Results 271 to 280 of about 19,667,204 (333)

Roles of nanomagnetic beads on biosensing: From fabrication to application

Interdisciplinary Medicine, EarlyView.
Leveraging their intrinsic superparamagnetic properties and rapid magnetic responsiveness, functionalized nanomagnetic beads have emerged as pivotal platforms in advanced biosensing system. Through surface engineering and structural design, these magnetic nanoparticles demonstrate multi‐capabilities, such as sample separation, signal enhancement, and ...
Junjie Li, Liyang Duan, Qian Chen, Songsong Huang, Weixia Li, Huachu Zuo, Shuang Li, Wei Han, Wei Fu, Shike Hou, Bin Fan, Zetao Chen   +11 more
wiley   +1 more source

Calcium Binding Properties of C. elegance Troponin C Mutant

, 2000
T. Ueda, Y. Kajiwara, O. Yoshioka, Hirotaka Katuzaki, Toshiro Murase, H. Terami, Hiroaki Kagawa, Iio T   +7 more
openalex   +2 more sources

The Interplay of Ontogeny and Phylogeny at the Transcriptome Level of the Tetrapod Heart

Journal of Experimental Zoology Part B: Molecular and Developmental Evolution, EarlyView.
The main stages of development during which species‐specific heart anatomy is determined in the ontogeny of representative tetrapods. Transcriptomic similarity is expected earlier in development before heart anatomy diverges. ABSTRACT The tetrapod heart is characterized by three chambers in amphibians and non‐avian reptiles, as opposed to four in birds,
G. A. Cordero, A. K. Holloway, T. Friedrich, J. Eme, W. Eckalbar, K. Kusumi, F. J. Janzen, J. W. Hicks, F. L. Conlon, B. G. Bruneau, K. S. Pollard   +10 more
wiley   +1 more source

Effects of Sarcomere Length and Ca2+ Binding on SH Reactivity of Myofilament Bound Troponin C in Porcine Skinned Cardiac Muscle Fibers.

, 2001
Ying‐Ming Liou
openalex   +2 more sources

Proteomic Profiling Informs Mechanisms of Esophageal Adenocarcinoma Inhibition by Cranberry Proanthocyanidins

Molecular Nutrition &Food Research, EarlyView.
In this study we utilized proteomic profiling to investigate mechanisms linked to the cancer‐inhibitory effect of cranberry proanthocyanidins (CPACs) on reflux‐induced esophageal adenocarcinoma in a rat model. The results indicate that CPAC inhibits cancer through targeting multiple hallmarks of cancer known to be dysregulated in progression to ...
Yun Zhang, Michelle Lee, Erika de Jesus, Katherine Weh, Connor Howard, Henriette Remmer, Amy B. Howell, Laura A. Kresty   +7 more
wiley   +1 more source

A Phase 1, Double‐Blind, Placebo‐Controlled Trial of Sevasemten (EDG‐5506), a Selective Modulator of Fast Skeletal Muscle Contraction, in Healthy Volunteers and Adults With Becker Muscular Dystrophy

Muscle &Nerve, EarlyView.
ABSTRACT Introduction/Aims Sevasemten (EDG‐5506) is an orally administered, investigational small molecule that selectively modulates fast muscle fiber contraction by inhibiting fast myosin ATPase. This study assessed the safety, tolerability, and pharmacokinetics (PK)/pharmacodynamics (PD) of sevasemten in healthy adult volunteers (HVs) and adults ...
Joanne Donovan, Jeffrey A. Silverman, Ben Barthel, Michael DuVall, Molly Madden, James MacDougall, Nicole Rempel Kilburn, Abby Bronson, Marc Evanchik, Gilad Gordon, Kevin Koch, Alan J Russell   +11 more
wiley   +1 more source

Serum Cardiac Troponin T Levels as a Therapy Response Marker in Tofersen‐Treated ALS

Muscle &Nerve, EarlyView.
ABSTRACT Introduction/Aims Cardiac troponin T (cTnT) levels are elevated in the majority of persons with amyotrophic lateral sclerosis (ALS) and increase over time. Neurofilament light chain (NfL) is an established therapy response biomarker in ALS as superoxide dismutase1 (SOD1)‐ALS patients treated with the antisense oligonucleotide tofersen show a ...
Sarah Bernsen, Rachel Fabian, Yasemin Koc, Peggy Schumann, Peter Körtvélyessy, Sergio Castro‐Gomez, Thomas Meyer, Patrick Weydt   +7 more
wiley   +1 more source

Post‐COVID‐19 condition: clinical phenotypes, pathophysiological mechanisms, pathology, and management strategies

The Journal of Pathology, EarlyView.
Abstract Post‐COVID‐19 condition (PCC), also known as long COVID, is a complex multiple organ system condition that can develop and persist for months after acute COVID‐19. PCC encompasses a wide range of symptoms, resulting in heterogeneous clinical manifestations. These manifestations likely arise from diverse underlying pathophysiological mechanisms,
Larissa E Vlaming‐van Eijk, Guolu Tang, Arno R Bourgonje, Wilfred F A den Dunnen, Jan‐Luuk Hillebrands, Harry van Goor   +5 more
wiley   +1 more source

Predictors of and outcomes related to perioperative myocardial injury post‐tracheotomy

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
Abstract Introduction Perioperative myocardial injury (PMI) is associated with increased mortality. We describe risk factors for and outcomes of PMI in patients undergoing tracheotomy. Methods Retrospective study of patients undergoing tracheotomy from 2007 to 2016.
Randy W. Lesh, Jino Park, Vincent M. Desiato, Martin Matsumura, Thorsen W. Haugen   +4 more
wiley   +1 more source

Data privacy model using blockchain reinforcement federated learning approach for scalable internet of medical things

CAAI Transactions on Intelligence Technology, EarlyView.
Abstract Internet of Medical Things (IoMT) has typical advancements in the healthcare sector with rapid potential proof for decentralised communication systems that have been applied for collecting and monitoring COVID‐19 patient data. Machine Learning algorithms typically use the risk score of each patient based on risk factors, which could help ...
Chandramohan Dhasaratha, Mohammad Kamrul Hasan, Shayla Islam, Shailesh Khapre, Salwani Abdullah, Taher M. Ghazal, Ahmed Ibrahim Alzahrani, Nasser Alalwan, Nguyen Vo, Md Akhtaruzzaman   +9 more
wiley   +1 more source