Results 241 to 250 of about 162,145 (312)

Clinical Impact of Macrotroponin on Immunometric Troponin Assays: A Cross-Analytical Case Evaluation. [PDF]

open access: yesInt J Mol Sci
Salvatici M   +7 more
europepmc   +1 more source

Computed Tomography Yield and Predictors of Pulmonary Embolism in Mechanically Ventilated Patients—A Retrospective Study

open access: yesActa Anaesthesiologica Scandinavica, Volume 70, Issue 4, April 2026.
ABSTRACT Background The reported prevalence of pulmonary embolism (PE) detected during intensive care varies substantially. Computed tomography pulmonary angiography (CTPA) is the diagnostic reference method, but assessing pre‐test probability and finding distinct indications for CTPA from clinical observations is difficult in mechanically ventilated ...
Erik Bruno   +6 more
wiley   +1 more source

Targeting inflammation in cardiometabolic disease: Icosapent ethyl modulates monocyte‐derived macrophages isolated from patients with cardiovascular disease with or without type 2 diabetes

open access: yesDiabetic Medicine, Volume 43, Issue 4, April 2026.
Abstract Aims Despite intensive lipid‐lowering therapy, individuals with atherosclerotic cardiovascular disease (ASCVD) exhibit residual inflammatory risk, which drives recurrent cardiovascular events. This risk is amplified in type 2 diabetes mellitus (T2DM), where a pro‐inflammatory milieu accelerates atherogenesis. Monocyte‐derived macrophages (MDMs)
J. K. Ward   +4 more
wiley   +1 more source

Diabetic kidney disease, biomarkers, and finerenone

open access: yesDiabetes, Obesity and Metabolism, Volume 28, Issue 4, Page 2582-2593, April 2026.
Abstract Diabetic kidney disease (DKD), the leading cause of kidney failure worldwide, is associated with an increased risk of cardiovascular disease (CVD). A complex pathobiology involving hemodynamic, metabolic, and immune dysregulation promotes inflammatory and fibrotic pathways that contribute to kidney disease progression and CVD in individuals ...
Ashish Verma, Ashish Upadhyay
wiley   +1 more source

Targeting Expanded CUG and CTG Repeats as a Therapeutic Approach for Myotonic Dystrophy Type 1 (DM1)

open access: yesChemMedChem, Volume 21, Issue 5, 13 March 2026.
DM1 is an RNA gain‐of‐function disease caused by CTG repeat expansion, producing toxic r(CUG)exp RNA that sequesters MBNL1 and impairs splicing. This review covers the field of CUG and CTG ligands identified or rationally designed as DM1 drug candidates, highlighting their molecular design, RNA‐ or DNA‐binding modes, in vitro affinities and ...
Camille Richagneux, Anton Granzhan
wiley   +1 more source

Long forms of cardiac troponin T for myocardial infarction diagnosis: the SuperTROPO study. [PDF]

open access: yesEur Heart J
Teppo K   +13 more
europepmc   +1 more source

Diagnostic performance of the Myocardial-Ischaemic-Injury index machine-learning algorithm in patients with an initial indeterminate troponin. [PDF]

open access: yesOpen Heart
Snavely AC   +8 more
europepmc   +1 more source

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