Troponin I – a comprehensive review of its function, structure, evolution, and role in muscle diseases [PDF]
The troponin complex is a critical component of thin filaments and plays an essential role in the calcium-mediated regulation of contraction and relaxation in striated muscles, including both cardiac and skeletal muscle.
Dongju Han+3 more
doaj +2 more sources
The prognostic value of postoperative cardiac troponin I and T for major adverse cardiac events after coronary artery bypass grafting: a systematic review [PDF]
Background: This systematic review describes the prognostic value of postoperative cardiac high-sensitive troponin I and T as risk markers for major adverse cardiac events (MACE) after coronary artery bypass graft (CABG) surgery and their predictive ...
Maaike S.Y. Thio+7 more
doaj +2 more sources
Hydrodynamic properties of bovine cardiac troponin-I and troponin-T.
Bovine cardiac troponin-I (TN-I) and troponin-T (TN-T) have been examined in solution using ultracentrifugation, gel filtration, and viscosity. A new method of purifying TN-T, employing hydroxylapatite chromatography in 6 M urea, is reported. Cardiac TN-T (Mr = 36,000) undergoes a reversible, concentration-dependent association in nondenaturing buffers,
David M. Byers, C.M. Kay
openalex +4 more sources
Cardiac Troponin T and Troponin I in the General Population [PDF]
Supplemental Digital Content is available in the text.
P. Welsh+14 more
semanticscholar +6 more sources
Impact of genotype and phenotype on cardiac biomarkers in patients with transthyretin amyloidosis - Report from the Transthyretin Amyloidosis Outcome Survey (THAOS). [PDF]
AIM:Cardiac troponins and natriuretic peptides are established for risk stratification in light-chain amyloidosis. Data on cardiac biomarkers in transthyretin amyloidosis (ATTR) are lacking.
Arnt V Kristen+6 more
doaj +6 more sources
Clinical Utility of Cardiac Troponin I and Cardiac Troponin T Measurements [PDF]
The measurement of CK-MB remains the test of choice for confirmation or exclusion of AMI and probably will remain the test of choice for routine diagnosis in the near future.
Michaela Adamcová+2 more
doaj +3 more sources
Background The association of troponin-I levels and outcome in medical-surgical ICU patients has been studied before in populations with low to moderate prevalence of cardiovascular risk factors.
Abdulaleem Alatassi+5 more
doaj +2 more sources
Dephosphorylation specificities of protein phosphatase for cardiac troponin I, troponin T, and sites within troponin T [PDF]
Protein dephosphorylation by protein phosphatase 1 (PP1), acting in concert with protein kinase C (PKC) and protein kinase A (PKA), is a pivotal regulatory mechanism of protein phosphorylation.
Brian H Crawford+3 more
doaj +4 more sources
High incidence of macrotroponin I with a high-sensitivity troponin I assay [PDF]
Cardiac troponin is the preferred biomarker of myocardial injury. High-sensitivity troponin assays allow measurement of very low levels of troponin with excellent precision.
J. Warner, G. Marshall
semanticscholar +3 more sources
High-Sensitivity Troponin I after Cardiac Surgery and 30-Day Mortality.
BACKGROUND Consensus recommendations regarding the threshold levels of cardiac troponin elevations for the definition of perioperative myocardial infarction and clinically important periprocedural myocardial injury in patients undergoing cardiac surgery ...
P. Devereaux+48 more
semanticscholar +1 more source