Measurement of Calcium Dissociation Rates from Troponin C in Rigor Skeletal Myofibrils
Ca2+ dissociation from the regulatory domain of troponin C may influence the rate of striated muscle relaxation. However, Ca2+ dissociation from troponin C has not been measured within the geometric and stoichiometric constraints of the muscle fiber ...
Sean C Little +4 more
doaj +1 more source
Background: While troponin is an established biomarker of cardiac injury, its prognostic significance in post-cardiotomy cardiogenic shock patients supported by venoarterial extracorporeal membrane oxygenation (PCCS–VA-ECMO) remains unclear.
Małgorzata Celińska-Spodar +6 more
doaj +1 more source
Troponins, Acute Coronary Syndrome and Renal Disease: From Acute Kidney Injury Through End-stage Kidney Disease [PDF]
The diagnosis of acute coronary syndromes (ACS) is heavily dependent on cardiac biomarker assays, particularly cardiac troponins. ACS, particularly non-ST segment elevation MI, are more common in patients with acute kidney injury, chronic kidney disease (
Banerjee, A, Banerjee, D, Ferrett, C
core +2 more sources
Prognostic importance of emerging cardiac, inflammatory, and renal biomarkers in chronic heart failure patients with reduced ejection fraction and anaemia: RED-HF study [PDF]
Aims: To test the prognostic value of emerging biomarkers in the Reduction of Events by Darbepoetin Alfa in Heart Failure (RED-HF) trial. Methods and results: Circulating cardiac [N-terminal pro-B-type natriuretic peptide (NT-proBNP), and high ...
Alehagen +34 more
core +4 more sources
Cardiac Troponin I Gene Knockout [PDF]
Abstract —Troponin I is a subunit of the thin filament–associated troponin-tropomyosin complex involved in calcium regulation of skeletal and cardiac muscle contraction. We deleted the cardiac isoform of troponin I by using gene targeting in murine embryonic stem cells to determine the developmental and physiological effects of
X, Huang +6 more
openaire +2 more sources
Urine high–sensitive troponin I in children cannot offer an applicable alternative to serum
IntroductionIn children, congenital heart defects represent the primary cause of increased serum troponin I. The elimination process of cardiac troponin I from the bloodstream and the factors influencing this process remain unknown. The objective of this
Matija Bakoš +15 more
doaj +1 more source
HUBUNGAN KADAR GLUKOSA DARAH PUASA DENGAN TROPONIN I PADA PASIEN INFARK MIOKARD AKUT
Infark miokard akut (IMA) merupakan penyebab kematian tertinggi di dunia akibat terbentuk plak aterosklerotik, sehingga menyebabkan iskemia miokard. Hal ini memicu terjadinya nekrosis sel miokard yang menyebabkan gangguan sarkolema, sehingga terjadi ...
Ledy Oktabelia +2 more
doaj +1 more source
The 99th percentile of reference population for cTnI and cTnT assay: Methodology, pathophysiology and clinical implications [PDF]
According to recent international guidelines, including the 2012 Third Universal Definiton of Myocardial Infarction by the Joint ESC/ACCF/AHA/WHF Task Force, an increase in cardiac troponin (cTn) levels over the 99th percentile upper reference limit ...
Clerico, Aldo +6 more
core +1 more source
Predictors of cardiac troponin release after a marathon [PDF]
Objectives: Exercise leads to an increase in cardiac troponin I in healthy, asymptomatic athletes after a marathon. Previous studies revealed single factors to relate to post-race cardiac troponin I levels.
Eijsvogels, TM +6 more
core +1 more source
Prognostic value of troponin I after coronary artery bypass grafting (AMIRI-CABG study)
In 2017, the European Society of Cardiology outlined the importance of the problem of diagnosing myocardial ischemia-reperfusion injury following coronary artery bypass grafting.
N. S. Bunenkov +6 more
doaj +1 more source

