Results 291 to 300 of about 19,854,960 (401)

Mapping subdomains in the C-terminal region of troponin I involved in its binding to troponin C and to thin filament.

, 2000
Carlos H.I. Ramos
openalex   +1 more source

Comparative Evaluation of Centrifugation Speed and Its Impact on Diagnostic Accuracy

Journal of Clinical Laboratory Analysis, EarlyView.
This study evaluates whether high‐speed centrifugation (5 min at 4000 g) can effectively reduce laboratory turnaround time (TAT) without compromising diagnostic accuracy. Results showed that most analytes remained clinically reliable, hemolysis rates were significantly reduced, and the faster method proved to be a safe and efficient alternative for ...
Mohammed A. Jeraiby, Jobran M. Moshi, Sajad A. Dar, Mahmoud M. Habibullah, Mjery Yahia, Saif Elden B. Abdalla, Raheem M. Balkhtab, Renad A. Saigh, Nahlah S. burayk   +8 more
wiley   +1 more source

Exposure–Response Modeling and Simulation to Identify Optimal Mavacamten Posology When Coadministered with CYP3A4 and CYP2C19 Inhibitors in Patients with Obstructive HCM

The Journal of Clinical Pharmacology, EarlyView.
Abstract Mavacamten, a cardiac myosin inhibitor, is primarily metabolized by the cytochrome P450 (CYP) enzymes CYP2C19 and CYP3A4, and coadministration with strong CYP3A4 or CYP2C19 inhibitors was contraindicated in patients with obstructive hypertrophic cardiomyopathy (HCM) in the US Prescribing Information. This study assessed the safety and efficacy
Samira Merali, Haden Bunn, Caroline Sychterz, Manting Chiang, Shilpa Puli, Amy J. Sehnert, Bindu Murthy, Joga Gobburu   +7 more
wiley   +1 more source

Toward Understanding the Molecular Bases of Stretch Activation: A STRUCTURAL COMPARISON OF THE TWO TROPONIN C ISOFORMS OF LETHOCERUS. [PDF]

J Biol Chem, 2016
Sanfelice D, Sanz-Hernández M, de Simone A, Bullard B, Pastore A.   +4 more
europepmc   +1 more source

Calcium Binding Properties of C. elegance Troponin C Mutant

, 2000
T. Ueda, Y. Kajiwara, O. Yoshioka, Hirotaka Katuzaki, Toshiro Murase, H. Terami, Hiroaki Kagawa, Iio T   +7 more
openalex   +2 more sources

Unexpected Giant Right Coronary Artery Aneurysm Diagnosed by Computed Tomography Angiography in the Emergency Department

Journal of Clinical Ultrasound, EarlyView.
3D Volume Rendering coronary CTA reconstruction showing a giant thrombosed aneurysm of the proximal right coronary artery ABSTRACT Giant coronary artery aneurysms (GCAA) are usually defined as diameter > 8 mm or > 400% of the adjacent normal segment; they are very rare (reported prevalence ≈0.02%).
Stefano Giusto Picchi, Giulia Lassandro, Rosita Comune, Filomena Pezzullo, Stefania Tamburrini, Giulio Cocco, Nino Cocco, Domenico Tafuri, Antonio Corvino   +8 more
wiley   +1 more source

Changes in remnant cholesterol levels after coronary angiography: inflammation and cardiovascular risk assessment. [PDF]

Rev Assoc Med Bras (1992)
Dikme R, Padak M, Güler Y, Sarpkaya A, Göç Ö, Çiçek ÖF.   +5 more
europepmc   +1 more source

The Utility of Troponin in Predicting Cardiac Dysfunction in Pediatric Patients: A Meta-Analysis. [PDF]

Cureus
Kadakia R, Muntean C, Klein LR, Eckardt S, Kalin CE, Rothburd L, Caronia C, Eckardt PA.   +7 more
europepmc   +1 more source

Mitigating Trastuzumab‐Doxorubicin Cardiotoxicity With Multiscale Quantitative Systems Toxicology and PBPK‐Toxicodynamic Predictive Modeling Framework

CPT: Pharmacometrics &Systems Pharmacology, EarlyView.
ABSTRACT Doxorubicin (DOX) and trastuzumab (TmAb) are widely used to treat HER2‐positive breast cancer (BC), as monotherapies and in combination (DOX + TmAb). While highly effective, their combined use significantly increases the risk of irreversible cardiotoxicity, posing a major clinical concern.
Sijia Yu, Hardik Mody, Tanaya R. Vaidya, Leonid Kagan, Sihem Ait‐Oudhia   +4 more
wiley   +1 more source

Comparison of risk factors and outcomes of raised vs normal cardiac troponin levels in COVID-19 patients: a retrospective study. [PDF]

Sci Rep
Ahmed I, Syed B, Sayeed MA, Farooqui F, Abbas U, Afshan S, Zaidi SK, Farman S, Khan M, Hussain N, Hadif M, Khalid MU, Fatima K, Mubeen M.   +13 more
europepmc   +1 more source