Results 51 to 60 of about 471,725 (296)

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

Numerical modeling of two-dimensional temperature dynamics across ice-wedge polygons [PDF]

, 2017
Thesis (M.S.) University of Alaska Fairbanks, 2017The ice wedges on the North Slope of Alaska have been forming for many millennia, when the ground cracked and the cracks were filled with snowmelt water.
Garayshin, Viacheslav Valer'evich, Гарайшин, Вячеслав Валерьевич   +1 more
core  

Flow and retreat of the Late Quaternary Pine Island-Thwaites palaeo-ice stream, West Antarctica [PDF]

, 2010
Multibeam swath bathymetry and sub-bottom profiler data are used to establish constraints on the flow and retreat history of a major palaeo-ice stream that carried the combined discharge from the parts of the West Antarctic Ice Sheet now occupied by the ...
Alastair G. C. Graham, Alley, Anandakrishnan, Anderson, Anderson, Canals, Clark, Claus-Dieter Hillenbrand, Conway, Domack, Dowdeswell, Dowdeswell, Dowdeswell, Dowdeswell, Evans, Evans, Gerhard Kuhn, Graham, Heroy, Holt, Hubbard, Hughes, Jacobs, James A. Smith, Jeffrey Evans, Julian A. Dowdeswell, Karsten Gohl, King, Larter, Larter, Lowe, Lowe, Mosola, Nitsche, Noormets, Nygård, Ottesen, Ottesen, Payne, Pritchard, Pudsey, Rignot, Rignot, Rignot, Rignot, Rignot, Robert D. Larter, Schoof, Scott, Sharpe, Shaw, Shepherd, Shepherd, Shipp, Shipp, Smith, Stokes, Stokes, Stokes, Tara Deen, Thoma, Vaughan, Vaughan, Vaughan, Vaughan, Walker, Weertman, Wellner, Ó Cofaigh, Ó Cofaigh, Ó Cofaigh, Ó Cofaigh   +71 more
core   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

Aging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu, Latif Adams, Eunice Ampem‐Danso, Justice Kumi, Abigail Aning, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Ayuba Nii Darku Ankrah, Seth Kwabena Amponsah   +8 more
wiley   +1 more source

Karakteristika të përgjithshme fiziko – gjeografike në malësinë e Çermenikës [PDF]

Micro, Macro & Mezzo Geoinformation, 2014
The highland of Çermenika is laid on the central part of the central part of Albanian Republic mountain. In that article has been treated the morphological and morphogenetical features of the Çermenika highlands, geographical position, the ...
Elvira BOLLOBANI
doaj  

Correlation Between Anatomic Landmarks and Bony Trough Position in Lateral Meniscal Allograft Transplant

Orthopaedic Journal of Sports Medicine, 2022
Background: Determining the rotational axis of the bony trough during lateral meniscal allograft transplant (MAT) is difficult. The use of anatomic landmarks may help a surgeon determine the rotational alignment of the graft during the procedure. Purpose:
Nam-Hong Choi MD, Bong-Seok Yang MD, Dong-Min Lee MD, Jong-Seok Lee MD, Brian N. Victoroff MD   +4 more
doaj   +1 more source

The unusual UV continuum of quasar Ton 34 and the possibility of crystalline dust absorption

, 2007
Luminous quasars are known to display a sharp steepening of the continuum near 1100A. This spectral feature is not well fitted by current accretion disk models, unless comptonization of the disk emission is invoked.
Binette, Luc, Krongold, Yair
core   +1 more source

Longitudinal Assessment of Biomarkers in ALS: Discriminative Biomarkers for Disease Progression and Survival

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To assess the association and discriminative performance of serum biomarkers with clinical disease progression and survival in patients with amyotrophic lateral sclerosis (ALS). Methods This retrospective study, conducted at Houston Methodist Hospital, Houston, TX, used longitudinal serum samples collected between January 2018 and ...
David R. Beers, Yueh‐Yun Lin, Jason R. Thonhoff, Aaron D. Thome, Alireza Faridar, Weihua Zhao, Shixiang Wen, Stanley H. Appel   +7 more
wiley   +1 more source

Patient-reported non-adherence and immunosuppressant trough levels are associated with rejection after renal transplantation

BMC Nephrology, 2017
Background Different measures of non-adherence to immunosuppressant (IS) medication have been found to be associated with rejection episodes after successful transplantation.
Jennifer Scheel, Sandra Reber, Lisa Stoessel, Elisabeth Waldmann, Sabine Jank, Kai-Uwe Eckardt, Franziska Grundmann, Frank Vitinius, Martina de Zwaan, Anna Bertram, Yesim Erim   +10 more
doaj   +1 more source

C/MIC > 4: A Potential Instrument to Predict the Efficacy of Meropenem

Antibiotics, 2022
This prospective study aimed to explore the determinants of meropenem trough concentration (Ctrough) in patients with bacterial pneumonia and to investigate the association between its concentration and efficacy.
Yichang Zhao, Chenlin Xiao, Jingjing Hou, Jiamin Wu, Yiwen Xiao, Bikui Zhang, Indy Sandaradura, Hong Luo, Jinhua Li, Miao Yan   +9 more
doaj   +1 more source