Results 31 to 40 of about 153,000 (334)

Interaction of bepridil with the cardiac troponin C/troponin I complex [PDF]

FEBS Letters, 2001
We have investigated the binding of bepridil to calcium‐saturated cardiac troponin C in a cardiac troponin C/troponin I complex. Nuclear magnetic resonance spectroscopy and [15N,2H]cardiac troponin C permitted the mapping of bepridil‐induced amide proton chemical shifts. A single bepridil‐binding site in the regulatory domain was found with an affinity
Ekram Abusamhadneh, Alex Dvoretsky, Paul R. Rosevear, Natosha Finley, Soumya Sasi, M. Bret Abbott   +5 more
openaire   +3 more sources

A study on elevation of troponin I in ischemic stroke as an independent prognostic marker of outcomes

Nepal Journal of Neuroscience, 2020
Background: Stroke is the second leading cause of death worldwide, comprising approximately 10% of all deaths. A substantial number of stroke patients have elevated cardiac troponin levels and are associated with poorer prognosis.
Pradeep Thapa, Jagdish Prasad Agrawal, Rajani Baniya   +2 more
doaj   +1 more source

Cardiac troponin I as compared to troponin T for the detection of myocardial damage in horses [PDF]

, 2015
Background: Different cardiac troponin I (cTnI) assays give different results. Only 1 manufacturer has marketed troponin T (cTnT) assays. Therefore, cTnT often is preferred for detection of myocardial infarction in human patients.
De Clercq, Dominique, Decloedt, Annelies, Van Der Vekens, Nicky, van Loon, Gunther, Ven, Sofie   +4 more
core   +1 more source

Measurement of Calcium Dissociation Rates from Troponin C in Rigor Skeletal Myofibrils

Frontiers in Physiology, 2011
Ca2+ dissociation from the regulatory domain of troponin C may influence the rate of striated muscle relaxation. However, Ca2+ dissociation from troponin C has not been measured within the geometric and stoichiometric constraints of the muscle fiber ...
Sean C Little, Svetlana B Tikunova, Darl R. Swartz, Catalina eNorman, Jonathan P Davis   +4 more
doaj   +1 more source

Distinct conformational and functional effects of two adjacent pathogenic mutations in cardiac troponin I at the interface with troponin T

FEBS Open Bio, 2015
The α‐helix in troponin I (TnI) at the interface with troponin T (TnT) is a highly conserved structure. A point mutation in this region, A116G, was found in human cardiac TnI in a case of cardiomyopathy.
Shirin Akhter, J.-P. Jin
doaj   +1 more source

HUBUNGAN KADAR GLUKOSA DARAH PUASA DENGAN TROPONIN I PADA PASIEN INFARK MIOKARD AKUT

An-Nadaa: Jurnal Kesehatan Masyarakat, 2022
Infark miokard akut (IMA) merupakan penyebab kematian tertinggi di dunia akibat terbentuk plak aterosklerotik, sehingga menyebabkan iskemia miokard. Hal ini memicu terjadinya nekrosis sel miokard yang menyebabkan gangguan sarkolema, sehingga terjadi ...
Ledy Oktabelia, Debie Anggraini, haves ashan   +2 more
doaj   +1 more source

Troponin T and troponin I at acut coronary sendrom

Turkish Bulletin of Hygiene and Experimental Biology, 2011
Objective: Troponins and tropomyosins are not only the structural proteins that play roles in arrangement of skeletal and heart muscles, but also sensitive and spesific markers of heart muscle damage. In this study we aimed to compare the values of sensitivity, specifity, positive and negative predictive values of troponin T and troponin I which were ...
Canan Topcuoglu, Mehmet Avcikucuk, Ali Guctekin, Fatih Bakir   +3 more
openaire   +2 more sources

Prognostic value of troponin I after coronary artery bypass grafting (AMIRI-CABG study)

Вестник трансплантологии и искусственных органов, 2021
In 2017, the European Society of Cardiology outlined the importance of the problem of diagnosing myocardial ischemia-reperfusion injury following coronary artery bypass grafting.
N. S. Bunenkov, V. V. Komok, S. A. Bely, A. V. Sokolov, V. I. Lukashenko, A. S. Nemkov, G. G. Khubulava   +6 more
doaj   +1 more source

Type 2 myocardial infarction: the chimaera of cardiology? [PDF]

, 2015
The term type 2 myocardial infarction first appeared as part of the universal definition of myocardial infarction. It was introduced to cover a group of patients who had elevation of cardiac troponin but did not meet the traditional criteria for acute ...
[No authors listed], [No authors listed], Ammann, Apple, Assomull, Babuin, Bakshi, Baron, Bonaca, Botto, Collinson, Collinson, Collinson, Collinson, Cummins, Cummins, Davies, Davies, Falk, Gerhardt, Guest, Hamm, Javed, Jesse, Katus, Keller, Kollef, Latini, Lindahl, Melanson, Melberg, Morrow, Ohman, Ostermann, Ravkilde, Reichlin, Saaby, Saaby, Sandoval, Smith, Stein, Stubbs, Szymanski, Thygesen, Thygesen, Thygesen, Wu   +46 more
core   +1 more source

Cardiac troponin i in acute pericarditis [PDF]

Journal of the American College of Cardiology, 2003
This study was designed to investigate the prognostic value of cardiac troponin I (cTnI) in viral or idiopathic pericarditis.Idiopathic acute pericarditis has been recently reported as a possible cause of nonischemic release of cTnI. The prognostic value of this observation remains unknown.We enrolled 118 consecutive cases (age 49.2 +/- 18.4 years; 61 ...
Imazio, Massimo, Demichelis, Brunella, Cecchi, Enrico, Belli, Riccardo, Ghisio, Aldo, Bobbio, Marco, Trinchero, Rita   +6 more
openaire   +3 more sources