvia Fotea   +6 more
doaj   +1 more source

Assembly and Maintenance of Myofibrils in the Heart

Cytoskeleton, EarlyView.
ABSTRACT The assembly of actin and myosin to the paracrystalline arrangement of myofibrils in striated muscle, that is, heart and skeletal, has puzzled many a cell biologist. Different models, based on cultured cardiomyocytes, were proposed for the last 30 years to explain the sequence of events.
Elisabeth Ehler
wiley   +1 more source

Fixation Induces Mislocalization of Thin Filament Components in Caenorhabditis elegans Striated Muscle

Cytoskeleton, EarlyView.
ABSTRACT The simple nematode Caenorhabditis elegans has long served as a powerful genetic model system for studying muscle structure and function, with sarcomeres of the striated body wall muscle (BWM) that are considered largely homologous to those in vertebrates.
Michael J. Kimmich, Pu Zhang, Bob Goldstein, David Pruyne   +3 more
wiley   +1 more source

Evaluation of the utility of cardiac biomarkers for risk stratification in patients with lower extremity artery disease: A retrospective study.

PLoS ONE
Critical limb threatening ischemia (CLTI) is associated with a one-year mortality rate of up to 25% making prompt diagnosis essentially. This study aims to investigate if cardiac biomarkers may serve as an effective tool for risk stratification in ...
Leyla Schweiger, Reinhard B Raggam, Gabor Toth-Gayor, Philipp Jud, Alexander Avian, Viktoria Nemecz, Katharina Gütl, Marianne Brodmann, Thomas Gary   +8 more
doaj   +1 more source