Did the introduction of high-sensitivity Troponin T for the assessment of suspected acute coronary syndrome in Malta result in reduction of hospitalization time? A retrospective review [PDF]
, 2018 Aims: Troponins I and T are biomarkers used for diagnosing myocardial infarction. The recently developed high-sensitivity Troponin T assay can detect levels as low as 3 ng/L which gives the advantage of rapid diagnosis of acute coronary syndrome (ACS ...
Alwatari, Yahya +3 more
core
Correlation of Troponin Level (Troponin T, Troponin I) With PELOD-2 Score in Sepsis as a Predictive Factor of Mortality [PDF]
, 2019 BACKGROUND: Sepsis in children with cardiovascular involvement can increase mortality. Recently, many studies have been conducted to investigate troponin as an early marker of myocardial dysfunction, associated with pediatric sepsis score.
Dauhan, Aileen Clarissa +3 more
core +2 more sources
Troponin in Chagas disease [PDF]
Brazilian Journal of Infectious Diseases, 2003 Chagas disease is still a major tropical diseasein Latin America, affecting 16 to 18 million people.About 6 million people are infected with thecausative organism, Trypanosoma cruzi , in Brazil[1]. However, it often remains for decades in itsindeterminate form, symptomless, with tissue injuryin about 30% of the cases, which eventually willevolve to ...
Aras, Roque +6 more
openaire +6 more sources
Advanced Biology, EarlyView.Extracellular vesicles (EVs) play a dual role in diagnostics and therapeutics, offering innovative solutions for treating cancer, cardiovascular, neurodegenerative, and orthopedic diseases. This review highlights EVs’ potential to revolutionize personalized medicine through specific applications in disease detection and treatment.
Farbod Ebrahimi +4 more
wiley +1 more source
The value of troponin assays in modern medical practice [PDF]
, 2016 Cardiac troponins – C, I and T – form part of the troponin complex which is involved in the regulation of the calcium-mediated interaction of actin and myosin in myocytes. Each troponin has a different role in the above mentioned complex.
Cutajar, Karl
core
Cardiac troponin T estimation post elective stent implantation and prediction of early and late outcomes [PDF]
, 2017 Background: Coronary artery disease (CAD) is a major cause of mortality and morbidity. Per Cutaneous Interventions (PCI) is emerging as the mainstay of treatment for CAD.
K. K., Sarosh Kumar +2 more
core +2 more sources
Anti–Cardiac Troponin Autoantibodies Are Specific to the Conformational Epitopes Formed by Cardiac Troponin I and Troponin T in the Ternary Troponin Complex [PDF]
Clinical Chemistry, 2017 Abstract BACKGROUND Autoantibodies to cardiac troponins (TnAAbs) could negatively affect cardiac troponin I (cTnI) measurements by TnAAbs-sensitive immunoassays. We investigated the epitope specificity of TnAAbs and its influence on cTnI immunodetection in patients with acute myocardial infarction ...
Alexandra V Vylegzhanina +7 more
openaire +3 more sources
Advanced Functional Materials, EarlyView.In this work, melt electrowriting is used to fabricate a 3D printed scaffold design that generates engineered cardiac tissues with in‐plane contraction, mimicking natural myocardium. It is shown that these tissues display advanced maturation and functionality.
Olalla Iglesias‐García +23 more
wiley +1 more source
The side chain of glutamine 13 is the acyl-donor amino acid modified by type 2 transglutaminase in subunit T of the native rabbit skeletal muscle troponin complex. [PDF]
, 2013 Subunit T of the native muscle troponin complex is a recognised substrate of transglutaminase both in vitro and in situ with formation of isopeptide bonds.
B. Ura +9 more
core +1 more source