Impact of genotype and phenotype on cardiac biomarkers in patients with transthyretin amyloidosis - Report from the Transthyretin Amyloidosis Outcome Survey (THAOS). [PDF]
AIM:Cardiac troponins and natriuretic peptides are established for risk stratification in light-chain amyloidosis. Data on cardiac biomarkers in transthyretin amyloidosis (ATTR) are lacking.
Arnt V Kristen+6 more
doaj +11 more sources
Avaliação dos valores séricos de troponina I cardíaca em crianças menores de 1 ano de idade Evaluation of serum cardiac troponin I values in children less than 1 year of age [PDF]
OBJETIVO: Verificar os valores séricos para troponina I cardíaca em crianças abaixo de um ano de idade, sem disfunção cardíaca clínica. MÉTODOS: Os níveis séricos de troponina I cardíaca foram determinados em 99 crianças com idade abaixo de um ano ...
Antonio Carlos Arruda Souto+1 more
doaj +2 more sources
Hydrodynamic properties of bovine cardiac troponin-I and troponin-T.
Bovine cardiac troponin-I (TN-I) and troponin-T (TN-T) have been examined in solution using ultracentrifugation, gel filtration, and viscosity. A new method of purifying TN-T, employing hydroxylapatite chromatography in 6 M urea, is reported. Cardiac TN-T (Mr = 36,000) undergoes a reversible, concentration-dependent association in nondenaturing buffers,
David M. Byers, C.M. Kay
openalex +4 more sources
Clinical Utility of Cardiac Troponin I and Cardiac Troponin T Measurements [PDF]
The measurement of CK-MB remains the test of choice for confirmation or exclusion of AMI and probably will remain the test of choice for routine diagnosis in the near future.
Michaela Adamcová+2 more
doaj +3 more sources
Half-Life and Clearance of Cardiac Troponin I and Troponin T in Humans. [PDF]
BACKGROUND: Cardiac troponin (cTn) is key in diagnosing myocardial infarction (MI). After MI, the clinically observed half-life of cTn has been reported to be 7 to 20 hours, but this estimate reflects the combined elimination and simultaneous release of cTn from cardiomyocytes.
Kristensen JH+22 more
europepmc +5 more sources
Dephosphorylation specificities of protein phosphatase for cardiac troponin I, troponin T, and sites within troponin T [PDF]
Protein dephosphorylation by protein phosphatase 1 (PP1), acting in concert with protein kinase C (PKC) and protein kinase A (PKA), is a pivotal regulatory mechanism of protein phosphorylation.
Brian H Crawford+3 more
doaj +4 more sources
Hypertensive crisis can present with cardiac troponin elevation and unobstructed coronary arteries. We used cardiac magnetic resonance (CMR) imaging to characterize the myocardial tissue in patients with hypertensive crisis, elevated cardiac troponin ...
Mohammed A. Talle+4 more
doaj +1 more source
IMPORTANCE:. Troponin I is frequently elevated in sepsis, but optimal clinical approaches to diagnosis and management of troponin I during sepsis are unclear. OBJECTIVES:.
Michael A. Garcia, MD+3 more
doaj +1 more source
Renal Elimination of Troponin T and Troponin I [PDF]
Cardiovascular complications represent the predominant cause of death in patients in the terminal stage of renal failure. Increased concentrations of cardiac troponin T (cTnT) may be a valuable predictor of cardiac risk (1)(2). However, cardiac troponin I (cTnI), clinical symptoms, and electrocardiogram (ECG) indications may be absent in patients with ...
Andreas Lun+10 more
openaire +3 more sources
The Prognostic Significance of Troponin I and Troponin T [PDF]
Abstract. Objectives: To determine and compare the prognostic abilities of early, single‐sample measurements of cardiac troponin I (cTn‐I), cardiac troponin T (cTn‐T), creatine kinase‐MB (CK‐MB) among ED patients with possible myocardial ischemia. Methods: Prospective collection of clinical and serologic data using an identity‐unlinked technique from
Edward S. Bessman+5 more
openaire +3 more sources