Results 321 to 330 of about 166,646 (357)

Interactions among chymotryptic troponin T subfragments, tropomyosin, troponin I and troponin C.

Journal of biochemistry, 1984
The binding of various combinations of chymotryptic troponin T subfragments, troponin I and troponin C to tropomyosin, troponin C and troponin I was examined semiquantitatively by using affinity chromatography. The interaction between troponin T2 and troponin I intensified the interaction between troponin T2 (or troponin T) and tropomyosin.
M, Tanokura, I, Ohtsuki
openaire   +1 more source

Interaction of troponin I and troponin C: ¹⁹F NMR studies of the binding of the inhibitory troponin I peptide to turkey skeletal troponin C

Biochemistry and Cell Biology, 1991
We have used 19F nuclear magnetic resonance spectroscopy to study the interaction of the inhibitory region of troponin (TnI) with apo- and calcium(II)-saturated turkey skeletal troponin C (TnC), using the synthetic TnI analogue Nα-acetyl[19FPhe106]TnI(104–115)amide.
A P, Campbell, P J, Cachia, B D, Sykes
openaire   +2 more sources

Proximity Relationships between Residue 6 of Troponin I and Residues in Troponin C:  Further Evidence for Extended Conformation of Troponin C in the Troponin Complex

Biochemistry, 2000
Skeletal muscle troponin C (TnC) adopts an extended conformation when crystallized alone and a compact one when crystallized with an N-terminal troponin I (TnI) peptide, TnI(1-47) [Vassylyev et al. (1998) Proc. Natl. Acad. Sci. U.S.A. 95, 4847-4852]. The N-terminal region of TnI (residues 1-40) was suggested to play a functional role of facilitating ...
Y, Luo, J, Leszyk, B, Li, J, Gergely, T, Tao   +4 more
openaire   +2 more sources

Magnesium–Calcium Exchange in Cardiac Troponin C Bound to Cardiac Troponin I

Journal of Molecular and Cellular Cardiology, 2000
Understanding the process of Ca(2+)/Mg(2+)exchange during muscle excitation and relaxation is fundamental to elucidating the mechanism of Ca(2+)-regulated muscle contraction. During the resting phase, the C-domain of cardiac troponin C may be occupied by either Ca(2+)or Mg(2+).
N, Finley, A, Dvoretsky, P R, Rosevear
openaire   +2 more sources

Troponin C — Troponin I Interactions and Molecular Signalling in Cardiac Myofilaments

1995
This chapter describes a current perception of the molecular interactions regulating myofilament activity in heart cells. The focus is on the interaction between troponin-C (TnC), the Ca(2+)-receptor and troponin I (TnI), an inhibitory protein. It is this interaction that appears to form a molecular switch that turns on the thin filament.
openaire   +2 more sources

Interaction of troponin I and troponin C

Journal of Molecular Biology, 1991
A.Patricia Campbell, Brian D. Sykes
openaire   +1 more source

Conformational Change of Troponin T Induced by Calcium Binding to Troponin C

The Journal of Biochemistry, 1985
The skeletal muscle troponin complex, the troponin T subunit of which was labeled with 2-((4'-iodoacetamido)anilino)naphthalene-6-sulfonic acid, showed a fluorescence titration curve with a midpoint of around pCa 6.75. Addition of 2 mM MgCl2 had no effect on the fluorescence titration curve.
openaire   +2 more sources

Machine learning for diagnosis of myocardial infarction using cardiac troponin concentrations

Nature Medicine, 2023
Dimitrios Doudesis, Kuan Ken Lee, Jasper Boeddinghaus   +2 more
exaly  

Unfolding Troponin–C

Nature, 1978
openaire   +2 more sources

Patterns of myocardial injury in recovered troponin-positive COVID-19 patients assessed by cardiovascular magnetic resonance

European Heart Journal, 2021
Tushar Kotecha, Yousuf Razvi, Kartik Kumar   +2 more
exaly