Results 31 to 40 of about 5,930 (185)

TRPA-driven activity-dependent structural plasticity at the Drosophila NMJ.

open access: yes, 2021
A: Schematic diagram of the NMJ submitted to a temperature stimulus that allows the entry of cations through the TRPA channels. B, D, E, G, and H: Quantification of the average number of ghost boutons at the muscle 6/7 NMJ (segment A3) with and without ...
Mariam Vazquez (11772769)   +2 more
core   +1 more source

TRPA channels distinguish gravity sensing from hearing in Johnston's organ [PDF]

open access: yesProceedings of the National Academy of Sciences, 2009
Although many animal species sense gravity for spatial orientation, the molecular bases remain uncertain. Therefore, we studied Drosophila melanogaster , which possess an inherent upward movement against gravity-negative geotaxis.
Yishan, Sun   +5 more
openaire   +2 more sources

trips4health: Protocol of a single-blinded randomised controlled trial incentivising adults to use public transport for physical activity gain

open access: yesContemporary Clinical Trials Communications, 2020
Background: Public transport (PT) users typically accumulate more physical activity (PA) than private motor vehicle users yet redressing physical inactivity through transport-related PA (TRPA) interventions has received limited attention.
M.J. Sharman   +12 more
doaj   +1 more source

The Drosophila TRPA channel, Painless, regulates sexual receptivity in virgin females [PDF]

open access: yesGenes, Brain and Behavior, 2009
Transient receptor potential (TRP) channels play crucial roles in sensory perception. Expression of the Drosophila painless (pain) gene, a homolog of the mammalian TRPA1/ANKTM1 gene, in the peripheral nervous system is required for avoidance behavior of noxious heat or wasabi.
T, Sakai   +3 more
openaire   +2 more sources

A molecular characterization of spontaneous frameshift mutagenesis within the trpA gene of Escherichia coli [PDF]

open access: yesDNA Repair, 2007
Spontaneous frameshift mutations are an important source of genetic variation in all species and cause a large number of genetic disorders in humans. To enhance our understanding of the molecular mechanisms of frameshift mutagenesis, 583 spontaneous Trp+ revertants of two trpA frameshift alleles in Escherichia coli were isolated and DNA sequenced.
Aaron, Hardin   +6 more
openaire   +2 more sources

Garlic Activate TRPA Receptor as a potential therapeutic target in skin related diseases

open access: yesPakistan BioMedical Journal, 2022
Garlic's pungent flavor has made it a prominent component in cuisines throughout the globe for decades. When chopped and put on the tongue or lips, raw garlic triggers unpleasant burning and prickling sensations by unknown processes. In this study, we demonstrate that raw garlic activates TRPA1 and TRPV1, two temperature-activated ion channels that ...
Muhammad Aqib Saeed   +7 more
openaire   +2 more sources

Temperature and TRPA-driven activity-dependent electrophysiological plasticity at the Drosophila NMJ.

open access: yes, 2021
A: Quantification of the average mEPSP frequency with and without stimulation. B: Quantification of the average mEPSP amplitude with and without stimulation. C: Quantification of the average muscle input resistance with and without stimulation.
Mariam Vazquez (11772769)   +2 more
core   +1 more source

Social ecological factors associated with physical activity and screen time amongst mothers from disadvantaged neighbourhoods over three years

open access: yesInternational Journal of Behavioral Nutrition and Physical Activity, 2020
Background Mothers from socioeconomically disadvantaged neighbourhoods are at elevated risk of physical inactivity and high levels of screen time. Yet, little is known regarding the social ecological factors that are longitudinally associated with ...
Kylie A. Morris   +3 more
doaj   +1 more source

Effect of Temperature on Heart Rate for Lucilia sericata (syn Phaenicia sericata) and Drosophila melanogaster with Altered Expression of the TrpA1 Receptors

open access: yesInsects, 2021
The transient receptor potential (TrpA—ankyrin) receptor has been linked to pathological conditions in cardiac function in mammals. To better understand the function of the TrpA1 in regulation of the heart, a Drosophila melanogaster model was used to ...
Nicole T. Marguerite   +4 more
doaj   +1 more source

Emerging role of transient receptor potential (TRP) ion channels in cardiac fibroblast pathophysiology

open access: yesFrontiers in Physiology, 2022
Cardiac fibroblasts make up a major proportion of non-excitable cells in the heart and contribute to the cardiac structural integrity and maintenance of the extracellular matrix.
Asfree Gwanyanya   +2 more
doaj   +1 more source

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