Results 121 to 130 of about 161,005 (352)
AGING MEDICINE, EarlyView.We generated genetically stable iPSCs from HGPS patients using a nonintegrative Sendai virus method. This approach preserves cellular integrity, enhances disease modeling, and enables accurate study of Progerin‐induced cardiovascular dysfunction. Overall, it provides a reliable platform for understanding HGPS and aging‐related disease pathology and ...
Juned Kadiwala, Rameen Shakur
wiley +1 more source
Troponins in Renal Dysfunction [PDF]
The International Journal of Artificial Organs, 2000 “I have yet to see any problem, however complicated, which, when you looked at it in the right way, did not become still more complicated.” Poul (William) Anderson
openaire +3 more sources
Impact of soluble fms-like tyrosine kinase-1 and placental growth factor serum levels for risk stratification and early diagnosis in patients with suspected acute myocardial infarction [PDF]
, 2017 Aims Angiogenic factors play an important role in the development of atherosclerosis and show pronounced changes during acute myocardial infarction (AMI). We analysed the impact of placental growth factor (PlGF) and its endogen opponent, soluble fms-like
Breidthardt, Tobias +11 more
core
Aggregate, EarlyView.Molecular confinement via polymer network allows for significant emission enhancement (80‐fold) of AIEgen with the exceptional quantum yield of 91%, and ultra‐stable photobleaching after continuous irradiation. Subsequently, by adjusting the filter bandwidth, remarkable signal amplification (2–10 folds) is achieved, and the sensitive detection was ...
Yaxin Hu +6 more
wiley +1 more source
The implementation of persuasive technology principles in mobile application development: a qualitative study [PDF]
, 2017 Preceding studies of persuasive technology have mentioned several benefits on the implementation of persuasive design features of the Persuasive System Design (PSD) model such as creating users' engagement and acceptance and continuous usage.
Shafin, Noor Afifah
core
Randomised controlled trial and economic evaluation of a chest pain observation unit compared with routine care [PDF]
, 2004 Objectives To measure the effectiveness and cost effectiveness of providing care in a chest pain observation unit compared with routine care for patients with acute, undifferentiated chest pain.
Angelini, K. +11 more
core +2 more sources
American Journal of Medical Genetics Part A, EarlyView.ABSTRACT Costello syndrome (CS) is a rare dominant HRAS RASopathy characterized by curly hair, cardiac abnormalities, craniofacial anomalies, and developmental delay. HRAS codon 58, 59, and 60 variants are associated with milder phenotypes. We describe a three‐generation family with a previously unreported heterozygous HRAS variant c.175G>A (p.Ala59Thr)
Nikole Rautiainen +10 more
wiley +1 more source
Annals of Neurology, EarlyView.Objective Tofersen is the first effective and approved therapy for superoxide dismutase 1 (SOD1)‐associated amyotrophic lateral sclerosis (ALS [SOD1‐ALS]). Following treatment with tofersen, neurofilament levels in patients' cerebrospinal fluid (CSF) and serum seem to respond earlier than clinical parameters.
Christina Steffke +36 more
wiley +1 more source
Annals of Neurology, EarlyView.Objective Biomarkers with clear contexts of use are important tools for amyotrophic lateral sclerosis (ALS) therapy development. Understanding their longitudinal trajectory in the untreated state is key to their use as potential markers of pharmacodynamic response.
Oleksandr Dergai +16 more
wiley +1 more source
مجله دانشگاه علوم پزشکی گرگان, 2014 Background and Objective: Cardiovascular diseases are the most frequent cause of death among hemodialysis patients. Left ventricular hypertrophy and systolic dysfunction are potent predictors of cardiovascular morbidity and mortality in hemodialysis ...
Sedighi O, Golshani S, Nikzad F
doaj