Biological activities of the peptides obtained by digestion of troponin C and calmodulin with thrombin [PDF]
C. M. Wall, Roger J.A. Grand, S V Perry
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A comprehensive guide to genetic variants and post-translational modifications of cardiac troponin C. [PDF]
Reinoso TR +8 more
europepmc +1 more source
Solution Structures of the C-Terminal Domain of Cardiac Troponin C Free and Bound to the N-Terminal Domain of Cardiac Troponin I, [PDF]
Geneviève M. C. Gasmi-Seabrook +7 more
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Critical limb threatening ischemia (CLTI) is associated with a one-year mortality rate of up to 25% making prompt diagnosis essentially. This study aims to investigate if cardiac biomarkers may serve as an effective tool for risk stratification in ...
Leyla Schweiger +8 more
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Adaptative Steered Molecular Dynamics Study of Mutagenesis Effects on Calcium Affinity in the Regulatory Domain of Cardiac Troponin C. [PDF]
Hantz ER, Lindert S.
europepmc +1 more source
Determining predictors of underlying etiology and clinical deterioration in patients with physiologic instability in the emergency department [PDF]
Thesis (M.A.)--Boston UniversityShock is a critical state defined by inadequate oxygen delivery to tissues. It is well known in the critical care community that early diagnosis and treatment of shock are crucial to improving patient outcomes. However, in
Day, Danielle E.
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Cardiac remodelling in the era of the recommended four pillars heart failure medical therapy
Abstract Cardiac remodelling is a key determinant of worse cardiovascular outcome in patients with heart failure (HF) and reduced ejection fraction (HFrEF). It affects both the left ventricle (LV) structure and function as well as the left atrium (LA) and the right ventricle (RV).
Giada Colombo +7 more
wiley +1 more source
Cardiomyocyte Nuclear Pleomorphism in a Mouse Model of Inherited Hypertrophic Cardiomyopathy
Mutations in genes encoding sarcomeric proteins are a common cause of cardiomyopathy and sudden cardiac death in humans. We evaluated the hypothesis that myofilament dysfunction is coupled to morphological and functional alterations of cardiomyocyte ...
Jamie R. Johnston +18 more
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Anomalous structural dynamics of minimally frustrated residues in cardiac troponin C triggers hypertrophic cardiomyopathy. [PDF]
Marques MA +14 more
europepmc +1 more source
Borderline Values of Troponin-T and High Sensitivity C-Reactive Protein Did Not Predict 2-Year Mortality in TnT Positive Chest-Pain Patients, Whereas Brain Natriuretic Peptide Did [PDF]
Dennis W Nilsen +8 more
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