Results 81 to 90 of about 86,589 (350)
Relaxed and active thin filament structures; a new structural basis for the regulatory mechanism [PDF]
, 2017 The structures of muscle thin filaments reconstituted using skeletal actin and cardiac troponin and tropomyosin have been determined with and without bound Ca2+ using electron microscopy and reference-free single particle analysis.
Morris, Edward +2 more
core +1 more source
Advanced Materials, EarlyView.This study presents a novel 4D bioprinting technique for fabricating cardiac tissues with complex microvasculature. Unlike traditional 3D printing, it enables capillary‐scale structure formation via selective post‐printing shrinkage. This approach overcomes resolution limits of printing cell‐laden hydrogels, allowing the creation of functional ...
Ester Sapir Baruch +6 more
wiley +1 more source
The implementation of persuasive technology principles in mobile application development: a qualitative study [PDF]
, 2017 Preceding studies of persuasive technology have mentioned several benefits on the implementation of persuasive design features of the Persuasive System Design (PSD) model such as creating users' engagement and acceptance and continuous usage.
Shafin, Noor Afifah
core
COPD and cardiovascular disease [PDF]
, 2019 COPD is one of the major public health problems in people aged 40 years or above. It is currently the 4th leading cause of death in the world and projected to be the 3rd leading cause of death by 2020.
André, S. +5 more
core +3 more sources
Advanced Sensor Research, EarlyView.This study provides the first detailed comparison of the mechanisms behind differential pulse voltammetry and electrochemical impedance spectroscopy in electropolymerized molecularly imprinted polymer (MIP) sensing platforms. Using cystatin C as a model protein, it reveals how electron transfer processes generate signals and offers evidence‐based ...
Meriem Kassar +6 more
wiley +1 more source
Dynamic Studies Of Truncated Troponin Complex Usin Hdx [PDF]
Biophysical Journal, 2009 Troponin is the primary control protein of the cardiac and skeletal muscle contractile apparatus. Troponin is made up of three subunits (TnT, TnI, TnC) and is located on the thin filament together with tropomyosin. The binding of Ca++ to TnC induces conformational changes in troponin leading to muscle contraction, via a regulatory mechanism that ...
Larry S. Tobacman, Dev Kowlessur
openaire +2 more sources
, 1995 Quasi-elastic light scattering (QELS) is applied to investigate the effect of the tropomyosin/troponin complex (Tm/Tn) on the stiffness of actin filaments. The importance of hydrodynamic screening in semidilute solutions is demonstrated.
Baermann, M. +4 more
core +1 more source
Amino Acid Changes at Arginine 204 of Troponin I Result in Increased Calcium Sensitivity of Force Development. [PDF]
, 2016 Mutations in human cardiac troponin I (cTnI) have been associated with restrictive, dilated, and hypertrophic cardiomyopathies. The most commonly occurring residue on cTnI associated with familial hypertrophic cardiomyopathy (FHC) is arginine (R), which ...
Cui, Ziyou +4 more
core +2 more sources
Injectable BMSC‐Based Extracellular Matrix‐Mimicking Microtissue for Myocardial Infarction Repair
Advanced Science, EarlyView.A novel injectable biomimetic extracellular matrix scaffold (JLSV) is designed for enhanced delivery of bone marrow‐derived mesenchymal stem cells (BMSCs). By utilizing janus basic nanotubes, laminin, stromal‐derived factor‐1 alpha, and vascular endothelial growth factor, this innovative JLSV–BMSC microtissue shows promise in myocardial infarction ...
Lina Yao +7 more
wiley +1 more source
The Journal of Clinical InvestigationDilated cardiomyopathy (DCM) due to genetic disorders results in decreased myocardial contractility, leading to high morbidity and mortality rates. There are several therapeutic challenges in treating DCM, including poor understanding of the underlying ...
Ping Wang +25 more
doaj +1 more source