Results 41 to 50 of about 153,000 (334)

A Revised Perspective on the Evolution of Troponin I and Troponin T Gene Families in Vertebrates

Genome Biology and Evolution, 2022
Abstract The troponin (Tn) complex, responsible for the Ca2+ activation of striated muscle, is composed of three interacting protein subunits: TnC, TnI, and TnT, encoded by TNNC, TNNI, and TNNT genes. TNNI and TNNT are sister gene families, and in mammals the three TNNI paralogs (TNNI1, TNNI2, TNNI3), which encode proteins with tissue ...
William Joyce, Daniel M Ripley, Todd Gillis, Amanda Coward Black, Holly A Shiels, Federico G Hoffmann   +5 more
openaire   +3 more sources

Urine high–sensitive troponin I in children cannot offer an applicable alternative to serum

Frontiers in Cardiovascular Medicine
IntroductionIn children, congenital heart defects represent the primary cause of increased serum troponin I. The elimination process of cardiac troponin I from the bloodstream and the factors influencing this process remain unknown. The objective of this
Matija Bakoš, Daniel Dilber, Daniel Dilber, Anamarija Jazbec, Anamarija Jazbec, Tomo Svaguša, Ana-Meyra Potkonjak, Duje Braovac, Željko Đurić, Andrea Radeljak, Ana Lončar Vrančić, Hrvoje Vraneš, Slobodan Galić, Milivoj Novak, Ingrid Prkacin, Ingrid Prkacin   +15 more
doaj   +1 more source

Troponin T or troponin I as cardiac markers in ischaemic heart disease [PDF]

Heart, 2000
There is increasing awareness of the limitations of standard biochemical markers of cardiac damage in patients with acute coronary syndromes. A desire to improve sensitivity and specificity has led to the search for markers uniquely expressed by the myocardium.
Aaj Adgey, Ian Menown, Suzanne J. Maynard   +2 more
openaire   +2 more sources

Negative Troponin I as a Predictor of Survival in Patients With Coronavirus Disease 2019

International Journal of Cardiology: Heart & Vasculature, 2023
Background: Despite a large amount of evidence evaluating elevated troponin I levels and adverse clinical outcomes, little is known about the role of a normal (negative) troponin I during the first 24 h of admission for risk stratification in patients ...
Fergie J. Losiniecki, Jose Lopez, Majd Jazaerly, Kristina Menchaca, Vivek Kothari, Brendon Cornett, Christopher N. Ochner, Robert Chait   +7 more
doaj  

Troponin-I release after cardiac surgery with different surgical techniques and post-operative neurological outcomes

McGill Journal of Medicine, 2020
Cerebral hypoperfusion during cardiopulmonary bypass surgery has been thought to be a factor in the aetiology of brain damage with evidence of post operative neurological deficits.
Nozeihan Jan Bappu, Panangipalli Venugopal, Akhshay Kumar Bisoi, Pankaj S Mankad   +3 more
doaj   +1 more source

Inverted Takotsubo Syndrome With HELLP Syndrome: A Case Report

Frontiers in Cardiovascular Medicine, 2022
BackgroundTakotsubo syndrome is an acute cardiac condition involving sudden, transient apical ballooning of the left ventricle of the heart that may be triggered by emotional stress and some non-cardiac conditions.
Paul Gabarre, Pablo Ruiz, Camille Chenevier-Gobeaux, Etienne Charpentier, Laurie Soulat-Dufour, Laurie Soulat-Dufour, Ariel Cohen, Ariel Cohen, Laurence Monnier-Cholley, Lotfi Chemali, Hélène François, Hélène François, Mathieu Kerneis, Guillaume Lefèvre, Mathieu Boissan, Mathieu Boissan   +15 more
doaj   +1 more source

Investigating the role of uncoupling of troponin I phosphorylation from changes in myofibrillar Ca(2+)-sensitivity in the pathogenesis of cardiomyopathy. [PDF]

, 2014
Contraction in the mammalian heart is controlled by the intracellular Ca2+ concentration as it is in all striated muscle, but the heart has an additional signalling system that comes into play to increase heart rate and cardiac output during exercise or ...
Marston, SB, Messer, AE
core   +2 more sources

Interaction of Cardiac Troponin C and Troponin I with W7 in the Presence of Three Functional Regions of Cardiac Troponin I [PDF]

Biochemistry, 2006
W7 is a well-known calmodulin (CaM) antagonist and has been implicated as an inhibitor of the troponin C-mediated Ca(2+) activation of cardiac muscle contraction. In this study, we use NMR spectroscopy to study binding of W7 to cardiac troponin C (cTnC) free or in complex with cardiac troponin I (cTnI) peptides.
Ryan M. B. Hoffman, Monica X. Li, Brian D. Sykes   +2 more
openaire   +2 more sources

High-sensitivity Troponin I Assay for Early Detection of Myocardial Injury in Carbon Monoxide Intoxication

Journal of Medical Sciences
Background: Carbon monoxide (CO) intoxication is the most common gas-related event resulting in emergency room (ER) visits, often leading to myocardial injuries measured through the assessment of troponin levels. Recent efforts have focused on developing
Tsung-Neng Tsai, Chih-Hao Shen, Gen-Min Lin, Pang-Yen Liu, Ming-Yueh Liu, Li-Yen Huang   +5 more
doaj   +1 more source

Troponin I and cardiovascular risk prediction in the general population: the BiomarCaRE consortium [PDF]

, 2016
Our aims were to evaluate the distribution of troponin I concentrations in population cohorts across Europe, to characterize the association with cardiovascular outcomes, to determine the predictive value beyond the variables used in the ESC SCORE, to ...
BiomarCaRE Investigators (), Blankenberg, S., Brambilla, P., Costanzo, S., Everett, B.M., Iacoviello, L., Jørgensen, T., Kee, F., Koenig, W., Kontto, J., Kuulasmaa, K., Lackner, K.J., Linden, G.J., Makarova, N., Nauck, M., Ojeda, F., Patterson, C.C., Peters, A., Petersmann, A., Ridker, P.M., Salomaa, V., Schnabel, R.B., Thorand, B., Vartiainen, E., Veronesi, G., Wild, P., Yarnell, J., Zeller, T.   +27 more
core   +2 more sources