Results 121 to 130 of about 12,260,572 (400)

Troponin T Gene Switching Is Developmentally Regulated by Plasma-Borne Factors in Parabiotic Chicks [PDF]

open access: yes, 1996
Myogenesis involves a conserved program of muscle gene isoform switching requiring the synchronized induction and repression of numerous muscle-specific gene family members. Central to understanding the regulation of this process are questions related to
Ordahl, Charles P., Wong, Ted S.
core   +1 more source

Mitigating Doxorubicin‐Induced Cardiotoxicity and Enhancing Anti‐Tumor Efficacy with a Metformin‐Integrated Self‐Assembled Nanomedicine

open access: yesAdvanced Science, EarlyView.
A novel self‐assembled nanomedicine (PMDDH) has been developed for the co‐delivery of doxorubicin and metformin, aiming to enhance the anti‐tumor efficacy of doxorubicin while alleviating its cardiotoxicity through the activation of cGAS‐STING and AMPK signaling pathways, respectively.
Jiaxin Huang   +9 more
wiley   +1 more source

Diagnostic Value of Troponin I and T to Predict Mortality in Patients Undergoing Hemodialysis

open access: yesArchives of Anesthesia and Critical Care, 2018
Background: There is no known biomarker to predict the mortality risk in patients undergoing dialysis in the intensive care unit (ICU). Therefore, the current study aimed to determine the diagnostic value of troponin I and T in this respect.
Seyed Taghi Hashemi   +2 more
doaj  

Cardiac troponin T quantitative assay failure as a result of antibody interference

open access: yesAfrican Journal of Laboratory Medicine, 2013
Background: Immunoassays are prone to interference by various substances which may cause inaccurate results. This type of interference is difficult to detect analytically.
Philip H. Fortgens, Fierdoz Omar
doaj   +1 more source

Etiology, risk factors, and prognosis of patients with syncope: A single‐center analysis

open access: yesAnnals of Noninvasive Electrocardiology, 2021
Objective To investigate the main causes, risk factors, and prognosis of patients hospitalized with syncope. Methods The patients admitted due to syncope were included.
Lin Ling   +3 more
doaj   +1 more source

Cloning and homologic analysis of Tpn I gene in silkworm Bombyx mori [PDF]

open access: yes, 2010
The troponin complex is composed of three subunits, Troponin C (the calcium sensor component) and Troponin T and I (structural proteins). Tpn C is encoded by multiple genes in insects, while the Tpn T and Tpn I proteins are encoded by single genes. Tpn I
Chen, K   +7 more
core   +2 more sources

Metal–Organic Frameworks: Unlocking New Frontiers in Cardiovascular Diagnosis and Therapy

open access: yesAdvanced Science, EarlyView.
Metal–organic frameworks (MOFs), are composed of metal ions and bridging organic ligands, are recognized as an excellent platform for host‐gust chemistry. Its rich structural composition, modifiable sites, and multilevel pore distribution can provide delivery and release of signaling molecules, probes, and therapeutic drugs, which exhibit great medical
Qilu Wu   +6 more
wiley   +1 more source

Erythrocyte transketolase activity, markers of cardiac dysfunction and the diagnosis of infantile beriberi. [PDF]

open access: yesPLoS Neglected Tropical Diseases, 2011
BackgroundInfantile beriberi is a potentially lethal manifestation of thiamin deficiency, associated with traditional post-partum maternal food avoidance, which persists in the Lao PDR (Laos).
Douangdao Soukaloun   +14 more
doaj   +1 more source

Prospective validation of a 1-hour algorithm to rule-out and rule-in acute myocardial infarction using a high-sensitivity cardiac troponin T assay

open access: yesCanadian Medical Association Journal, 2015
Background: We aimed to prospectively validate a novel 1-hour algorithm using high-sensitivity cardiac troponin T measurement for early rule-out and rule-in of acute myocardial infarction (MI).
T. Reichlin   +28 more
semanticscholar   +1 more source

Leucine‐Rich Repeat‐Containing G Protein‐Coupled Receptor 6 Ameliorates Pressure Overload‐Induced Cardiac Hypertrophy by Regulating Cardiomyocyte Metabolic Reprogramming

open access: yesAdvanced Science, EarlyView.
LGR6 overexpression ameliorates cardiac hypertrophy by regulating metabolic reprogramming through USP4‐PPARα pathway. Abstract Metabolic reprogramming is a pivotal mechanism in the pathogenesis of pathological cardiac hypertrophy. Leucine‐rich repeat‐containing G protein‐coupled receptor 6 (Lgr6) has emerged as a significant player in cardiovascular ...
Mengmeng Zhao   +7 more
wiley   +1 more source

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