Results 231 to 240 of about 19,854,960 (401)

Effect of calcium-sensitizing mutations on calcium binding and exchange with troponin C in increasingly complex biochemical systems.

open access: yesBiochemistry, 2010
S. Tikunova   +6 more
semanticscholar   +1 more source

A new staging system for hereditary transthyretin amyloidosis in the era of specific amyloidosis therapies

open access: yesESC Heart Failure, EarlyView.
The aim of our study was to develop a more accurate staging system for hereditary ATTR patients currently receiving specific treatment. A staging system was created using as criteria: GLS ≤ −11%, NT‐proBNP ≤ 2,000 ng/L, and eGFR ≤ 65 mL/min. We managed to accurately stratify patients into three disease stages, significantly different in terms of ...
Gabriela Neculae   +7 more
wiley   +1 more source

Galectin‐3 and kidney function in type 2 diabetes treated with dapagliflozin: Analysis from DECLARE‐TIMI 58

open access: yesESC Heart Failure, EarlyView.
Abstract Background Galectin‐3 (Gal‐3) is a circulating biomarker of fibrosis, with higher levels being associated with an increased risk of progression of heart failure and kidney disease. Patients with type 2 diabetes mellitus (T2DM) are at increased risk of both.
Paul M. Haller   +12 more
wiley   +1 more source

Kinetic Studies of Calcium Binding to the Regulatory Site of Troponin C from Cardiac Muscle [PDF]

open access: hybrid, 1996
Wen-ji Dong   +4 more
openalex   +1 more source

Percutaneous endocardial alginate–hydrogel injection in the treatment of heart failure: First‐in‐human study

open access: yesESC Heart Failure, EarlyView.
Using EndoWings™ and XDROP™, we developed a percutaneous minimally invasive technique for sequential circumferential alginate hydrogel injection into LV free mid‐wall. This human study assessed its safety/feasibility in HFrEF patients, with personalised biomechanical models.
Bo Wang   +13 more
wiley   +1 more source

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