Results 61 to 70 of about 471,725 (296)

Response to Allopurinol and Febuxostat According to the Fractional Excretion of Urate in Men With Gout

Arthritis Care &Research, EarlyView.
Objective Body mass index (BMI), glomerular filtration rate (GFR), and pretreatment urate levels have been reported to influence the urate‐lowering response to allopurinol. We investigated whether the fractional excretion of uric acid (FEUA) also modulates this response and relates to oxypurinol concentrations.
Pascal Richette, Anouk Walter‐Petrich, Quang Dinh Nguyen, Matthieu Resche‐Rigon, Quang Huy Dinh Nguyen, Minh Duc Do, Thao Phuong Mai, Tuan Duc Nguyen, Fernando Perez‐Ruiz, Emmanuel Letavernier, Tristan Pascart, Augustin Latourte, Hang Korng Ea, Thomas Bardin   +13 more
wiley   +1 more source

Z-Tetraol Reflow in Heat-Assisted Magnetic Recording

Tribology Online, 2016
Lubricant reflow for Z-Tetraol is characterized for heat-assisted magnetic recording (HAMR). The thickness-dependent diffusion constant, D(h), is determined from flow experiments for submonolayer Z-Tetraol films between 2.5 and 13 Å.
Robert J. Waltman
doaj   +1 more source

Aminoglycoside trough levels in neonates [PDF]

Srpski Arhiv za Celokupno Lekarstvo, 2010
Introduction. Drug safety depends on trough levels. Objective. Objective of the study was to measure gentamicin and amikacin trough levels in neonates and to identify risk groups by gestational and postnatal age. Methods.
Pejović Biljana, Ranković-Janevski Milica, Božinović-Prekajski Niveska   +2 more
doaj   +1 more source

Multi-soliton Solutions of Two-dimensional Matrix Davey-Stewartson Equation [PDF]

, 1996
The explicit formulae for m-soliton solutions of (1+2)-dimensional matrix Davey-Stewartson equation are represented. They are found by means of known general solution of the matrix Toda chain with the fixed ends [1].
A.N. Leznov, Boiti, Bonora, Davey, E.A. Yuzbashyan, Fairlie, Gelfand, Gelfand, Leznov, Leznov, Leznov, Leznov, Leznov, Leznov, Leznov, Leznov   +15 more
core   +3 more sources

Pharmacokinetics, Pharmacodynamics, and Safety of Subcutaneous Belimumab in Pediatric Patients With Systemic Lupus Erythematosus: A Multicenter, Open‐Label Trial

Arthritis Care &Research, EarlyView.
Objective This study aimed to characterize the pharmacokinetics, pharmacodynamics, safety, and exploratory efficacy of subcutaneous belimumab in pediatric patients with active systemic lupus erythematosus (SLE) receiving standard therapy. Methods This single‐arm, multicenter, open‐label trial (GSK study 200908; ClinicalTrials.gov identifier ...
Hermine I. Brunner, Jordi Antón, Inmaculada Calvo‐Penadés, Richard Dimelow, Gerd Horneff, Sylvia Kamphuis, Rebecca Marino, Andre van Maurik, Kirsten Minden, Masaaki Mori, Josephine Ocran‐Appiah, Christel Wilkinson, Yuichi Yamasaki, Deepak Assudani, for the Pediatric Rheumatology Collaborative Study Group (PRCSG) and Paediatric Rheumatology International Trials Organisation (PRINTO) Network investigators   +14 more
wiley   +1 more source

The process of web wrinkle formation on a roller and its prevention with a curved axis roller (A web transfer simulation for roller tilt)

Nihon Kikai Gakkai ronbunshu
The process of a trough stepping into a wrinkle during web transfer is simulated by FEM commercial software. Two models are employed. The first one consists of a web and four cylindrical rollers, while the second one has a curved axis roller instead of a
Shigeo YANABE
doaj   +1 more source

Association between pazopanib exposure and safety in Japanese patients with renal cell carcinoma or soft tissue sarcoma

Scientific Reports, 2023
The safety and effectiveness of pazopanib are related to plasma trough concentrations in renal cell carcinoma (RCC); however, data on pazopanib plasma trough concentrations with soft tissue sarcoma (STS) are limited.
Takeshi Aoyama, Kenji Nakano, Takeshi Yuasa, Erika Sugiyama, Takako Okawa, Kazuyuki Ito, Keiichi Azuma, Koki Hashimoto, Ryota Furutani, Makoto Hiraide, Kazuo Kobayashi, Kenichi Suzuki, Jyunnichi Tomomatsu, Masataka Tajima, Hitoshi Sato, Toshihiro Hama, Shunji Takahashi   +16 more
doaj   +1 more source

Clinical Significance of Therapeutic Drug Level Monitoring for Mycophenolate in Patients With Extrarenal Systemic Lupus Erythematosus—A Systematic Review and Meta‐Analysis

Arthritis Care &Research, EarlyView.
Objective Clinical response to mycophenolic acid (MPA) is highly heterogeneous; thus, therapeutic drug level monitoring (TDM) may help improve treatment efficacy. This systematic review and meta‐analysis examined therapeutic ranges for MPA levels associated with better outcomes and safety in patients with systemic lupus erythematosus (SLE ...
Zahraa Qamhieh, Dalia Sriwi, Callie Saric, Tripti Singh, Christie M. Bartels, Shivani Garg   +5 more
wiley   +1 more source

Development and exploration practice of the concept of hydrocarbon accumulation in rifted-basin troughs: A case study of Paleogene Kongdian Formation in Cangdong sag, Bohai Bay Basin

Petroleum Exploration and Development, 2018
Based on the merged 3D seismic data, well logging, formation testing, analysis and testing data, the structural evolution, sedimentary reservoirs, thermal evolution of source rocks were investigated of Paleogene Kongdian Formation in the trough area of ...
Xianzheng ZHAO, Lihong ZHOU, Xiugang PU, Fengming JIN, Wenya JIANG, Dunqing XIAO, Wenzhong HAN, Zhannan SHI   +7 more
doaj   +1 more source

Real‐World Longitudinal Data on the Impact of Hydroxychloroquine Blood Level Monitoring on Lupus Outcomes: Results of a Prospective Longitudinal Cohort Study

Arthritis Care &Research, EarlyView.
Objective Hydroxychloroquine (HCQ) is a cornerstone therapy in systemic lupus erythematosus (SLE), but the weight‐based dosing does not account for clinical factors that can introduce individual variability in drug metabolism and clearance. We leveraged longitudinal data from a prospective SLE cohort to identify clinical factors that predict ...
Jay J. Patel, Fauzia Hollangel, Caroline Packee, Amita Kapoor, Brad Rovin, Nathalie Costedoat‐Chalumeau, Shivani Garg   +6 more
wiley   +1 more source