Results 41 to 50 of about 153,000 (334)

A Revised Perspective on the Evolution of Troponin I and Troponin T Gene Families in Vertebrates

open access: yesGenome Biology and Evolution, 2022
Abstract The troponin (Tn) complex, responsible for the Ca2+ activation of striated muscle, is composed of three interacting protein subunits: TnC, TnI, and TnT, encoded by TNNC, TNNI, and TNNT genes. TNNI and TNNT are sister gene families, and in mammals the three TNNI paralogs (TNNI1, TNNI2, TNNI3), which encode proteins with tissue ...
William Joyce   +5 more
openaire   +3 more sources

Urine high–sensitive troponin I in children cannot offer an applicable alternative to serum

open access: yesFrontiers in Cardiovascular Medicine
IntroductionIn children, congenital heart defects represent the primary cause of increased serum troponin I. The elimination process of cardiac troponin I from the bloodstream and the factors influencing this process remain unknown. The objective of this
Matija Bakoš   +15 more
doaj   +1 more source

Troponin T or troponin I as cardiac markers in ischaemic heart disease [PDF]

open access: yesHeart, 2000
There is increasing awareness of the limitations of standard biochemical markers of cardiac damage in patients with acute coronary syndromes. A desire to improve sensitivity and specificity has led to the search for markers uniquely expressed by the myocardium.
Aaj Adgey   +2 more
openaire   +2 more sources

Negative Troponin I as a Predictor of Survival in Patients With Coronavirus Disease 2019

open access: yesInternational Journal of Cardiology: Heart & Vasculature, 2023
Background: Despite a large amount of evidence evaluating elevated troponin I levels and adverse clinical outcomes, little is known about the role of a normal (negative) troponin I during the first 24 h of admission for risk stratification in patients ...
Fergie J. Losiniecki   +7 more
doaj  

Troponin-I release after cardiac surgery with different surgical techniques and post-operative neurological outcomes

open access: yesMcGill Journal of Medicine, 2020
Cerebral hypoperfusion during cardiopulmonary bypass surgery has been thought to be a factor in the aetiology of brain damage with evidence of post operative neurological deficits.
Nozeihan Jan Bappu   +3 more
doaj   +1 more source

Inverted Takotsubo Syndrome With HELLP Syndrome: A Case Report

open access: yesFrontiers in Cardiovascular Medicine, 2022
BackgroundTakotsubo syndrome is an acute cardiac condition involving sudden, transient apical ballooning of the left ventricle of the heart that may be triggered by emotional stress and some non-cardiac conditions.
Paul Gabarre   +15 more
doaj   +1 more source

Investigating the role of uncoupling of troponin I phosphorylation from changes in myofibrillar Ca(2+)-sensitivity in the pathogenesis of cardiomyopathy. [PDF]

open access: yes, 2014
Contraction in the mammalian heart is controlled by the intracellular Ca2+ concentration as it is in all striated muscle, but the heart has an additional signalling system that comes into play to increase heart rate and cardiac output during exercise or ...
Marston, SB, Messer, AE
core   +2 more sources

Interaction of Cardiac Troponin C and Troponin I with W7 in the Presence of Three Functional Regions of Cardiac Troponin I [PDF]

open access: yesBiochemistry, 2006
W7 is a well-known calmodulin (CaM) antagonist and has been implicated as an inhibitor of the troponin C-mediated Ca(2+) activation of cardiac muscle contraction. In this study, we use NMR spectroscopy to study binding of W7 to cardiac troponin C (cTnC) free or in complex with cardiac troponin I (cTnI) peptides.
Ryan M. B. Hoffman   +2 more
openaire   +2 more sources

High-sensitivity Troponin I Assay for Early Detection of Myocardial Injury in Carbon Monoxide Intoxication

open access: yesJournal of Medical Sciences
Background: Carbon monoxide (CO) intoxication is the most common gas-related event resulting in emergency room (ER) visits, often leading to myocardial injuries measured through the assessment of troponin levels. Recent efforts have focused on developing
Tsung-Neng Tsai   +5 more
doaj   +1 more source

Troponin I and cardiovascular risk prediction in the general population: the BiomarCaRE consortium [PDF]

open access: yes, 2016
Our aims were to evaluate the distribution of troponin I concentrations in population cohorts across Europe, to characterize the association with cardiovascular outcomes, to determine the predictive value beyond the variables used in the ESC SCORE, to ...
BiomarCaRE Investigators ()   +27 more
core   +2 more sources

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