Results 261 to 270 of about 86,589 (350)

Massive reduction of RyR1 in muscle spindles of mice carrying recessive Ryr1 mutations alters proprioception and causes scoliosis

The Journal of Physiology, EarlyView.
Abstract figure legend Intrafusal muscles contained within muscle spindles are endowed with ryanodie receptor 1 (RyR1) calcium channels and participate in proprioceptor function. Mutations in RyR1 linked to severe RYR1‐congenital myopathies affect calcium release from both extrafusal as well as intrafusal muscles.
Alexis Ruiz, Sofia Benucci, Hervé Meier, Georg Schultz, Katarzyna Buczak, Christoph Handschin, Rodrigo C. G. Pena, Susan Treves, Francesco Zorzato   +8 more
wiley   +1 more source

A reconsidered diagnosis in an unresolving myocarditis-a case report. [PDF]

Eur Heart J Case Rep
Woolfenden B, Cawley C, Ward D.
europepmc   +1 more source

Fetal glucose availability: a key regulator of the metabolic, hormonal and contractility profiles of the fetal sheep heart

The Journal of Physiology, EarlyView.
Abstract figure legend To investigate the role of glucose availability in fetal left ventricle (LV) development, this study assessed whether maternal late gestation undernutrition (LGUN; 50% of Control diet) induced alterations in the contractility, metabolic, and hormonal profile can be ameliorated in LGUN fetuses receiving glucose infusion (LGUN+G ...
Melanie R. Bertossa, Jack R. T. Darby, Stacey L. Holman, Steven K. S. Cho, Ashley S. Meakin, Mitchell C. Lock, Jordan A. Minns, Michael D. Wiese, Christopher K. Macgowan, Mike Seed, Janna L. Morrison   +10 more
wiley   +1 more source

Metabolite‐sensitive cross‐bridge models of human atria reveal the impact of diabetes on muscle mechanoenergetics

The Journal of Physiology, EarlyView.
Abstract figure legend In this study, we used mathematical modelling to explore the effect of diabetes on muscle mechanoenergetics. Our parameterisation of cross‐bridge models using data from non‐diabetic and diabetic human atrial tissues revealed lower values for cross‐bridge stiffness, detachment rates, attachment rates and lower ATP sensitivity in ...
Julia H. Musgrave, June‐Chiew Han, Marie‐Louise Ward, Andrew J. Taberner, Kenneth Tran   +4 more
wiley   +1 more source

Prognostic Implications of Preoperative hs-cTnT in Elective Coronary Artery Bypass Grafting. [PDF]

JACC Adv
Pölzl L, Kletzer J, Lohmann R, Sutter C, Ioannou-Nikolaidou M, Engler C, Graber M, Nägele F, Hirsch J, Heuts S, Czerny M, Reinstadler SJ, Holfeld J, Grimm M, Fagu A, Kreibich M, Hartikainen T, Bonaros N, Berger T, Gollmann-Tepeköylü C.   +19 more
europepmc   +1 more source

14‐3‐3 proteins: Regulators of cardiac excitation–contraction coupling and stress responses

The Journal of Physiology, EarlyView.
Abstract figure legend 14‐3‐3 protein interactions in cardiac regulation. Schematic representation of 14‐3‐3 binding partners in excitation–contraction coupling, transcriptional regulation/development and stress response pathways. Asterisks indicate targets where the exact 14‐3‐3 binding site is unknown.
Heather C. Spooner, Rose E. Dixon
wiley   +1 more source

3P001 Structural Analysis of Phosphorylated Cardiac Troponin C-Troponin I Complex by Pulsed ESR(Protein: Structure,The 48th Annual Meeting of the Biophysical Society of Japan)

, 2010
Jun Abe, Yasunori Ohba, Shoji Ueki, Toshiaki Arata, Seigo Yamauchi   +4 more
openalex   +2 more sources

Heterogeneity in association of myocardial injury and mortality in sepsis or acute respiratory distress syndrome by subphenotype: a retrospective study. [PDF]

Crit Care
Sanchez PA, Obeidalla S, Kerchberger VE, Moore AR, Maddali MV, Kangelaris KN, Hendrickson CM, Evrard B, Liu KD, Bastarache JA, Matthay MA, Rogers AJ, Calfee CS.   +12 more
europepmc   +1 more source

Antioxidant supplementation blunts the proteome response to 3 weeks of sprint interval training preferentially in human type 2 muscle fibres

The Journal of Physiology, EarlyView.
Abstract figure legend Sprint interval training (SIT) is a popular time‐efficient type of endurance training. Healthy young men performed nine SIT sessions (4–6 × 30 s all‐out cycling sprints) over 3 weeks while being supplemented with antioxidants (high doses of vitamins C and E) or placebo. Muscle biopsies taken before and after the first SIT session
Victoria L. Wyckelsma, Marta Murgia, Sigitas Kamandulis, Stefano Gastaldello, Marius Brazaitis, Audrius Snieckus, Nerijus Eimantas, Mati Pääsuke, Sebastian Edman, William Apro, Daniel C. Andersson, Håkan Westerblad, Tomas Venckunas   +12 more
wiley   +1 more source

1G1624 The Effect of N-terminal Region of Cardiac Troponin I in Structural Change of Trponin C and I Complex Studied by Pulsed ESR(Protein: Structure 1,The 49th Annual Meeting of the Biophysical Society of Japan)

, 2011
Jun Abe, Shoji Ueki, Toshiaki Arata, Seigo Yamauchi, Yasunori Ohba   +4 more
openalex   +2 more sources