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Interactions among Chymotryptic Troponin T Subfragments, Tropomyosin, Troponin I and Troponin C1
The Journal of Biochemistry, 1984The binding of various combinations of chymotryptic troponin T subfragments, troponin I and troponin C to tropomyosin, troponin C and troponin I was examined semiquantitatively by using affinity chromatography. The interaction between troponin T2 and troponin I intensified the interaction between troponin T2 (or troponin T) and tropomyosin.
Iwao Ohtsuki, Masaru Tanokura
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The binding sites of rabbit skeletal troponin-I on troponin-T
Canadian Journal of Biochemistry, 1980Various fragments derived from rabbit skeletal muscle troponin-T (Tn-T) by chemical and (or) proteolytic cleavage were mixed with whole troponin-I (Tn-I) and applied to a Sephadex G-75 gel filtration column in order to determine the binding site of Tn-I on Tn-T. This site of interaction was found to span two distinct regions of Tn-T.
Joyce R. Pearlstone, Lawrence B. Smillie
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Clinica Chimica Acta
Cardiac troponin (cTn) testing plays a crucial role in the diagnosis of cardiovascular diseases, particularly acute coronary syndrome (ACS), which includes acute myocardial infarction (AMI). However, conventional immunoassays may be subject to interference from autoantibodies, cross-reactivity, and biotin-related effects, compromising diagnostic ...
Yumeng Gao +7 more
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Cardiac troponin (cTn) testing plays a crucial role in the diagnosis of cardiovascular diseases, particularly acute coronary syndrome (ACS), which includes acute myocardial infarction (AMI). However, conventional immunoassays may be subject to interference from autoantibodies, cross-reactivity, and biotin-related effects, compromising diagnostic ...
Yumeng Gao +7 more
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The Twilight Zone of Troponins
Heart Lung <html_ent glyph="@amp;" ascii="&"/> Circulation, 2003Since its introduction into the clinical environment in the early nineties, the cardiac enzyme troponin has significantly changed the way we diagnose and manage acute coronary syndromes. Troponin I is a biochemical marker of myocardial injury with a high level of specificity and sensitivity.
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Troponins in children and neonates
Acta Paediatrica, 2003Cardiac troponin T and cardiac troponin I—the biochemical markers of myocardial injury—are characterized by high specificity and sensitivity in comparison with other markers used in the past. Conclusion: Troponins have been studied in a wide range of clinical settings.
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Machine learning for diagnosis of myocardial infarction using cardiac troponin concentrations
Nature Medicine, 2023Dimitrios Doudesis +2 more
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